microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6745 Gene

Subcategory (RNA class) for MIR6745 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6745 Gene

  • MicroRNA 6745 2 3 5
  • Hsa-Mir-6745 2 3
  • MIR6745 2 5
  • MicroRNA Mir-6745 3
  • MIMAT0027391 50
  • MI0022590 50

External Ids for MIR6745 Gene

Previous GeneCards Identifiers for MIR6745 Gene

  • GC11U902153
  • GC11M047274
  • GC11M047944
  • GC11M055810
  • GC11M056032
  • GC11M056174
  • GC11M059692
  • GC11M050796
  • GC11M051591
  • GC11M052253
  • GC11M052913
  • GC11M053581
  • GC11M054247
  • GC11M054913
  • GC11M055613

Summaries for MIR6745 Gene

Entrez Gene Summary for MIR6745 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6745 Gene

MIR6745 (MicroRNA 6745) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6745 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6745 Gene

Genomics for MIR6745 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6745 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J047175 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +2.0 1997 4.7 SP1 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 NFKBIZ NFRKB POLR2A ARFGAP2 MIR6745 lnc-PACSIN3-1 NUP160 FNBP4 ENSG00000200090 ENSG00000270060 DDB2 ENSG00000244313 AMBRA1
GH11J047181 Enhancer 0.5 Ensembl dbSUPER 600.7 -1.9 -1864 1.2 BCOR ZMYM3 MIR6745 PACSIN3 LRP4 ENSG00000271350 ARFGAP2
GH11J047182 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -6.6 -6631 8.2 HNRNPL CREB1 GATAD2A ATF7 PRDM10 ZNF629 REST TFE3 NFKBIZ KDM1A PACSIN3 JX952203 FNBP4 NUP160 ENSG00000271350 ENSG00000200090 AMBRA1 ENSG00000270060 CELF1 LRP4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6745 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6745 Gene

Genomic Locations for MIR6745 Gene
chr11:47,179,611-47,179,737
(GRCh38/hg38)
Size:
127 bases
Orientation:
Minus strand

Genomic View for MIR6745 Gene

Genes around MIR6745 on UCSC Golden Path with GeneCards custom track
MIR6745 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6745 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6745 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6745 Gene

Proteins for MIR6745 Gene

Post-translational modifications for MIR6745 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6745 Gene

Domains & Families for MIR6745 Gene

Gene Families for MIR6745 Gene

HGNC:
genes like me logo Genes that share domains with MIR6745: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6745 Gene

Function for MIR6745 Gene

Phenotypes From GWAS Catalog for MIR6745 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6745 Gene

Localization for MIR6745 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6745 Gene

Pathways & Interactions for MIR6745 Gene

PathCards logo

SuperPathways for MIR6745 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6745 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6745 Gene

Drugs & Compounds for MIR6745 Gene

No Compound Related Data Available

Transcripts for MIR6745 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6745 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C2C8_9606 precursor_RNA 127 4

HGNC: 50106,

RefSeq: NR_106803,

Ensembl: ENST00000612694 (view in UCSC) ,

miRBase: MI0022590,

URS000075AE63_9606 miRNA 21 2

RefSeq: NR_106803,

miRBase: MIMAT0027391,

MIR6745 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6745 Gene

No ASD Table

Relevant External Links for MIR6745 Gene

GeneLoc Exon Structure for
MIR6745

No data available for mRNA/cDNA for MIR6745 Gene

Expression for MIR6745 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6745 Gene

Orthologs for MIR6745 Gene

Evolution for MIR6745 Gene

ENSEMBL:
Gene Tree for MIR6745 (if available)
TreeFam:
Gene Tree for MIR6745 (if available)

No data available for Orthologs for MIR6745 Gene

Paralogs for MIR6745 Gene

No data available for Paralogs for MIR6745 Gene

Variants for MIR6745 Gene

Additional dbSNP identifiers (rs#s) for MIR6745 Gene

Additional Variant Information for MIR6745 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6745

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6745 Gene

Disorders for MIR6745 Gene

Additional Disease Information for MIR6745

No disorders were found for MIR6745 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6745 Gene

Publications for MIR6745 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6745 Gene

Sources for MIR6745 Gene