microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR655 Gene

Subcategory (RNA class) for MIR655 Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR655 Gene

  • MicroRNA 655 2 3 5
  • Hsa-Mir-655 2 3
  • MIR655 2 5
  • Hsa-Mir-154-P24 178
  • Hsa-MiR-655-3p 173
  • MIMAT0003331 50
  • MIMAT0026626 50
  • MI0003677 50
  • MIRN655 3
  • Mir-655 3
  • RF00641 168

External Ids for MIR655 Gene

Previous HGNC Symbols for MIR655 Gene

  • MIRN655

Previous GeneCards Identifiers for MIR655 Gene

  • GC14P100829
  • GC14P100919
  • GC14P101520
  • GC14P101549
  • GC14P101584
  • GC14P101623
  • GC14P101651
  • GC14P101684
  • GC14P101721
  • GC14P101763
  • GC14P101821
  • GC14P101961
  • GC14P102158
  • GC14P101261
  • GC14P101872
  • GC14P103642
  • GC14P103861
  • GC14P104137
  • GC14P104478
  • GC14P102192
  • GC14P102360
  • GC14P102531
  • GC14P102710
  • GC14P102883
  • GC14P103056
  • GC14P103254
  • GC14P103459

Summaries for MIR655 Gene

Entrez Gene Summary for MIR655 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR655 Gene

MIR655 (MicroRNA 655) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR655 include Pelvic Lipomatosis.

Rfam classification for MIR655 Gene

Additional gene information for MIR655 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR655 Gene

Genomics for MIR655 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR655 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR655 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR655 Gene

Genomic Locations for MIR655 Gene
chr14:101,049,550-101,049,646
(GRCh38/hg38)
Size:
97 bases
Orientation:
Plus strand
chr14:101,515,887-101,515,983
(GRCh37/hg19)
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR655 Gene

Genes around MIR655 on UCSC Golden Path with GeneCards custom track
MIR655 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR655 Gene

Proteins for MIR655 Gene

Post-translational modifications for MIR655 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR655 Gene

Domains & Families for MIR655 Gene

Gene Families for MIR655 Gene

genes like me logo Genes that share domains with MIR655: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR655 Gene

Function for MIR655 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR655 Gene

Localization for MIR655 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR655 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR655 Gene

Pathways & Interactions for MIR655 Gene

PathCards logo

SuperPathways for MIR655 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR655 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR655: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR655 Gene

Drugs & Compounds for MIR655 Gene

No Compound Related Data Available

Transcripts for MIR655 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR655 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B3AB_9606 precursor_RNA 97 5

HGNC: 32911,

RefSeq: NR_030391,

Ensembl: ENST00000362159 (view in UCSC) ,

miRBase: MI0003677,

ENA: LM609596.1:1..97:precursor_RNA,

URS00005E1A16_9606 miRNA 22 5

RefSeq: NR_030391,

miRBase: MIMAT0003331,

MirGeneDB: Hsa-Mir-154-P24_3p,

TarBase: hsa-miR-655-3p,

ENA: LM379893.1:1..22:ncRNA, LM609596.1:61..82:ncRNA,

URS000075AA28_9606 miRNA 22 4

RefSeq: NR_030391,

miRBase: MIMAT0026626,

MirGeneDB: Hsa-Mir-154-P24_5p,

ENA: LM609596.1:23..44:ncRNA,

URS00006AAB22_9606 precursor_RNA 80 1

Rfam: RF00641,

URS0000EFCE5C_9606 precursor_RNA 61 1

MirGeneDB: Hsa-Mir-154-P24,

MIR655 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR655 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR655 Gene

No ASD Table

Relevant External Links for MIR655 Gene

GeneLoc Exon Structure for
MIR655

Expression for MIR655 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR655 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR655

genes like me logo Genes that share expression patterns with MIR655: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR655 Gene

Orthologs for MIR655 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR655 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-655 31
  • 98 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia -- 31
  • 93 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia bta-mir-655 31
  • 93 (a)
OneToOne
Species where no ortholog for MIR655 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR655 Gene

ENSEMBL:
Gene Tree for MIR655 (if available)
TreeFam:
Gene Tree for MIR655 (if available)

Paralogs for MIR655 Gene

No data available for Paralogs for MIR655 Gene

Variants for MIR655 Gene

Additional dbSNP identifiers (rs#s) for MIR655 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR655 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR655 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR655

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR655 Gene

Disorders for MIR655 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR655 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pelvic lipomatosis
  • excess of mature unencapsulated fatty tissue in the pelvis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR655

genes like me logo Genes that share disorders with MIR655: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR655 Gene

Publications for MIR655 Gene

  1. MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lip. (PMID: 31122291) Gajera M … Iwata J (BMC medical genomics 2019) 3
  2. miR526b and miR655 Induce Oxidative Stress in Breast Cancer. (PMID: 31430859) Shin B … Majumder M (International journal of molecular sciences 2019) 3
  3. Low levels of tumour suppressor miR-655 in plasma contribute to lymphatic progression and poor outcomes in oesophageal squamous cell carcinoma. (PMID: 30609933) Kiuchi J … Otsuji E (Molecular cancer 2019) 3
  4. MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2. (PMID: 28990842) Awortwe C … Bruckmueller H (Xenobiotica; the fate of foreign compounds in biological systems 2018) 3
  5. MicroRNA-655 attenuates the malignant biological behaviours of retinoblastoma cells by directly targeting PAX6 and suppressing the ERK and p38 MAPK signalling pathways. (PMID: 29436689) Zhang M … Yin H (Oncology reports 2018) 3

Products for MIR655 Gene

Sources for MIR655 Gene