microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6747 Gene

Subcategory (RNA class) for MIR6747 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR6747 Gene

  • MicroRNA 6747 2 3 5
  • MicroRNA Mir-6747 3
  • Hsa-MiR-6747-3p 168
  • Hsa-Mir-6747 3
  • MIMAT0027394 53
  • MIMAT0027395 53
  • MI0022592 53
  • MIR6747 2

External Ids for MIR6747 Gene

Previous GeneCards Identifiers for MIR6747 Gene

  • GC11U902206

Summaries for MIR6747 Gene

Entrez Gene Summary for MIR6747 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6747 Gene

MIR6747 (MicroRNA 6747) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6747 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6747 Gene

Genomics for MIR6747 Gene

GeneHancer (GH) Regulatory Elements for MIR6747 Gene

Promoters and enhancers for MIR6747 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J062565 Enhancer 0.7 Ensembl dbSUPER 750.6 +0.5 470 2.4 POLR2A SP1 HNF1A IKZF1 IKZF2 ZNF316 ELF1 ZBTB33 MIR6747 EML3 ENSG00000255508 TUT1 ENSG00000254964 MTA2 ENSG00000257058 ENSG00000250659 ENSG00000255446 SCGB1A1
GH11J062550 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +10.0 9971 14.2 SIN3A ZBTB40 SP1 CTCF ZBTB6 SMARCE1 POLR2A ZNF217 CREB1 MIXL1 AHNAK EML3 NXF1 MTA2 WDR74 UBXN1 INTS5 CSKMT TUT1 GANAB
GH11J062571 Promoter/Enhancer 0.5 EPDnew dbSUPER 0.6 -4.6 -4572 0.1 EEF1G lnc-TUT1-2 piR-61960-001 MIR6747 ENSG00000255508
GH11J062569 Enhancer 0.2 dbSUPER 0.6 -3.1 -3121 1.7 piR-61960-001 EML3 ENSG00000255508 TUT1 MTA2 ENSG00000254964 ENSG00000257058 ENSG00000250659 ENSG00000255446 SCGB1A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6747 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6747 Gene

Genomic Locations for MIR6747 Gene
chr11:62,567,011-62,567,071
(GRCh38/hg38)
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR6747 Gene

Genes around MIR6747 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6747 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6747 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6747 Gene

Proteins for MIR6747 Gene

Post-translational modifications for MIR6747 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6747 Gene

Domains & Families for MIR6747 Gene

Gene Families for MIR6747 Gene

HGNC:
genes like me logo Genes that share domains with MIR6747: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6747 Gene

Function for MIR6747 Gene

Phenotypes From GWAS Catalog for MIR6747 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6747 Gene

Localization for MIR6747 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6747 Gene

Pathways & Interactions for MIR6747 Gene

PathCards logo

SuperPathways for MIR6747 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6747 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6747 Gene

Drugs & Compounds for MIR6747 Gene

No Compound Related Data Available

Transcripts for MIR6747 Gene

mRNA/cDNA for MIR6747 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(1) LncBase transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6747 Gene

No ASD Table

Relevant External Links for MIR6747 Gene

GeneLoc Exon Structure for
MIR6747
ECgene alternative splicing isoforms for
MIR6747

Expression for MIR6747 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6747 Gene:

MIR6747
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6747 Gene

Orthologs for MIR6747 Gene

Evolution for MIR6747 Gene

ENSEMBL:
Gene Tree for MIR6747 (if available)
TreeFam:
Gene Tree for MIR6747 (if available)

No data available for Orthologs for MIR6747 Gene

Paralogs for MIR6747 Gene

No data available for Paralogs for MIR6747 Gene

Variants for MIR6747 Gene

Sequence variations from dbSNP and Humsavar for MIR6747 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000147208 -- 62,568,791(-) G/A upstream_transcript_variant
rs1000451807 -- 62,567,325(-) G/A/T upstream_transcript_variant
rs1001090242 -- 62,567,094(-) A/C upstream_transcript_variant
rs1001643910 -- 62,568,099(-) G/C upstream_transcript_variant
rs1002074966 -- 62,568,464(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6747 Gene

Variant ID Type Subtype PubMed ID
esv3584599 CNV gain 24956385
nsv347 CNV deletion 18451855
nsv555174 CNV gain 21841781
nsv825939 CNV gain 20364138
nsv832180 CNV loss 17160897
nsv832182 CNV gain+loss 17160897

Additional Variant Information for MIR6747 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6747

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6747 Gene

Disorders for MIR6747 Gene

Additional Disease Information for MIR6747

No disorders were found for MIR6747 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6747 Gene

Publications for MIR6747 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6747 Gene

Sources for MIR6747 Gene