microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6777 Gene

Subcategory (RNA class) for MIR6777 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6777 Gene

  • MicroRNA 6777 2 3 5
  • MicroRNA Mir-6777 3
  • Hsa-Mir-6777 3
  • MIMAT0027455 53
  • MIMAT0027454 53
  • MI0022622 53
  • MIR6777 2

External Ids for MIR6777 Gene

Previous GeneCards Identifiers for MIR6777 Gene

  • GC17U902045

Summaries for MIR6777 Gene

Entrez Gene Summary for MIR6777 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6777 Gene

MIR6777 (MicroRNA 6777) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6777 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6777 Gene

Genomics for MIR6777 Gene

GeneHancer (GH) Regulatory Elements for MIR6777 Gene

Promoters and enhancers for MIR6777 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J017814 Enhancer 0.3 dbSUPER 750.6 -1.1 -1141 0.9 ZFX ZBTB17 MIR33B MIR6777 lnc-TOM1L2-4 SREBF1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6777 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6777 Gene

Genomic Locations for MIR6777 Gene
chr17:17,813,480-17,813,545
(GRCh38/hg38)
Size:
66 bases
Orientation:
Minus strand

Genomic View for MIR6777 Gene

Genes around MIR6777 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6777 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6777 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6777 Gene

Proteins for MIR6777 Gene

Post-translational modifications for MIR6777 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6777 Gene

Domains & Families for MIR6777 Gene

Gene Families for MIR6777 Gene

HGNC:
genes like me logo Genes that share domains with MIR6777: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6777 Gene

Function for MIR6777 Gene

Phenotypes From GWAS Catalog for MIR6777 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6777 Gene

Localization for MIR6777 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6777 Gene

Pathways & Interactions for MIR6777 Gene

PathCards logo

SuperPathways for MIR6777 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6777 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6777 Gene

Drugs & Compounds for MIR6777 Gene

No Compound Related Data Available

Transcripts for MIR6777 Gene

mRNA/cDNA for MIR6777 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6777 Gene

No ASD Table

Relevant External Links for MIR6777 Gene

GeneLoc Exon Structure for
MIR6777
ECgene alternative splicing isoforms for
MIR6777

Expression for MIR6777 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6777 Gene:

MIR6777
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6777 Gene

Orthologs for MIR6777 Gene

Evolution for MIR6777 Gene

ENSEMBL:
Gene Tree for MIR6777 (if available)
TreeFam:
Gene Tree for MIR6777 (if available)

No data available for Orthologs for MIR6777 Gene

Paralogs for MIR6777 Gene

No data available for Paralogs for MIR6777 Gene

Variants for MIR6777 Gene

Sequence variations from dbSNP and Humsavar for MIR6777 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000978803 -- 17,814,565(-) G/A upstream_transcript_variant
rs1001475002 -- 17,813,803(-) G/A upstream_transcript_variant
rs1002484609 -- 17,815,139(-) C/G upstream_transcript_variant
rs1004143021 -- 17,814,164(-) CCCC/CCCCC upstream_transcript_variant
rs1004549247 -- 17,814,056(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6777 Gene

Variant ID Type Subtype PubMed ID
nsv155 OTHER inversion 15895083
nsv499114 OTHER inversion 21111241
nsv522668 CNV loss 19592680
nsv833385 CNV loss 17160897
nsv953838 CNV deletion 24416366

Additional Variant Information for MIR6777 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6777

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6777 Gene

Disorders for MIR6777 Gene

Additional Disease Information for MIR6777

No disorders were found for MIR6777 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6777 Gene

Publications for MIR6777 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6777 Gene

Sources for MIR6777 Gene