microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6721 Gene

Subcategory (RNA class) for MIR6721 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR6721 Gene

  • MicroRNA 6721 2 3 5
  • Hsa-Mir-6721 2 3
  • MIR6721 2 5
  • MicroRNA Mir-6721 3
  • MIMAT0025852 50
  • MI0022556 50
  • Mir-6721 3

External Ids for MIR6721 Gene

Previous GeneCards Identifiers for MIR6721 Gene

  • GC06U902582

Summaries for MIR6721 Gene

Entrez Gene Summary for MIR6721 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6721 Gene

MIR6721 (MicroRNA 6721) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis.

Additional gene information for MIR6721 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6721 Gene

Genomics for MIR6721 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6721 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J032175 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -7.2 -7244 5.9 ZNF221 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A PRDM10 REST ZNF629 TFE3 RNF5 AGPAT1 DDX39B BRD2 LY6G5B LSM2 ATF6B MSH5 TNXB MICA
GH06J032165 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 0.7 +2.1 2140 4.2 ARHGAP35 HNRNPL CREB1 CTCF PRDM10 LEF1 IKZF1 JUND PRDM1 DDX20 EGFL8 ATF6B RNF5 AGPAT1 SKIV2L DXO MICB HLA-DQA2 HLA-C MIR6721
GH06J032173 Enhancer 0.6 ENCODE dbSUPER 0.7 -3.3 -3253 0.3 ZFHX2 HDAC2 KDM1A ZBTB12 HDAC1 RNF5 AGPAT1 MIR6721 EGFL8 RF00017-5420
GH06J032172 Enhancer 0.5 ENCODE dbSUPER 0.7 -2.9 -2903 0.3 ZFHX2 ZBTB12 ATF6B MIR6721 AGPAT1 EGFL8 RF00017-5420
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6721 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6721 Gene

Genomic Locations for MIR6721 Gene
chr6:32,170,030-32,170,116
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR6721 Gene

Genes around MIR6721 on UCSC Golden Path with GeneCards custom track
MIR6721 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6721 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6721 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for MIR6721 Gene

Post-translational modifications for MIR6721 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6721 Gene

Domains & Families for MIR6721 Gene

Gene Families for MIR6721 Gene

HGNC:
genes like me logo Genes that share domains with MIR6721: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6721 Gene

Function for MIR6721 Gene

Phenotypes From GWAS Catalog for MIR6721 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6721 Gene

Localization for MIR6721 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6721 Gene

Pathways & Interactions for MIR6721 Gene

genes like me logo Genes that share pathways with MIR6721: view

Gene Ontology (GO) - Biological Process for MIR6721 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6721 Gene

Drugs & Compounds for MIR6721 Gene

No Compound Related Data Available

Transcripts for MIR6721 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6721 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D15B_9606 precursor_RNA 87 5

HGNC: 50049,

RefSeq: NR_106779,

Ensembl: ENST00000617181 (view in UCSC) ,

miRBase: MI0022556,

ENA: LM611783.1:1..87:precursor_RNA,

URS000075E1DC_9606 miRNA 23 3

RefSeq: NR_106779,

miRBase: MIMAT0025852,

ENA: LM383138.1:1..23:ncRNA, LM611783.1:11..33:ncRNA,

URS000013DA8D_9606 miRNA 24 1

ENA: JX944781.1:1..24:ncRNA,

MIR6721 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR6721 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6721 Gene

No ASD Table

Relevant External Links for MIR6721 Gene

GeneLoc Exon Structure for
MIR6721

Expression for MIR6721 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6721 Gene

Orthologs for MIR6721 Gene

Evolution for MIR6721 Gene

ENSEMBL:
Gene Tree for MIR6721 (if available)
TreeFam:
Gene Tree for MIR6721 (if available)

No data available for Orthologs for MIR6721 Gene

Paralogs for MIR6721 Gene

No data available for Paralogs for MIR6721 Gene

Variants for MIR6721 Gene

Additional dbSNP identifiers (rs#s) for MIR6721 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6721 Gene

Variant ID Type Subtype PubMed ID
dgv10404n54 CNV loss 21841781
dgv10463n54 CNV loss 21841781
dgv10472n54 CNV loss 21841781
esv2759415 CNV gain+loss 17122850
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1126749 CNV deletion 24896259
nsv602104 CNV loss 21841781
nsv830629 CNV loss 17160897

Additional Variant Information for MIR6721 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6721

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6721 Gene

Disorders for MIR6721 Gene

Additional Disease Information for MIR6721

No disorders were found for MIR6721 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6721 Gene

Publications for MIR6721 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6721 Gene

Sources for MIR6721 Gene