microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6718 Gene

Subcategory (RNA class) for MIR6718 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR6718 Gene

  • MicroRNA 6718 2 3 5
  • MicroRNA Mir-6718 3
  • Hsa-MiR-6718-5p 166
  • Hsa-Mir-6718 3
  • MIMAT0025849 51
  • MI0022553 51
  • MIR6718 2

External Ids for MIR6718 Gene

Previous GeneCards Identifiers for MIR6718 Gene

  • GC18U900829

Summaries for MIR6718 Gene

Entrez Gene Summary for MIR6718 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6718 Gene

MIR6718 (MicroRNA 6718) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6718 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6718 Gene

Genomics for MIR6718 Gene

GeneHancer (GH) Regulatory Elements for MIR6718 Gene

Promoters and enhancers for MIR6718 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J003886 Enhancer 0.6 Ensembl ENCODE 500.7 +1.8 1767 1.2 USF1 MITF TOE1 GATA2 USF2 RAD51 MIR6718 DLGAP1 RNU6-831P RF00026-461 DLGAP1-AS3
GH18J003880 Promoter 0.6 EPDnew 0.4 -5.2 -5249 0.1 GABPA GABPB1 ELF1 piR-50889 DLGAP1 MIR6718 DLGAP1-AS3
GH18J003881 Enhancer 0.3 Ensembl 0.7 -4.4 -4352 1.2 GABPA IKZF1 piR-50889 DLGAP1 MIR6718 DLGAP1-AS3
GH18J003888 Enhancer 0.3 Ensembl 0.7 +4.2 4248 1.6 NFIA FOS DLGAP1 MIR6718 RNU6-831P RF00026-461 DLGAP1-AS3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6718 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6718 Gene

Genomic Locations for MIR6718 Gene
chr18:3,885,353-3,885,432
(GRCh38/hg38)
Size:
80 bases
Orientation:
Plus strand

Genomic View for MIR6718 Gene

Genes around MIR6718 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6718 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6718 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6718 Gene

Proteins for MIR6718 Gene

Post-translational modifications for MIR6718 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6718 Gene

Domains & Families for MIR6718 Gene

Gene Families for MIR6718 Gene

HGNC:
genes like me logo Genes that share domains with MIR6718: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6718 Gene

Function for MIR6718 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6718 Gene

Localization for MIR6718 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6718 Gene

Pathways & Interactions for MIR6718 Gene

PathCards logo

SuperPathways for MIR6718 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR6718 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6718 Gene

Drugs & Compounds for MIR6718 Gene

No Compound Related Data Available

Transcripts for MIR6718 Gene

mRNA/cDNA for MIR6718 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6718 Gene

No ASD Table

Relevant External Links for MIR6718 Gene

GeneLoc Exon Structure for
MIR6718

Expression for MIR6718 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6718 Gene

Orthologs for MIR6718 Gene

Evolution for MIR6718 Gene

ENSEMBL:
Gene Tree for MIR6718 (if available)
TreeFam:
Gene Tree for MIR6718 (if available)

No data available for Orthologs for MIR6718 Gene

Paralogs for MIR6718 Gene

No data available for Paralogs for MIR6718 Gene

Variants for MIR6718 Gene

Additional dbSNP identifiers (rs#s) for MIR6718 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6718 Gene

Variant ID Type Subtype PubMed ID
dgv134e55 CNV gain 17911159
dgv184n21 CNV gain 19592680
esv2758710 CNV gain 17122850
nsv2191 CNV deletion 18451855
nsv833582 CNV loss 17160897

Additional Variant Information for MIR6718 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6718

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6718 Gene

Disorders for MIR6718 Gene

Additional Disease Information for MIR6718

No disorders were found for MIR6718 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6718 Gene

Publications for MIR6718 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6718 Gene

Sources for MIR6718 Gene