microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6789 Gene

Subcategory (RNA class) for MIR6789 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6789 Gene

  • MicroRNA 6789 2 3 5
  • Hsa-Mir-6789 2 3
  • MIR6789 2 5
  • MicroRNA Mir-6789 3
  • MIMAT0027479 50
  • MIMAT0027478 50
  • MI0022634 50

External Ids for MIR6789 Gene

Previous GeneCards Identifiers for MIR6789 Gene

  • GC19U901827

Summaries for MIR6789 Gene

Entrez Gene Summary for MIR6789 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6789 Gene

MIR6789 (MicroRNA 6789) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6789 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6789 Gene

Genomics for MIR6789 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6789 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J002234 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 0.7 -3.5 -3488 10.8 ZNF221 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 TFE3 SOX13 IKZF1 SF3A2 PLEKHJ1 ZNF77 DAZAP1 AMH LOC100288123 TCF3 DOT1L GNA11 ENSG00000267317
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6789 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6789 Gene

Genomic Locations for MIR6789 Gene
chr19:2,235,829-2,235,926
(GRCh38/hg38)
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR6789 Gene

Genes around MIR6789 on UCSC Golden Path with GeneCards custom track
MIR6789 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6789 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6789 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6789 Gene

Proteins for MIR6789 Gene

Post-translational modifications for MIR6789 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6789 Gene

Domains & Families for MIR6789 Gene

Gene Families for MIR6789 Gene

HGNC:
genes like me logo Genes that share domains with MIR6789: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6789 Gene

Function for MIR6789 Gene

Phenotypes From GWAS Catalog for MIR6789 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6789 Gene

Localization for MIR6789 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6789 Gene

Pathways & Interactions for MIR6789 Gene

PathCards logo

SuperPathways for MIR6789 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6789 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6789 Gene

Drugs & Compounds for MIR6789 Gene

No Compound Related Data Available

Transcripts for MIR6789 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6789 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AB7F_9606 precursor_RNA 98 4

HGNC: 50094,

RefSeq: NR_106847,

Ensembl: ENST00000619892 (view in UCSC) ,

miRBase: MI0022634,

URS000075DD04_9606 miRNA 24 2

RefSeq: NR_106847,

miRBase: MIMAT0027478,

URS000075E505_9606 miRNA 21 2

RefSeq: NR_106847,

miRBase: MIMAT0027479,

MIR6789 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6789 Gene

No ASD Table

Relevant External Links for MIR6789 Gene

GeneLoc Exon Structure for
MIR6789

No data available for mRNA/cDNA for MIR6789 Gene

Expression for MIR6789 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6789 Gene

Orthologs for MIR6789 Gene

Evolution for MIR6789 Gene

ENSEMBL:
Gene Tree for MIR6789 (if available)
TreeFam:
Gene Tree for MIR6789 (if available)

No data available for Orthologs for MIR6789 Gene

Paralogs for MIR6789 Gene

No data available for Paralogs for MIR6789 Gene

Variants for MIR6789 Gene

Additional dbSNP identifiers (rs#s) for MIR6789 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6789 Gene

Variant ID Type Subtype PubMed ID
dgv6218n54 CNV loss 21841781
nsv2389 CNV insertion 18451855
nsv578382 CNV loss 21841781
nsv578383 CNV loss 21841781
nsv833706 CNV loss 17160897
nsv833707 CNV loss 17160897
nsv953943 CNV deletion 24416366

Additional Variant Information for MIR6789 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6789

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6789 Gene

Disorders for MIR6789 Gene

Additional Disease Information for MIR6789

No disorders were found for MIR6789 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6789 Gene

Publications for MIR6789 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6789 Gene

Sources for MIR6789 Gene