microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6756 Gene

Subcategory (RNA class) for MIR6756 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6756 Gene

  • MicroRNA 6756 2 3 5
  • MicroRNA Mir-6756 3
  • Hsa-Mir-6756 3
  • MIMAT0027412 53
  • MIMAT0027413 53
  • MI0022601 53
  • MIR6756 2

External Ids for MIR6756 Gene

Previous GeneCards Identifiers for MIR6756 Gene

  • GC11U902136

Summaries for MIR6756 Gene

Entrez Gene Summary for MIR6756 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6756 Gene

MIR6756 (MicroRNA 6756) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6756 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6756 Gene

Genomics for MIR6756 Gene

GeneHancer (GH) Regulatory Elements for MIR6756 Gene

Promoters and enhancers for MIR6756 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J119312 Enhancer 0.2 dbSUPER 750.6 +0.4 382 1.2 MIR6756 lnc-C1QTNF5-6 ENSG00000245385 RNF26 C1QTNF5 MFRP ABCG4 PDZD3 NLRX1 MCAM
GH11J119314 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -5.8 -5783 8.2 ZBTB40 CTCF SMARCE1 POLR2A ATF1 CREB1 MYC ELF1 L3MBTL2 MAX MCAM RNF26 ENSG00000245869 BCL9L CBL IFT46 RPS25 ENSG00000271751 lnc-C1QTNF5-5 lnc-C1QTNF5-8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6756 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6756 Gene

Genomic Locations for MIR6756 Gene
chr11:119,312,950-119,313,012
(GRCh38/hg38)
Size:
63 bases
Orientation:
Minus strand

Genomic View for MIR6756 Gene

Genes around MIR6756 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6756 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6756 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6756 Gene

Proteins for MIR6756 Gene

Post-translational modifications for MIR6756 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6756 Gene

Domains & Families for MIR6756 Gene

Gene Families for MIR6756 Gene

HGNC:
genes like me logo Genes that share domains with MIR6756: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6756 Gene

Function for MIR6756 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6756 Gene

Localization for MIR6756 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6756 Gene

Pathways & Interactions for MIR6756 Gene

PathCards logo

SuperPathways for MIR6756 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6756 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6756 Gene

Drugs & Compounds for MIR6756 Gene

No Compound Related Data Available

Transcripts for MIR6756 Gene

mRNA/cDNA for MIR6756 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6756 Gene

No ASD Table

Relevant External Links for MIR6756 Gene

GeneLoc Exon Structure for
MIR6756
ECgene alternative splicing isoforms for
MIR6756

Expression for MIR6756 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6756 Gene:

MIR6756
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6756 Gene

Orthologs for MIR6756 Gene

Evolution for MIR6756 Gene

ENSEMBL:
Gene Tree for MIR6756 (if available)
TreeFam:
Gene Tree for MIR6756 (if available)

No data available for Orthologs for MIR6756 Gene

Paralogs for MIR6756 Gene

No data available for Paralogs for MIR6756 Gene

Variants for MIR6756 Gene

Sequence variations from dbSNP and Humsavar for MIR6756 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000143348 -- 119,313,953(-) T/C upstream_transcript_variant
rs1001098778 -- 119,312,622(-) C/T downstream_transcript_variant
rs1001376773 -- 119,314,895(-) A/G upstream_transcript_variant
rs1002787158 -- 119,313,414(-) T/C upstream_transcript_variant
rs1008291553 -- 119,313,000(-) C/G/T non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6756 Gene

Variant ID Type Subtype PubMed ID
nsv556469 CNV gain 21841781
nsv952747 CNV deletion 24416366

Additional Variant Information for MIR6756 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6756

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6756 Gene

Disorders for MIR6756 Gene

Additional Disease Information for MIR6756

No disorders were found for MIR6756 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6756 Gene

Publications for MIR6756 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6756 Gene

Sources for MIR6756 Gene