microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6770-2 Gene

Subcategory (RNA class) for MIR6770-2 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6770-2 Gene

  • MicroRNA 6770-2 2 3 5
  • Hsa-Mir-6770-2 2 3
  • MIR6770-2 2 5
  • MicroRNA Mir-6770-2 3
  • MIMAT0027441 50
  • MIMAT0027440 50
  • MI0026418 50
  • MIR6770-3 2
  • MI0022615 50
  • MI0026419 50
  • MIR6770-1 2

External Ids for MIR6770-2 Gene

Previous GeneCards Identifiers for MIR6770-2 Gene

  • GC16U901742

Summaries for MIR6770-2 Gene

Entrez Gene Summary for MIR6770-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6770-2 Gene

MIR6770-2 (MicroRNA 6770-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6770-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6770-2 Gene

Genomics for MIR6770-2 Gene

Genomic Locations for MIR6770-2 Gene

Genomic Locations for MIR6770-2 Gene
chr16:16,329,305-16,329,364
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand

Genomic View for MIR6770-2 Gene

Genes around MIR6770-2 on UCSC Golden Path with GeneCards custom track
MIR6770-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6770-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6770-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6770-2 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR6770-2 Gene

Proteins for MIR6770-2 Gene

Post-translational modifications for MIR6770-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6770-2 Gene

Domains & Families for MIR6770-2 Gene

Gene Families for MIR6770-2 Gene

HGNC:
genes like me logo Genes that share domains with MIR6770-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6770-2 Gene

Function for MIR6770-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6770-2 Gene

Localization for MIR6770-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6770-2 Gene

Pathways & Interactions for MIR6770-2 Gene

PathCards logo

SuperPathways for MIR6770-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6770-2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6770-2 Gene

Drugs & Compounds for MIR6770-2 Gene

No Compound Related Data Available

Transcripts for MIR6770-2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6770-2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B619_9606 precursor_RNA 60 4

HGNC: 50034, 50115, 50223,

RefSeq: NR_106828, NR_107060, NR_107061,

Ensembl: ENST00000616362 (view in UCSC) , ENST00000618304 (view in UCSC) , ENST00000622248 (view in UCSC) ,

miRBase: MI0022615, MI0026418, MI0026419,

URS000075A6A9_9606 miRNA 24 2

RefSeq: NR_106828, NR_107060, NR_107061,

miRBase: MIMAT0027440,

URS000075D6C4_9606 miRNA 21 2

RefSeq: NR_106828, NR_107060, NR_107061,

miRBase: MIMAT0027441,

MIR6770-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6770-2 Gene

No ASD Table

Relevant External Links for MIR6770-2 Gene

GeneLoc Exon Structure for
MIR6770-2

No data available for mRNA/cDNA for MIR6770-2 Gene

Expression for MIR6770-2 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6770-2 Gene

Orthologs for MIR6770-2 Gene

Evolution for MIR6770-2 Gene

ENSEMBL:
Gene Tree for MIR6770-2 (if available)
TreeFam:
Gene Tree for MIR6770-2 (if available)

No data available for Orthologs for MIR6770-2 Gene

Paralogs for MIR6770-2 Gene

No data available for Paralogs for MIR6770-2 Gene

Variants for MIR6770-2 Gene

Additional dbSNP identifiers (rs#s) for MIR6770-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6770-2 Gene

Variant ID Type Subtype PubMed ID
dgv111n111 CNV duplication 26073780
dgv112n111 CNV duplication 26073780
dgv2738n100 CNV gain 25217958
dgv2740n100 CNV loss 25217958
dgv2741n100 CNV gain+loss 25217958
dgv2742n100 CNV gain 25217958
dgv2744n100 CNV loss 25217958
dgv2745n100 CNV gain 25217958
dgv2746n100 CNV gain+loss 25217958
dgv2747n100 CNV loss 25217958
dgv2749n100 CNV gain 25217958
dgv2750n100 CNV loss 25217958
dgv2751n100 CNV gain 25217958
dgv2752n100 CNV gain+loss 25217958
dgv2753n100 CNV loss 25217958
dgv2754n100 CNV loss 25217958
dgv2755n100 CNV gain 25217958
dgv2756n100 CNV loss 25217958
dgv2757n100 CNV gain+loss 25217958
dgv2775n100 CNV gain 25217958
dgv2776n100 CNV gain+loss 25217958
dgv2777n100 CNV loss 25217958
dgv2781n100 CNV gain+loss 25217958
dgv2782n100 CNV loss 25217958
dgv2783n100 CNV gain 25217958
dgv2784n100 CNV gain 25217958
dgv2n1 OTHER inversion 15895083
dgv4924n54 CNV gain 21841781
dgv791e212 CNV loss 25503493
esv22206 CNV gain+loss 19812545
esv2631582 CNV gain 19546169
esv2714015 CNV deletion 23290073
esv2751550 CNV gain 17911159
esv2758632 CNV gain+loss 17122850
esv2758633 CNV gain+loss 17122850
esv2758634 CNV gain+loss 17122850
esv2760416 CNV gain+loss 21179565
esv2762254 CNV gain+loss 21179565
esv2762276 CNV gain+loss 21179565
esv28069 CNV gain+loss 19812545
esv28183 CNV gain+loss 19812545
esv32598 CNV gain 17666407
esv33614 CNV gain+loss 17666407
esv34419 CNV gain 17911159
esv3570331 CNV gain 25503493
esv3570398 CNV gain 25503493
esv3582069 CNV loss 25503493
esv3584701 CNV loss 24956385
nsv1038955 CNV loss 25217958
nsv1043239 CNV gain 25217958
nsv1047898 CNV loss 25217958
nsv1048002 CNV gain 25217958
nsv1049647 CNV gain+loss 25217958
nsv1124728 CNV duplication 24896259
nsv1125134 CNV deletion 24896259
nsv1141278 CNV duplication 24896259
nsv1146292 CNV duplication 26484159
nsv1149967 CNV duplication 26484159
nsv1151531 CNV duplication 26484159
nsv1160344 CNV deletion 26073780
nsv1160345 CNV duplication 26073780
nsv1160346 CNV duplication 26073780
nsv1160365 CNV duplication 26073780
nsv136 OTHER inversion 15895083
nsv1751 CNV deletion 18451855
nsv428319 CNV loss 18775914
nsv428320 CNV loss 18775914
nsv433435 CNV gain 18776910
nsv435664 CNV deletion 17901297
nsv442710 CNV gain 18776908
nsv457428 CNV gain 19166990
nsv499081 OTHER inversion 21111241
nsv499138 OTHER inversion 21111241
nsv509599 CNV insertion 20534489
nsv509601 CNV insertion 20534489
nsv511045 OTHER complex 20534489
nsv7277 OTHER inversion 18451855
nsv7278 OTHER inversion 18451855
nsv819280 CNV loss 19587683
nsv820784 CNV deletion 20802225
nsv820818 CNV deletion 20802225
nsv833160 CNV gain 17160897
nsv9377 CNV gain 18304495
nsv952930 CNV deletion 24416366
nsv952938 CNV deletion 24416366
nsv952943 CNV deletion 24416366
nsv974762 CNV duplication 23825009
nsv977919 CNV duplication 23825009
nsv977930 CNV duplication 23825009

Additional Variant Information for MIR6770-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6770-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6770-2 Gene

Disorders for MIR6770-2 Gene

Additional Disease Information for MIR6770-2

No disorders were found for MIR6770-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6770-2 Gene

Publications for MIR6770-2 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6770-2 Gene

Sources for MIR6770-2 Gene