Free for academic non-profit institutions. Other users need a Commercial license
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
MIR6779 (MicroRNA 6779) is an RNA Gene, and is affiliated with the miRNA class.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH17J038913 | Enhancer | 1 | ENCODE dbSUPER | 600.7 | +0.0 | 9 | 2.3 | HNRNPL GATAD2A CTCF ZBTB33 TFE3 NFKBIZ RCOR2 RXRB IRF2 SP1 | MIR6779 lnc-LINC00672-1 ENSG00000266588 LINC00672 STARD3 ENSG00000265784 LASP1 FBXO47 | |
GH17J038910 | Enhancer | 0.9 | Ensembl ENCODE dbSUPER | 0.7 | -2.7 | -2664 | 2.2 | SP1 ZBTB33 NR2F2 RCOR1 RAD21 HNF4A RXRA MAX CHD2 HNF4G | PLXDC1 LINC00672 MIR6779 ENSG00000263466 LASP1 FBXO47 | |
GH17J038908 | Enhancer | 0.6 | ENCODE dbSUPER | 0.4 | -6.2 | -6156 | 0.2 | ZIC2 RELA TCF12 MAX | ENSG00000263466 MIR6779 LASP1 FBXO47 | |
GH17J038906 | Enhancer | 0.4 | ENCODE dbSUPER | 0.4 | -8.0 | -7994 | 0.3 | SPI1 | ENSG00000263466 MIR6779 LASP1 FBXO47 | |
GH17J038907 | Enhancer | 0.2 | dbSUPER | 0.4 | -6.8 | -6827 | 0.5 | ENSG00000263466 MIR6779 LASP1 FBXO47 |
RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
---|---|---|---|---|
URS000075D7CB_9606 | precursor_RNA | 64 | 4 |
HGNC: 50148, RefSeq: NR_106837, Ensembl: ENST00000617283 (view in UCSC) , miRBase: MI0022624, |
URS000075A236_9606 | miRNA | 21 | 2 |
RefSeq: NR_106837, miRBase: MIMAT0027458, |
URS000075B933_9606 | miRNA | 21 | 2 |
RefSeq: NR_106837, miRBase: MIMAT0027459, |
No disorders were found for MIR6779 Gene.