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Aliases for MIR6758 Gene

Subcategory (RNA class) for MIR6758 Gene


Quality Score for this RNA gene is


Aliases for MIR6758 Gene

  • MicroRNA 6758 2 3 5
  • MicroRNA Mir-6758 3
  • Hsa-Mir-6758 3

External Ids for MIR6758 Gene

Previous GeneCards Identifiers for MIR6758 Gene

  • GC12U901933

Summaries for MIR6758 Gene

Entrez Gene Summary for MIR6758 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6758 Gene

MIR6758 (MicroRNA 6758) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Gene Expression and tRNA Aminoacylation.

Additional gene information for MIR6758 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6758 Gene

Genomics for MIR6758 Gene

GeneHancer (GH) Regulatory Elements for MIR6758 Gene

Promoters and enhancers for MIR6758 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I057511 Enhancer 0.5 dbSUPER 550.8 -0.4 -397 2.3 ZFHX2 POLR2A SCRT2 REST ZBTB33 SUPT5H EGR2 GC12P057513 MIR6758 DCTN2 EEF1AKMT3 ARHGAP9 MARS
GH12I057498 Enhancer 0.5 ENCODE 0.4 -14.4 -14355 0.2 CTCF FOXA2 POLR2A ZBTB33 SUPT5H ARHGAP9 MIR6758 MARS
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR6758 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6758 Gene

Genomic Locations for MIR6758 Gene
63 bases
Plus strand

Genomic View for MIR6758 Gene

Genes around MIR6758 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6758 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6758 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6758 Gene

Proteins for MIR6758 Gene

Post-translational modifications for MIR6758 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6758 Gene

Domains & Families for MIR6758 Gene

Gene Families for MIR6758 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6758: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6758 Gene

Function for MIR6758 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6758 Gene

Localization for MIR6758 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6758 Gene

Pathways & Interactions for MIR6758 Gene

genes like me logo Genes that share pathways with MIR6758: view

Interacting Proteins for MIR6758 Gene

Gene Ontology (GO) - Biological Process for MIR6758 Gene


No data available for SIGNOR curated interactions for MIR6758 Gene

Drugs & Compounds for MIR6758 Gene

No Compound Related Data Available

Transcripts for MIR6758 Gene

mRNA/cDNA for MIR6758 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6758 Gene

No ASD Table

Relevant External Links for MIR6758 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR6758 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6758 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6758 Gene

Orthologs for MIR6758 Gene

Evolution for MIR6758 Gene

Gene Tree for MIR6758 (if available)
Gene Tree for MIR6758 (if available)

No data available for Orthologs for MIR6758 Gene

Paralogs for MIR6758 Gene

No data available for Paralogs for MIR6758 Gene

Variants for MIR6758 Gene

Sequence variations from dbSNP and Humsavar for MIR6758 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs117633211 benign, Charcot-Marie-Tooth disease, axonal, type 2u, Interstitial lung and liver disease 57,512,809(+) G/A downstream_transcript_variant
rs117833843 benign, not specified, Charcot-Marie-Tooth disease, axonal, type 2u, Interstitial lung and liver disease 57,512,289(+) C/A/G/T upstream_transcript_variant
rs117914586 uncertain-significance, likely-benign, benign, not provided, not specified, Charcot-Marie-Tooth disease, axonal, type 2u, Interstitial lung and liver disease 57,512,360(+) A/G upstream_transcript_variant
rs143592405 pathogenic, Pulmonary alveolar proteinosis, Interstitial lung and liver disease 57,512,300(+) C/T upstream_transcript_variant
rs201555303 pathogenic, Interstitial lung and liver disease 57,512,036(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6758 Gene

Variant ID Type Subtype PubMed ID
dgv2651n54 CNV loss 21841781
esv2759901 CNV gain 17122850
esv3419248 CNV duplication 20981092
nsv428283 CNV gain 18775914
nsv469411 CNV loss 19166990
nsv482992 CNV gain+loss 15286789
nsv559034 CNV loss 21841781

Additional Variant Information for MIR6758 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6758 Gene

Disorders for MIR6758 Gene

Additional Disease Information for MIR6758

No disorders were found for MIR6758 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6758 Gene

Publications for MIR6758 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6758 Gene

Sources for MIR6758 Gene

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