microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6785 Gene

Subcategory (RNA class) for MIR6785 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6785 Gene

  • MicroRNA 6785 2 3 5
  • Hsa-Mir-6785 2 3
  • MIR6785 2 5
  • MicroRNA Mir-6785 3
  • MIMAT0027471 50
  • MIMAT0027470 50
  • MI0022630 50

External Ids for MIR6785 Gene

Previous GeneCards Identifiers for MIR6785 Gene

  • GC17U901995

Summaries for MIR6785 Gene

Entrez Gene Summary for MIR6785 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6785 Gene

MIR6785 (MicroRNA 6785) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6785 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6785 Gene

Genomics for MIR6785 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6785 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J075497 Enhancer 0.8 ENCODE dbSUPER 600.7 +0.7 696 3.1 ZBTB33 ZIC2 PATZ1 REST POLR2A ZNF600 ZNF341 SCRT2 CTCF CTBP1 MIR6785 TMEM94 LLGL2 NUP85 NT5C lnc-GRB2-1 CASKIN2
GH17J075455 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.3 -40.3 -40305 6.4 CEBPG SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 TFE3 SIX5 LEF1 TMEM94 lnc-TSEN54-2 UNK NUP85 CDK3 NT5C GGA3 ENSG00000266980 NAT9 RECQL5
GH17J075486 Promoter/Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -11.0 -11013 2.1 IKZF1 MTA1 REST ZNF24 HDAC1 SOX6 EED CBX3 UBTF SMARCA5 TMEM94 LLGL2 TSEN54 CASKIN2 NUP85 MIR6785 lnc-TSEN54-2
GH17J075474 Promoter/Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -22.4 -22399 3.3 ZIC2 SP1 ZNF341 SOX13 RFX1 RAD21 SMAD4 TFAP4 GLIS1 NR2F6 TMEM94 LLGL2 MYO15B NUP85 lnc-TSEN54-2 MIR6785 CASKIN2
GH17J075501 Enhancer 0.5 Ensembl dbSUPER 0.7 +2.9 2852 0.8 POLR2A ZBTB48 TMEM94 NUP85 MIR6785 lnc-GRB2-1 CASKIN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6785 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6785 Gene

Genomic Locations for MIR6785 Gene
chr17:75,498,548-75,498,628
(GRCh38/hg38)
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR6785 Gene

Genes around MIR6785 on UCSC Golden Path with GeneCards custom track
MIR6785 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6785 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6785 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6785 Gene

Proteins for MIR6785 Gene

Post-translational modifications for MIR6785 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6785 Gene

Domains & Families for MIR6785 Gene

Gene Families for MIR6785 Gene

HGNC:
genes like me logo Genes that share domains with MIR6785: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6785 Gene

Function for MIR6785 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6785 Gene

Localization for MIR6785 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6785 Gene

Pathways & Interactions for MIR6785 Gene

PathCards logo

SuperPathways for MIR6785 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6785 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6785 Gene

Drugs & Compounds for MIR6785 Gene

No Compound Related Data Available

Transcripts for MIR6785 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6785 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D162_9606 precursor_RNA 81 4

HGNC: 50206,

RefSeq: NR_106843,

Ensembl: ENST00000618984 (view in UCSC) ,

miRBase: MI0022630,

URS0000759E52_9606 miRNA 22 2

RefSeq: NR_106843,

miRBase: MIMAT0027470,

URS000075A0B8_9606 miRNA 21 2

RefSeq: NR_106843,

miRBase: MIMAT0027471,

MIR6785 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6785 Gene

No ASD Table

Relevant External Links for MIR6785 Gene

GeneLoc Exon Structure for
MIR6785

No data available for mRNA/cDNA for MIR6785 Gene

Expression for MIR6785 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6785 Gene

Orthologs for MIR6785 Gene

Evolution for MIR6785 Gene

ENSEMBL:
Gene Tree for MIR6785 (if available)
TreeFam:
Gene Tree for MIR6785 (if available)

No data available for Orthologs for MIR6785 Gene

Paralogs for MIR6785 Gene

No data available for Paralogs for MIR6785 Gene

Variants for MIR6785 Gene

Additional dbSNP identifiers (rs#s) for MIR6785 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6785 Gene

Variant ID Type Subtype PubMed ID
nsv470603 CNV loss 18288195
nsv516133 CNV loss 19592680
nsv576027 CNV gain 21841781
nsv833542 CNV loss 17160897
nsv952368 CNV deletion 24416366

Additional Variant Information for MIR6785 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6785

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6785 Gene

Disorders for MIR6785 Gene

Additional Disease Information for MIR6785

No disorders were found for MIR6785 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6785 Gene

Publications for MIR6785 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6785 Gene

Sources for MIR6785 Gene