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Aliases for MIR656 Gene

Subcategory (RNA class) for MIR656 Gene


Quality Score for this RNA gene is


Aliases for MIR656 Gene

  • MicroRNA 656 2 3 5
  • Hsa-Mir-656 3
  • Mir-656 3
  • MIRN656 3

External Ids for MIR656 Gene

ORGUL Members for MIR656 Gene

Previous HGNC Symbols for MIR656 Gene

  • MIRN656

Previous GeneCards Identifiers for MIR656 Gene

  • GC14P100844
  • GC14P100934
  • GC14P101535
  • GC14P101563
  • GC14P101596
  • GC14P101635
  • GC14P101663
  • GC14P101698
  • GC14P101735
  • GC14P101775
  • GC14P101833
  • GC14P101973
  • GC14P102170
  • GC14P101277
  • GC14P101896
  • GC14P103643
  • GC14P102210
  • GC14P102377
  • GC14P102557
  • GC14P102729
  • GC14P102899
  • GC14P103075
  • GC14P103271
  • GC14P103460

Summaries for MIR656 Gene

Entrez Gene Summary for MIR656 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR656 Gene

MIR656 (MicroRNA 656) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR656 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR656 Gene

Genomics for MIR656 Gene

GeneHancer (GH) Regulatory Elements for MIR656 Gene

Promoters and enhancers for MIR656 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J101096 Enhancer 0.9 FANTOM5 Ensembl ENCODE 11.4 +31.6 31624 3.2 MAFK JUN POLR2A RTL1 ENSG00000230805 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
GH14J101095 Enhancer 0.2 Ensembl 11.4 +29.0 28977 0.6 RTL1 MIR410 MIR656 MEG9 MIR369 MIR409 MIR412 MIR541 MIR377 MIR154
GH14J101070 Promoter/Enhancer 1.5 Ensembl ENCODE 0.4 +6.6 6635 4.9 ZNF148 ZSCAN21 MAFK ZBTB7A ELF1 SP7 EGR1 FOSL2 CREB1 GLIS2 GC14P104053 MEG9 ENSG00000230805 LOC105370670 GC14M101071 MIR656
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR656 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR656 Gene

Genomic Locations for MIR656 Gene
78 bases
Plus strand
78 bases
Plus strand

Genomic View for MIR656 Gene

Genes around MIR656 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR656 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR656 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR656 Gene

Proteins for MIR656 Gene

Post-translational modifications for MIR656 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR656 Gene

Domains & Families for MIR656 Gene

Gene Families for MIR656 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR656: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR656 Gene

Function for MIR656 Gene

Phenotypes From GWAS Catalog for MIR656 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR656 Gene

Localization for MIR656 Gene

Gene Ontology (GO) - Cellular Components for MIR656 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035068 micro-ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with MIR656: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR656 Gene

Pathways & Interactions for MIR656 Gene

PathCards logo

SuperPathways for MIR656 Gene

No Data Available

Interacting Proteins for MIR656 Gene

Gene Ontology (GO) - Biological Process for MIR656 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR656: view

No data available for Pathways by source and SIGNOR curated interactions for MIR656 Gene

Drugs & Compounds for MIR656 Gene

No Compound Related Data Available

Transcripts for MIR656 Gene

mRNA/cDNA for MIR656 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR656 Gene

No ASD Table

Relevant External Links for MIR656 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR656 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR656 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR656 Gene:

genes like me logo Genes that share expression patterns with MIR656: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR656 Gene

Orthologs for MIR656 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR656 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-656 35
  • 100 (a)
(Canis familiaris)
Mammalia -- 35
  • 95 (a)
(Bos Taurus)
Mammalia bta-mir-656 35
  • 95 (a)
(Mus musculus)
Mammalia Mir382 35
  • 50 (a)
Species where no ortholog for MIR656 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR656 Gene

Gene Tree for MIR656 (if available)
Gene Tree for MIR656 (if available)

Paralogs for MIR656 Gene

No data available for Paralogs for MIR656 Gene

Variants for MIR656 Gene

Sequence variations from dbSNP and Humsavar for MIR656 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000697312 -- 101,066,260(+) G/C upstream_transcript_variant
rs1003049499 -- 101,065,113(+) G/T upstream_transcript_variant
rs1003932318 -- 101,064,797(+) C/T upstream_transcript_variant
rs1004937700 -- 101,065,745(+) G/A upstream_transcript_variant
rs1006160079 -- 101,064,852(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR656 Gene

Variant ID Type Subtype PubMed ID
nsv1040993 CNV gain 25217958
nsv509551 CNV insertion 20534489
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR656 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR656 Gene

Disorders for MIR656 Gene

Additional Disease Information for MIR656

No disorders were found for MIR656 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR656 Gene

Publications for MIR656 Gene

  1. miR-656 inhibits glioma tumorigenesis through repression of BMPR1A. (PMID: 24480809) Guo M … Lin Z (Carcinogenesis 2014) 3 58
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  3. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S … Sun J (Carcinogenesis 2012) 3 58
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR656 Gene

Sources for MIR656 Gene

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