microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6768 Gene

Subcategory (RNA class) for MIR6768 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6768 Gene

  • MicroRNA 6768 2 3 5
  • MicroRNA Mir-6768 3
  • Hsa-Mir-6768 3
  • MIMAT0027437 53
  • MIMAT0027436 53
  • MI0022613 53
  • MIR6768 2

External Ids for MIR6768 Gene

Previous GeneCards Identifiers for MIR6768 Gene

  • GC16U901762

Summaries for MIR6768 Gene

Entrez Gene Summary for MIR6768 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6768 Gene

MIR6768 (MicroRNA 6768) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6768 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6768 Gene

Genomics for MIR6768 Gene

GeneHancer (GH) Regulatory Elements for MIR6768 Gene

Promoters and enhancers for MIR6768 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J002463 Enhancer 0.8 Ensembl dbSUPER 750.6 -0.4 -366 1.2 ZNF362 SP7 GLIS2 ZIC2 ZEB2 ZNF629 OSR2 GLI4 WT1 ZNF335 MIR6768 ZNF213-AS1 ENSG00000260778 ZNF75A TBC1D24 TEDC2
GH16J002460 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.6 -3.9 -3866 2.6 SIN3A SP1 ZBTB40 MLX POLR2A NFYC RBM39 L3MBTL2 MAX ZNF121 ENSG00000260874 LOC105371050 TEDC2 SRRM2 ENSG00000255513 SNORA64 ENSG00000260954 ENSG00000262482 THOC6 ZNF263
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6768 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6768 Gene

Genomic Locations for MIR6768 Gene
chr16:2,463,967-2,464,038
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR6768 Gene

Genes around MIR6768 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6768 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6768 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6768 Gene

Proteins for MIR6768 Gene

Post-translational modifications for MIR6768 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6768 Gene

Domains & Families for MIR6768 Gene

Gene Families for MIR6768 Gene

HGNC:
genes like me logo Genes that share domains with MIR6768: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6768 Gene

Function for MIR6768 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6768 Gene

Localization for MIR6768 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6768 Gene

Pathways & Interactions for MIR6768 Gene

PathCards logo

SuperPathways for MIR6768 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6768 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6768 Gene

Drugs & Compounds for MIR6768 Gene

No Compound Related Data Available

Transcripts for MIR6768 Gene

mRNA/cDNA for MIR6768 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6768 Gene

No ASD Table

Relevant External Links for MIR6768 Gene

GeneLoc Exon Structure for
MIR6768
ECgene alternative splicing isoforms for
MIR6768

Expression for MIR6768 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6768 Gene:

MIR6768
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6768 Gene

Orthologs for MIR6768 Gene

Evolution for MIR6768 Gene

ENSEMBL:
Gene Tree for MIR6768 (if available)
TreeFam:
Gene Tree for MIR6768 (if available)

No data available for Orthologs for MIR6768 Gene

Paralogs for MIR6768 Gene

No data available for Paralogs for MIR6768 Gene

Variants for MIR6768 Gene

Sequence variations from dbSNP and Humsavar for MIR6768 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1004908342 -- 2,463,042(+) C/G upstream_transcript_variant
rs1005498493 -- 2,462,739(+) C/A upstream_transcript_variant
rs1007682104 -- 2,463,044(+) G/A upstream_transcript_variant
rs1008430439 -- 2,463,727(+) C/T upstream_transcript_variant
rs1009840252 -- 2,463,415(+) T/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6768 Gene

Variant ID Type Subtype PubMed ID
dgv4864n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
nsv1052260 CNV gain 25217958
nsv833121 CNV loss 17160897
nsv952903 CNV deletion 24416366

Additional Variant Information for MIR6768 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6768

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6768 Gene

Disorders for MIR6768 Gene

Additional Disease Information for MIR6768

No disorders were found for MIR6768 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6768 Gene

Publications for MIR6768 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6768 Gene

Sources for MIR6768 Gene