Free for academic non-profit institutions. Other users need a Commercial license
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
MIR6747 (MicroRNA 6747) is an RNA Gene, and is affiliated with the miRNA class.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11J062565 | Enhancer | 0.7 | Ensembl dbSUPER | 250.7 | +0.1 | 54 | 2 | ZNF316 ELF1 ZBTB33 IKZF1 HSF1 POLR2A IKZF2 | MIR6747 EML3 ENSG00000255508 TUT1 MTA2 ENSG00000254964 ENSG00000257058 ENSG00000250659 ENSG00000255446 ENSG00000255126 | |
GH11J062564 | Enhancer | 0.5 | Ensembl dbSUPER | 250.7 | +1.9 | 1870 | 0.4 | ZNF18 SP1 | MIR6747 ENSG00000255508 TUT1 MTA2 ENSG00000254964 EML3 ENSG00000250659 ENSG00000255446 ENSG00000255126 SCGB1A1 | |
GH11J062569 | Enhancer | 0.3 | dbSUPER | 0.7 | -3.1 | -3121 | 1.7 | SPI1 RBFOX2 | piR-61960-001 EML3 ENSG00000255508 TUT1 MTA2 ENSG00000254964 ENSG00000257058 ENSG00000250659 ENSG00000255446 ENSG00000255126 | |
GH11J062563 | Enhancer | 0.3 | dbSUPER | 0.7 | +3.1 | 3068 | 0.6 | POLR2A | ENSG00000255508 TUT1 MTA2 ENSG00000254964 EML3 ENSG00000250659 ENSG00000255446 SCGB1A1 ENSG00000255126 ASRGL1 |
RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
---|---|---|---|---|
URS000075BE67_9606 | pre_miRNA | 61 | 3 |
RefSeq: NR_106805, Ensembl: ENST00000617193 (view in UCSC) , miRBase: MI0022592, |
URS000075B922_9606 | miRNA | 21 | 3 |
RefSeq: NR_106805, LncBase: hsa-miR-6747-3p, miRBase: MIMAT0027395, |
URS000075A10C_9606 | miRNA | 24 | 2 |
RefSeq: NR_106805, miRBase: MIMAT0027394, |
No disorders were found for MIR6747 Gene.