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Aliases for MIR6719 Gene

Subcategory (RNA class) for MIR6719 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6719 Gene

  • MicroRNA 6719 2 3 5
  • MicroRNA Mir-6719 3
  • Hsa-Mir-6719 3

External Ids for MIR6719 Gene

Previous GeneCards Identifiers for MIR6719 Gene

  • GC19U901819

Summaries for MIR6719 Gene

Entrez Gene Summary for MIR6719 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6719 Gene

MIR6719 (MicroRNA 6719) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6719 include Abdominal Obesity-Metabolic Syndrome 3.

Additional gene information for MIR6719 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6719 Gene

Genomics for MIR6719 Gene

GeneHancer (GH) Regulatory Elements for MIR6719 Gene

Promoters and enhancers for MIR6719 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J039827 Enhancer 1 Ensembl ENCODE dbSUPER 600.7 +1.3 1275 1.7 KLF14 PRDM1 IKZF1 ZNF600 ATF2 ELF1 ZBTB17 NR2F1 ZNF366 ZNF664 MIR6719 GC19M040630 DYRK1B
GH19J039830 Enhancer 0.7 ENCODE dbSUPER 600.7 -0.3 -297 0.1 SCRT2 SCRT1 HIC1 SIN3A MIR6719 DYRK1B
GH19J039831 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.7 -3.6 -3648 3.6 SP1 ZFX CBFA2T2 ZNF148 NKRF CSDE1 ZSCAN21 FOS MAFK ZBTB7A DYRK1B HNRNPL SNRPA ZNF780B FBL AKT2 PLEKHG2 ZNF780A RN7SL566P COQ8B
GH19J039823 Enhancer 1.2 ENCODE dbSUPER 0.7 +4.9 4886 2.7 SP1 NKRF ZNF121 ZSCAN21 ZBTB7A YY1 SP7 POLR2A KLF14 CREM GC19M040630 ZNF780B HNRNPL SNRPA ZNF780A AKT2 FBL COQ8B ITPKC PAK4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6719 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6719 Gene

Genomic Locations for MIR6719 Gene
chr19:39,829,716-39,829,802
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR6719 Gene

Genes around MIR6719 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6719 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6719 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6719 Gene

Proteins for MIR6719 Gene

Post-translational modifications for MIR6719 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6719 Gene

Domains & Families for MIR6719 Gene

Gene Families for MIR6719 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6719: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6719 Gene

Function for MIR6719 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6719 Gene

Localization for MIR6719 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6719 Gene

Pathways & Interactions for MIR6719 Gene

PathCards logo

SuperPathways for MIR6719 Gene

No Data Available

Interacting Proteins for MIR6719 Gene

Gene Ontology (GO) - Biological Process for MIR6719 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6719 Gene

Drugs & Compounds for MIR6719 Gene

No Compound Related Data Available

Transcripts for MIR6719 Gene

mRNA/cDNA for MIR6719 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6719 Gene

No ASD Table

Relevant External Links for MIR6719 Gene

GeneLoc Exon Structure for
MIR6719
ECgene alternative splicing isoforms for
MIR6719

Expression for MIR6719 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6719 Gene:

MIR6719
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6719 Gene

Orthologs for MIR6719 Gene

Evolution for MIR6719 Gene

ENSEMBL:
Gene Tree for MIR6719 (if available)
TreeFam:
Gene Tree for MIR6719 (if available)

No data available for Orthologs for MIR6719 Gene

Paralogs for MIR6719 Gene

No data available for Paralogs for MIR6719 Gene

Variants for MIR6719 Gene

Sequence variations from dbSNP and Humsavar for MIR6719 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs367643250 pathogenic, Abdominal obesity-metabolic syndrome 3 39,830,443(-) G/A upstream_transcript_variant
rs587777380 pathogenic, Abdominal obesity-metabolic syndrome 3 39,830,478(-) T/G upstream_transcript_variant
rs1000419586 -- 39,829,288(-) G/A downstream_transcript_variant
rs1000920589 -- 39,830,851(-) G/C upstream_transcript_variant
rs1004441956 -- 39,831,240(-) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6719 Gene

Variant ID Type Subtype PubMed ID
esv2758760 CNV gain 17122850
nsv9725 CNV gain+loss 18304495

Additional Variant Information for MIR6719 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6719

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6719 Gene

Disorders for MIR6719 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6719 Gene - From: GeneCards

Disorder Aliases PubMed IDs
abdominal obesity-metabolic syndrome 3
  • aoms3
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6719

genes like me logo Genes that share disorders with MIR6719: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6719 Gene

Publications for MIR6719 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6719 Gene

Sources for MIR6719 Gene

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