MIR6748 Gene (RNA Gene)

MicroRNA 6748

GC11P062791
GIFtS:
11
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6748 Gene

Subcategory (RNA class) for MIR6748 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6748 Gene

  • MicroRNA 6748 2 3 5
  • MicroRNA Mir-6748 3
  • Hsa-Mir-6748 3
  • MIMAT0027397 53
  • MIMAT0027396 53
  • MI0022593 53
  • MIR6748 2

External Ids for MIR6748 Gene

Previous GeneCards Identifiers for MIR6748 Gene

  • GC11U902228

Summaries for MIR6748 Gene

Entrez Gene Summary for MIR6748 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6748 Gene

MIR6748 (MicroRNA 6748) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Innate Immune System.

Additional gene information for MIR6748 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6748 Gene

Genomics for MIR6748 Gene

GeneHancer (GH) Regulatory Elements for MIR6748 Gene

Promoters and enhancers for MIR6748 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH11J062790 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 +1.8 1835 2.9 PPP1R10 ZBTB40 RBPJ POLR2A ZNF362 MYC ELF1 L3MBTL2 MAX MNT TMEM223 MIR6514 MIR6748 lnc-TMEM223-1 piR-55414 GANAB NXF1 INTS5 TMEM179B BSCL2
GH11J062785 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.6 -2.3 -2267 3.5 SIN3A ZBTB40 SP1 CTCF FOXA1 RBPJ SMARCE1 POLR2A ATF1 CREB1 TMEM179B ENSG00000269176 NONHSAG008544.2 GANAB NXF1 INTS5 EML3 CSKMT IMMP1LP1 UBXN1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6748 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6748 Gene

Genomic Locations for MIR6748 Gene
chr11:62,789,815-62,789,885
(GRCh38/hg38)
Size:
71 bases
Orientation:
Plus strand

Genomic View for MIR6748 Gene

Genes around MIR6748 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6748 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6748 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR6748 Gene

Proteins for MIR6748 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR6748 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6748 Gene

Domains & Families for MIR6748 Gene

Gene Families for MIR6748 Gene

HGNC:
genes like me logo Genes that share domains with MIR6748: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6748 Gene

Function for MIR6748 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6748 Gene

Localization for MIR6748 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6748 Gene

Pathways & Interactions for MIR6748 Gene

PathCards logo

SuperPathways for MIR6748 Gene

genes like me logo Genes that share pathways with MIR6748: view

Pathways by source for MIR6748 Gene

3 Reactome pathways for MIR6748 Gene

Gene Ontology (GO) - Biological Process for MIR6748 Gene

None

No data available for SIGNOR curated interactions for MIR6748 Gene

Drugs & Compounds for MIR6748 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR6748 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR6748 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6748 Gene

No ASD Table

Relevant External Links for MIR6748 Gene

GeneLoc Exon Structure for
MIR6748
ECgene alternative splicing isoforms for
MIR6748

Expression for MIR6748 Gene

Products:

  1. Primer
  2. Gene Expression Assay

NURSA nuclear receptor signaling pathways regulating expression of MIR6748 Gene:

MIR6748
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6748 Gene

Orthologs for MIR6748 Gene

Evolution for MIR6748 Gene

ENSEMBL:
Gene Tree for MIR6748 (if available)
TreeFam:
Gene Tree for MIR6748 (if available)

No data available for Orthologs for MIR6748 Gene

Paralogs for MIR6748 Gene

No data available for Paralogs for MIR6748 Gene

Variants for MIR6748 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for MIR6748 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1002308087 -- 62,787,940(+) T/A upstream_transcript_variant
rs1002413832 -- 62,788,815(+) C/G upstream_transcript_variant
rs1003279399 -- 62,788,957(+) C/T upstream_transcript_variant
rs1003370211 -- 62,787,905(+) A/G upstream_transcript_variant
rs1003721706 -- 62,789,241(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6748 Gene

Variant ID Type Subtype PubMed ID
nsv508636 CNV deletion 20534489
nsv509416 CNV insertion 20534489

Additional Variant Information for MIR6748 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6748

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6748 Gene

Disorders for MIR6748 Gene

Additional Disease Information for MIR6748

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR6748 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6748 Gene

Publications for MIR6748 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

ExternalLinks

View latest publications for MIR6748 gene in Mastermind

Products for MIR6748 Gene

Sources for MIR6748 Gene