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Aliases for MIR6764 Gene

Subcategory (RNA class) for MIR6764 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6764 Gene

  • MicroRNA 6764 2 3 5
  • MicroRNA Mir-6764 3
  • Hsa-Mir-6764 3

External Ids for MIR6764 Gene

Previous GeneCards Identifiers for MIR6764 Gene

  • GC14U901454
  • GC14P100240

Summaries for MIR6764 Gene

Entrez Gene Summary for MIR6764 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6764 Gene

MIR6764 (MicroRNA 6764) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6764 include Gabriele-De Vries Syndrome. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Sterol Regulatory Element-Binding Proteins (SREBP) signalling.

Additional gene information for MIR6764 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6764 Gene

Genomics for MIR6764 Gene

GeneHancer (GH) Regulatory Elements for MIR6764 Gene

Promoters and enhancers for MIR6764 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J100278 Enhancer 1.4 UCNEbase Ensembl ENCODE dbSUPER 600.7 +1.6 1644 2 CTCF PPARG SOX13 SCRT2 NFE2 RUNX3 PKNOX1 TEAD1 KDM1A NR2F6 GC14P100279 MIR6764 SLC25A29 MIR345 WARS WDR25 SLC25A47 MIR342 GC14P100276 ENSG00000259052
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6764 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6764 Gene

Genomic Locations for MIR6764 Gene
chr14:100,277,357-100,277,417
(GRCh38/hg38)
Size:
61 bases
Orientation:
Plus strand

Genomic View for MIR6764 Gene

Genes around MIR6764 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6764 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6764 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6764 Gene

Proteins for MIR6764 Gene

Post-translational modifications for MIR6764 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6764 Gene

Domains & Families for MIR6764 Gene

Gene Families for MIR6764 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6764: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6764 Gene

Function for MIR6764 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6764 Gene

Localization for MIR6764 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6764 Gene

Pathways & Interactions for MIR6764 Gene

genes like me logo Genes that share pathways with MIR6764: view

Interacting Proteins for MIR6764 Gene

Gene Ontology (GO) - Biological Process for MIR6764 Gene

None

No data available for SIGNOR curated interactions for MIR6764 Gene

Drugs & Compounds for MIR6764 Gene

No Compound Related Data Available

Transcripts for MIR6764 Gene

mRNA/cDNA for MIR6764 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6764 Gene

No ASD Table

Relevant External Links for MIR6764 Gene

GeneLoc Exon Structure for
MIR6764
ECgene alternative splicing isoforms for
MIR6764

Expression for MIR6764 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6764 Gene:

MIR6764
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6764 Gene

Orthologs for MIR6764 Gene

Evolution for MIR6764 Gene

ENSEMBL:
Gene Tree for MIR6764 (if available)
TreeFam:
Gene Tree for MIR6764 (if available)

No data available for Orthologs for MIR6764 Gene

Paralogs for MIR6764 Gene

No data available for Paralogs for MIR6764 Gene

Variants for MIR6764 Gene

Sequence variations from dbSNP and Humsavar for MIR6764 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1131692043 pathogenic, GABRIELE-DE VRIES SYNDROME 100,277,493(+) G/T downstream_transcript_variant
rs1131692044 pathogenic, GABRIELE-DE VRIES SYNDROME 100,277,451(+) C/G downstream_transcript_variant
rs1131692045 pathogenic, GABRIELE-DE VRIES SYNDROME 100,276,616(+) C/T upstream_transcript_variant
rs1131692163 pathogenic, GABRIELE-DE VRIES SYNDROME 100,277,452(+) T/C downstream_transcript_variant
rs1555370868 uncertain-significance, Inborn genetic diseases 100,276,601(+) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6764 Gene

Variant ID Type Subtype PubMed ID
esv2749108 CNV deletion 23290073
esv3635496 CNV gain 21293372
esv3635502 CNV gain 21293372
nsv832875 CNV loss 17160897

Additional Variant Information for MIR6764 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6764

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6764 Gene

Disorders for MIR6764 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6764 Gene - From: GeneCards

Disorder Aliases PubMed IDs
gabriele-de vries syndrome
  • gadevs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6764

genes like me logo Genes that share disorders with MIR6764: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6764 Gene

Publications for MIR6764 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6764 Gene

Sources for MIR6764 Gene

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