microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6740 Gene

Subcategory (RNA class) for MIR6740 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6740 Gene

  • MicroRNA 6740 2 3 5
  • MicroRNA Mir-6740 3
  • Hsa-Mir-6740 3
  • MIMAT0027381 53
  • MIMAT0027382 53
  • MI0022585 53
  • MIR6740 2

External Ids for MIR6740 Gene

Previous GeneCards Identifiers for MIR6740 Gene

  • GC01U904138

Summaries for MIR6740 Gene

Entrez Gene Summary for MIR6740 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6740 Gene

MIR6740 (MicroRNA 6740) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6740 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6740 Gene

Genomics for MIR6740 Gene

GeneHancer (GH) Regulatory Elements for MIR6740 Gene

Promoters and enhancers for MIR6740 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J202002 Enhancer 0.2 dbSUPER 750.6 +0.2 155 1 MIR6740 RNPEP TNNI1 ELF3 ELF3-AS1
GH01J202004 Enhancer 0.2 Ensembl 750.6 +1.8 1777 0.2 MIR6740 RNPEP ELF3 ELF3-AS1
GH01J202001 Enhancer 0.2 dbSUPER 750.6 -0.9 -937 0.8 MIR6740 RNPEP TIMM17A LMOD1 TNNI1 ELF3-AS1 RF00017-438
GH01J201999 Enhancer 0.9 ENCODE dbSUPER 0.6 -3.3 -3336 0.2 CTCF CC2D1A RAD21 ZSCAN21 IKZF1 PKNOX1 ARID2 RXRA REST ZEB2 ENSG00000224818 LMOD1 GPR37L1 TIMM17A ARL8A PTPN7 MIR6740 RF00017-438 ELF3-AS1 RNPEP
GH01J201990 Enhancer 0.8 VISTA ENCODE 0.4 -12.2 -12209 2.4 ZNF121 RXRA RCOR1 NR2F2 RF00017-438 RNPEP LMOD1 ENSG00000223774 SHISA4 TIMM17A MIR6740
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6740 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6740 Gene

Genomic Locations for MIR6740 Gene
chr1:202,003,124-202,003,236
(GRCh38/hg38)
Size:
113 bases
Orientation:
Plus strand

Genomic View for MIR6740 Gene

Genes around MIR6740 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6740 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6740 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6740 Gene

Proteins for MIR6740 Gene

Post-translational modifications for MIR6740 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6740 Gene

Domains & Families for MIR6740 Gene

Gene Families for MIR6740 Gene

HGNC:
genes like me logo Genes that share domains with MIR6740: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6740 Gene

Function for MIR6740 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6740 Gene

Localization for MIR6740 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6740 Gene

Pathways & Interactions for MIR6740 Gene

PathCards logo

SuperPathways for MIR6740 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6740 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6740 Gene

Drugs & Compounds for MIR6740 Gene

No Compound Related Data Available

Transcripts for MIR6740 Gene

mRNA/cDNA for MIR6740 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6740 Gene

No ASD Table

Relevant External Links for MIR6740 Gene

GeneLoc Exon Structure for
MIR6740
ECgene alternative splicing isoforms for
MIR6740

Expression for MIR6740 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6740 Gene:

MIR6740
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6740 Gene

Orthologs for MIR6740 Gene

Evolution for MIR6740 Gene

ENSEMBL:
Gene Tree for MIR6740 (if available)
TreeFam:
Gene Tree for MIR6740 (if available)

No data available for Orthologs for MIR6740 Gene

Paralogs for MIR6740 Gene

No data available for Paralogs for MIR6740 Gene

Variants for MIR6740 Gene

Sequence variations from dbSNP and Humsavar for MIR6740 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000191631 -- 202,002,151(+) C/A upstream_transcript_variant
rs1002041349 -- 202,001,806(+) G/A upstream_transcript_variant
rs1002044491 -- 202,003,083(+) G/A upstream_transcript_variant
rs1002538030 -- 202,002,066(+) A/G upstream_transcript_variant
rs1006665029 -- 202,001,420(+) G/A upstream_transcript_variant

Additional Variant Information for MIR6740 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6740

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6740 Gene

Disorders for MIR6740 Gene

Additional Disease Information for MIR6740

No disorders were found for MIR6740 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6740 Gene

Publications for MIR6740 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6740 Gene

Sources for MIR6740 Gene