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Aliases for MIR6789 Gene

Subcategory (RNA class) for MIR6789 Gene

miRNA

Quality Score for this RNA gene is

18

Aliases for MIR6789 Gene

  • MicroRNA 6789 2 3 5
  • MicroRNA Mir-6789 3
  • Hsa-Mir-6789 3

External Ids for MIR6789 Gene

Previous GeneCards Identifiers for MIR6789 Gene

  • GC19U901827

Summaries for MIR6789 Gene

Entrez Gene Summary for MIR6789 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6789 Gene

MIR6789 (MicroRNA 6789) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6789 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6789 Gene

Genomics for MIR6789 Gene

GeneHancer (GH) Regulatory Elements for MIR6789 Gene

Promoters and enhancers for MIR6789 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J002234 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.7 -3.6 -3589 10.6 ZNF652 ELF3 ZFX CTCF MNT NKRF POLR2A MLLT1 ZNF121 CEBPG SF3A2 PLEKHJ1 DAZAP1 ZNF77 AMH GNA11 LOC100288123 TCF3 DOT1L TLE2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6789 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6789 Gene

Genomic Locations for MIR6789 Gene
chr19:2,235,829-2,235,926
(GRCh38/hg38)
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR6789 Gene

Genes around MIR6789 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6789 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6789 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6789 Gene

ORGUL Member Location for MIR6789 Gene

ORGUL Member Location for MIR6789 gene

Proteins for MIR6789 Gene

Post-translational modifications for MIR6789 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6789 Gene

Domains & Families for MIR6789 Gene

Gene Families for MIR6789 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6789: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6789 Gene

Function for MIR6789 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6789 Gene

Localization for MIR6789 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6789 Gene

Pathways & Interactions for MIR6789 Gene

PathCards logo

SuperPathways for MIR6789 Gene

No Data Available

Interacting Proteins for MIR6789 Gene

Gene Ontology (GO) - Biological Process for MIR6789 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6789 Gene

Drugs & Compounds for MIR6789 Gene

No Compound Related Data Available

Transcripts for MIR6789 Gene

mRNA/cDNA for MIR6789 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6789 Gene

No ASD Table

Relevant External Links for MIR6789 Gene

GeneLoc Exon Structure for
MIR6789
ECgene alternative splicing isoforms for
MIR6789

Expression for MIR6789 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6789 Gene:

MIR6789
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6789 Gene

Orthologs for MIR6789 Gene

Evolution for MIR6789 Gene

ENSEMBL:
Gene Tree for MIR6789 (if available)
TreeFam:
Gene Tree for MIR6789 (if available)

No data available for Orthologs for MIR6789 Gene

Paralogs for MIR6789 Gene

No data available for Paralogs for MIR6789 Gene

Variants for MIR6789 Gene

Sequence variations from dbSNP and Humsavar for MIR6789 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000720009 -- 2,237,005(-) G/C upstream_transcript_variant
rs1000979992 -- 2,237,137(-) G/A upstream_transcript_variant
rs1001289804 -- 2,236,120(-) C/G upstream_transcript_variant
rs1002287157 -- 2,237,002(-) C/G upstream_transcript_variant
rs1002359408 -- 2,236,739(-) C/G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6789 Gene

Variant ID Type Subtype PubMed ID
dgv6218n54 CNV loss 21841781
nsv2389 CNV insertion 18451855
nsv578382 CNV loss 21841781
nsv578383 CNV loss 21841781
nsv833706 CNV loss 17160897
nsv833707 CNV loss 17160897
nsv953943 CNV deletion 24416366

Additional Variant Information for MIR6789 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6789

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6789 Gene

Disorders for MIR6789 Gene

Additional Disease Information for MIR6789

No disorders were found for MIR6789 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6789 Gene

Publications for MIR6789 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6789 Gene

Sources for MIR6789 Gene

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