microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR670 Gene

Subcategory (RNA class) for MIR670 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR670 Gene

  • MicroRNA 670 2 3 5
  • Hsa-Mir-670 2 3 178
  • MIR670 2 5
  • Hsa-MiR-670-5p 173
  • MIMAT0010357 50
  • MIMAT0026640 50
  • MI0003933 50

External Ids for MIR670 Gene

Previous GeneCards Identifiers for MIR670 Gene

  • GC00U928193
  • GC11P043583
  • GC11P043291
  • GC11P043584
  • GC11P043585
  • GC11P043564
  • GC11P043565
  • GC11P043610
  • GC11P043622
  • GC11P043619
  • GC11P043629
  • GC11P043567
  • GC11P043570
  • GC11P043573
  • GC11P043576
  • GC11P043589
  • GC11P043599
  • GC11P043603
  • GC11P043608

Summaries for MIR670 Gene

Entrez Gene Summary for MIR670 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR670 Gene

MIR670 (MicroRNA 670) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR670 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR670 Gene

Genomics for MIR670 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR670 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J043833 Enhancer 0.9 Ensembl ENCODE CraniofacialAtlas 10.4 +274.7 274676 2.3 RFX1 POLR2A CEBPA RFX3 CEBPB FOXA2 FEZF1 GATA2 SPI1 LOC107984328 HSD17B12 MIR670HG MIR670 ALKBH3-AS1 MIR129-2 NONHSAG008131.2 ENSG00000283375 ALKBH3 ENSG00000246250
GH11J043817 Enhancer 0.7 Ensembl ENCODE 10.4 +259.2 259216 2.6 PKNOX1 HMBOX1 BATF TBX21 NFE2 MTA2 MLLT1 HSD17B12 ALKBH3 ENSG00000246250 MIR670HG MIR670 MIR129-2 piR-56341-026 NONHSAG008131.2 ENSG00000283341
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR670 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR670 Gene

Genomic Locations for MIR670 Gene
chr11:43,559,656-43,559,753
(GRCh38/hg38)
Size:
98 bases
Orientation:
Plus strand
chr11:43,581,206-43,581,303
(GRCh37/hg19)
Size:
98 bases
Orientation:
Plus strand

Genomic View for MIR670 Gene

Genes around MIR670 on UCSC Golden Path with GeneCards custom track
MIR670 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR670 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR670 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR670 Gene

Proteins for MIR670 Gene

Post-translational modifications for MIR670 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR670 Gene

Domains & Families for MIR670 Gene

Gene Families for MIR670 Gene

HGNC:
genes like me logo Genes that share domains with MIR670: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR670 Gene

Function for MIR670 Gene

Phenotypes From GWAS Catalog for MIR670 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR670 Gene

Localization for MIR670 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR670 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR670 Gene

Pathways & Interactions for MIR670 Gene

PathCards logo

SuperPathways for MIR670 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR670 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR670 Gene

Drugs & Compounds for MIR670 Gene

No Compound Related Data Available

Transcripts for MIR670 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR670 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B3C7_9606 precursor_RNA 98 4

HGNC: 37304,

RefSeq: NR_031577,

Ensembl: ENST00000390142 (view in UCSC) ,

miRBase: MI0003933,

URS000075D4D2_9606 miRNA 20 3

RefSeq: NR_031577,

miRBase: MIMAT0010357,

TarBase: hsa-miR-670-5p,

URS000075EF30_9606 miRNA 21 2

RefSeq: NR_031577,

miRBase: MIMAT0026640,

URS0000EFF59A_9606 precursor_RNA 65 1

MirGeneDB: Hsa-Mir-670,

URS0000D5602A_9606 miRNA 25 1

MirGeneDB: Hsa-Mir-670_3p,

MIR670 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR670 Gene

No ASD Table

Relevant External Links for MIR670 Gene

GeneLoc Exon Structure for
MIR670

No data available for mRNA/cDNA for MIR670 Gene

Expression for MIR670 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR670 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR670

genes like me logo Genes that share expression patterns with MIR670: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR670 Gene

Orthologs for MIR670 Gene

Evolution for MIR670 Gene

ENSEMBL:
Gene Tree for MIR670 (if available)
TreeFam:
Gene Tree for MIR670 (if available)

No data available for Orthologs for MIR670 Gene

Paralogs for MIR670 Gene

No data available for Paralogs for MIR670 Gene

Variants for MIR670 Gene

Additional dbSNP identifiers (rs#s) for MIR670 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR670 Gene

Variant ID Type Subtype PubMed ID
dgv66n21 CNV loss 19592680

Additional Variant Information for MIR670 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR670

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR670 Gene

Disorders for MIR670 Gene

Additional Disease Information for MIR670

No disorders were found for MIR670 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR670 Gene

Publications for MIR670 Gene

  1. Distinct miRNA signatures associate with subtypes of cholangiocarcinoma from infection with the tumourigenic liver fluke Opisthorchis viverrini. (PMID: 25017828) Plieskatt JL … Bethony JM (Journal of hepatology 2014) 3
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3
  3. miRNAminer: a tool for homologous microRNA gene search. (PMID: 18215311) Artzi S … Shomron N (BMC bioinformatics 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
  5. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E … Cuppen E (Genome research 2006) 3

Products for MIR670 Gene

Sources for MIR670 Gene