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Aliases for MIR6769A Gene

Subcategory (RNA class) for MIR6769A Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6769A Gene

  • MicroRNA 6769a 2 3 5
  • MicroRNA Mir-6769a 3
  • Hsa-Mir-6769a 3

External Ids for MIR6769A Gene

Previous GeneCards Identifiers for MIR6769A Gene

  • GC16U901790

Summaries for MIR6769A Gene

Entrez Gene Summary for MIR6769A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6769A Gene

MIR6769A (MicroRNA 6769a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6769A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6769A Gene

Genomics for MIR6769A Gene

GeneHancer (GH) Regulatory Elements for MIR6769A Gene

Promoters and enhancers for MIR6769A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J004672 Enhancer 0.5 ENCODE dbSUPER 600.7 +1.4 1448 0.9 ZNF121 MIR6769A MGRN1 NUDT16L1
GH16J004658 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.8 -8765 7.3 ELF3 MNT POLR2A CEBPG RERE AHR MAFK TFE3 SP1 SP5 MGRN1 NUDT16L1 PPL SEPTIN12 CORO7 GLYR1 NAGPA ENSG00000278700 MIR6769A
GH16J004668 Enhancer 1 Ensembl dbSUPER 0.7 -2.7 -2717 0.4 MTA3 ZNF24 ZNF488 YBX1 ZNF776 MTA2 ZNF239 ZNF148 ZNF311 ZNF747 ZNF500 CREBBP MGRN1 ANKS3 ALG1 UBN1 EEF2KMT GLYR1 SEC14L5 MIR6769A
GH16J004675 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 0.4 +6.9 6907 6.3 ZNF121 NFIB SP1 POLR2A RXRA DPF2 ZIC2 TARDBP YY1 ZBTB33 MGRN1 ZNF500 MIR6769A NUDT16L1
GH16J004681 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +11.3 11343 1.8 ZNF148 SP1 ZBTB33 ZIC2 CTCF ZBTB26 GABPB1 RAD21 NFIL3 ZNF143 MGRN1 ZNF500 CORO7 ROGDI NUDT16L1 MIR6769A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6769A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6769A Gene

Genomic Locations for MIR6769A Gene
chr16:4,671,318-4,671,390
(GRCh38/hg38)
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR6769A Gene

Genes around MIR6769A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6769A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6769A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6769A Gene

Proteins for MIR6769A Gene

Post-translational modifications for MIR6769A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6769A Gene

Domains & Families for MIR6769A Gene

Gene Families for MIR6769A Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6769A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6769A Gene

Function for MIR6769A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6769A Gene

Localization for MIR6769A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6769A Gene

Pathways & Interactions for MIR6769A Gene

PathCards logo

SuperPathways for MIR6769A Gene

No Data Available

Interacting Proteins for MIR6769A Gene

Gene Ontology (GO) - Biological Process for MIR6769A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6769A Gene

Drugs & Compounds for MIR6769A Gene

No Compound Related Data Available

Transcripts for MIR6769A Gene

mRNA/cDNA for MIR6769A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6769A Gene

No ASD Table

Relevant External Links for MIR6769A Gene

GeneLoc Exon Structure for
MIR6769A
ECgene alternative splicing isoforms for
MIR6769A

Expression for MIR6769A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6769A Gene:

MIR6769A
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6769A Gene

Orthologs for MIR6769A Gene

Evolution for MIR6769A Gene

ENSEMBL:
Gene Tree for MIR6769A (if available)
TreeFam:
Gene Tree for MIR6769A (if available)

No data available for Orthologs for MIR6769A Gene

Paralogs for MIR6769A Gene

No data available for Paralogs for MIR6769A Gene

Variants for MIR6769A Gene

Sequence variations from dbSNP and Humsavar for MIR6769A Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000880409 -- 4,669,633(+) A/C upstream_transcript_variant
rs1001700854 -- 4,670,312(+) A/G upstream_transcript_variant
rs1001998592 -- 4,669,326(+) C/G upstream_transcript_variant
rs1003496489 -- 4,670,374(+) C/T upstream_transcript_variant
rs1004397051 -- 4,669,349(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6769A Gene

Variant ID Type Subtype PubMed ID
esv3637699 CNV loss 21293372
nsv1046986 CNV gain 25217958
nsv1050237 CNV loss 25217958
nsv1160333 CNV deletion 26073780

Additional Variant Information for MIR6769A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6769A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6769A Gene

Disorders for MIR6769A Gene

Additional Disease Information for MIR6769A

No disorders were found for MIR6769A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6769A Gene

Publications for MIR6769A Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6769A Gene

Sources for MIR6769A Gene

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