microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6716 Gene

Subcategory (RNA class) for MIR6716 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6716 Gene

  • MicroRNA 6716 2 3 5
  • MicroRNA Mir-6716 3
  • Hsa-Mir-6716 3
  • MIMAT0025845 53
  • MIMAT0025844 53
  • MI0022550 53
  • MIR6716 2

External Ids for MIR6716 Gene

Previous GeneCards Identifiers for MIR6716 Gene

  • GC11U902172
  • GC11P118607

Summaries for MIR6716 Gene

Entrez Gene Summary for MIR6716 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6716 Gene

MIR6716 (MicroRNA 6716) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6716 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6716 Gene

Genomics for MIR6716 Gene

GeneHancer (GH) Regulatory Elements for MIR6716 Gene

Promoters and enhancers for MIR6716 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J118642 Enhancer 0.8 ENCODE dbSUPER 750.6 -0.8 -754 1 L3MBTL2 ATF1 HDAC1 ZNF316 NCOR1 CREM BCOR PTBP1 DPF2 ZNF592 MIR6716 ENSG00000255422 ARCN1 ENSG00000254428 ENSG00000254909 DPAGT1 RPL23AP64 BCL9L TREH MPZL2
GH11J118640 Enhancer 1 Ensembl ENCODE dbSUPER 0.6 -2.3 -2298 1.5 CTCF MNT MTA3 NFIB MYC PRDM1 TARDBP CTBP1 E4F1 ZNF512B TREHP1 ENSG00000255422 HINFP VPS11 KMT2A CCDC84 RNF26 RPL5P30 TREH PHLDB1
GH11J118658 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +15.8 15800 3.2 CTCF CC2D1A RAD21 SP1 ZBTB33 ELF3 AHR SP5 MTA1 IKZF1 TREHP1 TREH IFT46 lnc-TREH-1 MIR6716
GH11J118678 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 0.3 +35.5 35494 1.5 MLX CTCF SP1 TFE3 ZNF644 IKZF1 RXRA GATAD2A IRF2 SOX13 TREH lnc-TREH-1 TREHP1 MIR6716
GH11J118662 Enhancer 0.9 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +19.0 19001 1.2 ZIC2 DPF2 CTCF TREH lnc-TREH-1 MIR6716
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6716 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6716 Gene

Genomic Locations for MIR6716 Gene
chr11:118,644,000-118,644,079
(GRCh38/hg38)
Size:
80 bases
Orientation:
Plus strand

Genomic View for MIR6716 Gene

Genes around MIR6716 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6716 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6716 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6716 Gene

Proteins for MIR6716 Gene

Post-translational modifications for MIR6716 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6716 Gene

Domains & Families for MIR6716 Gene

Gene Families for MIR6716 Gene

HGNC:
genes like me logo Genes that share domains with MIR6716: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6716 Gene

Function for MIR6716 Gene

Phenotypes From GWAS Catalog for MIR6716 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6716 Gene

Localization for MIR6716 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6716 Gene

Pathways & Interactions for MIR6716 Gene

PathCards logo

SuperPathways for MIR6716 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6716 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6716 Gene

Drugs & Compounds for MIR6716 Gene

No Compound Related Data Available

Transcripts for MIR6716 Gene

mRNA/cDNA for MIR6716 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6716 Gene

No ASD Table

Relevant External Links for MIR6716 Gene

GeneLoc Exon Structure for
MIR6716
ECgene alternative splicing isoforms for
MIR6716

Expression for MIR6716 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6716 Gene:

MIR6716
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6716 Gene

Orthologs for MIR6716 Gene

Evolution for MIR6716 Gene

ENSEMBL:
Gene Tree for MIR6716 (if available)
TreeFam:
Gene Tree for MIR6716 (if available)

No data available for Orthologs for MIR6716 Gene

Paralogs for MIR6716 Gene

No data available for Paralogs for MIR6716 Gene

Variants for MIR6716 Gene

Sequence variations from dbSNP and Humsavar for MIR6716 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000006153 -- 118,642,106(+) G/A upstream_transcript_variant
rs1004207147 -- 118,644,420(+) G/A downstream_transcript_variant
rs1008421116 -- 118,643,164(+) G/A upstream_transcript_variant
rs1010944838 -- 118,642,059(+) C/T upstream_transcript_variant
rs1015528005 -- 118,644,439(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6716 Gene

Variant ID Type Subtype PubMed ID
nsv527864 CNV loss 19592680
nsv832283 CNV loss 17160897

Additional Variant Information for MIR6716 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6716

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6716 Gene

Disorders for MIR6716 Gene

Additional Disease Information for MIR6716

No disorders were found for MIR6716 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6716 Gene

Publications for MIR6716 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR6716 Gene

Sources for MIR6716 Gene