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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR6747 Gene
Data sources for MIR6747 Gene:
Subcategory (RNA class) for MIR6747 Gene
miRNA
Aliases for MIR6747 Gene
- MicroRNA 6747 (HGNC, NCBI Entrez Gene, Ensembl)
- Hsa-Mir-6747 (HGNC, NCBI Entrez Gene)
- MicroRNA Mir-6747 (NCBI Entrez Gene)
- Hsa-MiR-6747-3p (LncBase)
- MIMAT0027395 (miRBase)
- MIMAT0027394 (miRBase)
- MI0022592 (miRBase)
- MIR6747 (Ensembl)
External Ids for MIR6747 Gene
- HGNC: 50027
- NCBI Entrez Gene: 102465447
- Ensembl: ENSG00000276102
Previous GeneCards Identifiers for MIR6747 Gene
- GC11U902206
Summaries for MIR6747 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR6747 Gene
MIR6747 (MicroRNA 6747) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR6747 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6747 Gene
Genomics for MIR6747 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR6747 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J062565 | Enhancer | 0.7 | Ensembl dbSUPER | 250.7 | +0.1 | 54 | 2 | ZNF316 ELF1 ZBTB33 IKZF1 HSF1 POLR2A IKZF2 | MIR6747 EML3 ENSG00000255508 TUT1 MTA2 ENSG00000254964 ENSG00000257058 ENSG00000250659 ENSG00000255446 ENSG00000255126 | |
| GH11J062564 | Enhancer | 0.5 | Ensembl dbSUPER | 250.7 | +1.9 | 1870 | 0.4 | ZNF18 SP1 | MIR6747 ENSG00000255508 TUT1 MTA2 ENSG00000254964 EML3 ENSG00000250659 ENSG00000255446 ENSG00000255126 SCGB1A1 | |
| GH11J062569 | Enhancer | 0.3 | dbSUPER | 0.7 | -3.1 | -3121 | 1.7 | SPI1 RBFOX2 | piR-61960-001 EML3 ENSG00000255508 TUT1 MTA2 ENSG00000254964 ENSG00000257058 ENSG00000250659 ENSG00000255446 ENSG00000255126 | |
| GH11J062563 | Enhancer | 0.3 | dbSUPER | 0.7 | +3.1 | 3068 | 0.6 | POLR2A | ENSG00000255508 TUT1 MTA2 ENSG00000254964 EML3 ENSG00000250659 ENSG00000255446 SCGB1A1 ENSG00000255126 ASRGL1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR6747 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR6747 Gene
Latest Assembly
- chr11:62,567,011-62,567,071
- (GRCh38/hg38)
- Size:
- 61 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:62,334,483-62,334,543
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 61 bases
- Orientation:
- Minus strand
Genomic View for MIR6747 Gene
Genes around MIR6747 on UCSC Golden Path with GeneCards custom track
MIR6747 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 11q12.3 by HGNC
- 11q12.3 by Entrez Gene
- 11q12.3 by Ensembl
MIR6747 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR6747 Gene
Proteins for MIR6747 Gene
Post-translational modifications for MIR6747 Gene
No Post-translational modifications
No data available for DME Specific Peptides for MIR6747 Gene
Domains & Families for MIR6747 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6747 Gene
Function for MIR6747 Gene
Phenotypes From GWAS Catalog for MIR6747 Gene
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6747 Gene
Localization for MIR6747 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6747 Gene
Transcripts for MIR6747 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6747 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000075BE67_9606 | pre_miRNA | 61 | 3 |
RefSeq: NR_106805, Ensembl: ENST00000617193 (view in UCSC) , miRBase: MI0022592, |
| URS000075B922_9606 | miRNA | 21 | 3 |
RefSeq: NR_106805, LncBase: hsa-miR-6747-3p, miRBase: MIMAT0027395, |
| URS000075A10C_9606 | miRNA | 24 | 2 |
RefSeq: NR_106805, miRBase: MIMAT0027394, |
MIR6747 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Relevant External Links for MIR6747 Gene
- GeneLoc Exon Structure for
- MIR6747
No data available for mRNA/cDNA for MIR6747 Gene
Expression for MIR6747 Gene
No Expression Related Data Available
Primer products for research
-
OriGene qPCR primer pairs for MIR6747
Gene Expression Assays for research
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6747 Gene
Orthologs for MIR6747 Gene
No data available for Orthologs for MIR6747 Gene
Paralogs for MIR6747 Gene
No data available for Paralogs for MIR6747 Gene
Variants for MIR6747 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for MIR6747 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR6747
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6747 Gene
Disorders for MIR6747 Gene
Additional Disease Information for MIR6747
No disorders were found for MIR6747 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6747 Gene
Publications for MIR6747 Gene
- Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
ExternalLinks
Products for MIR6747 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR6747
- Origene Custom Protein Services for MIR6747
- Browse OriGene Inhibitory RNA Products For MIR6747
- OriGene qPCR primer pairs for MIR6747
- Browse CRISPR knockouts for MIR6747
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR6747
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR6747
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR6747
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR6747
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR6747
Sources for MIR6747 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB