microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6515 Gene

Subcategory (RNA class) for MIR6515 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR6515 Gene

  • MicroRNA 6515 2 3 5
  • Hsa-Mir-6515 2 3
  • MIR6515 2 5
  • MicroRNA Mir-6515 3
  • MIMAT0025486 50
  • MIMAT0025487 50
  • MI0022227 50
  • Mir-6515 3

External Ids for MIR6515 Gene

Previous GeneCards Identifiers for MIR6515 Gene

  • GC19U901830

Summaries for MIR6515 Gene

Entrez Gene Summary for MIR6515 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6515 Gene

MIR6515 (MicroRNA 6515) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6515 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6515 Gene

Genomics for MIR6515 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6515 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J012936 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -1.4 -1352 5.8 SP1 HNRNPL CREB1 GATAD2A PRDM10 ZNF629 TFE3 ZNF512 LEF1 SOX13 CALR NONHSAG024912.2 MIR6515 ZNF625 ZNF136 TRMT1 RPS6P25 ZNF844 ZNF442 ZNF788P
GH19J012942 Enhancer 0.5 ENCODE 0.7 +2.5 2498 0.2 PRDM10 CEBPB ZNF189 ATF4 ATF3 POLR2A ZNF362 ENSG00000267458 CALR RAD23A MIR6515
GH19J012944 Enhancer 0.5 ENCODE 0.7 +2.0 2027 0.5 RBFOX2 POLR2A CEBPB ZNF189 ATF4 ATF3 PML ENSG00000267458 GCDH CALR RAD23A MIR6515
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6515 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6515 Gene

Genomic Locations for MIR6515 Gene
chr19:12,940,484-12,940,540
(GRCh38/hg38)
Size:
57 bases
Orientation:
Plus strand

Genomic View for MIR6515 Gene

Genes around MIR6515 on UCSC Golden Path with GeneCards custom track
MIR6515 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6515 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6515 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6515 Gene

Proteins for MIR6515 Gene

Post-translational modifications for MIR6515 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6515 Gene

Domains & Families for MIR6515 Gene

Gene Families for MIR6515 Gene

HGNC:
genes like me logo Genes that share domains with MIR6515: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6515 Gene

Function for MIR6515 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6515 Gene

Localization for MIR6515 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6515 Gene

Pathways & Interactions for MIR6515 Gene

PathCards logo

SuperPathways for MIR6515 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6515 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6515 Gene

Drugs & Compounds for MIR6515 Gene

No Compound Related Data Available

Transcripts for MIR6515 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6515 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CDB4_9606 precursor_RNA 57 5

HGNC: 50227,

RefSeq: NR_106770,

Ensembl: ENST00000619843 (view in UCSC) ,

miRBase: MI0022227,

ENA: LM611753.1:1..57:precursor_RNA,

URS000075EAB6_9606 miRNA 21 3

RefSeq: NR_106770,

miRBase: MIMAT0025486,

ENA: LM383126.1:1..21:ncRNA, LM611753.1:3..23:ncRNA,

URS000075BDA4_9606 miRNA 20 3

RefSeq: NR_106770,

miRBase: MIMAT0025487,

ENA: LM611753.1:38..57:ncRNA,

MIR6515 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR6515 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6515 Gene

No ASD Table

Relevant External Links for MIR6515 Gene

GeneLoc Exon Structure for
MIR6515

Expression for MIR6515 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6515 Gene

Orthologs for MIR6515 Gene

Evolution for MIR6515 Gene

ENSEMBL:
Gene Tree for MIR6515 (if available)
TreeFam:
Gene Tree for MIR6515 (if available)

No data available for Orthologs for MIR6515 Gene

Paralogs for MIR6515 Gene

No data available for Paralogs for MIR6515 Gene

Variants for MIR6515 Gene

Additional dbSNP identifiers (rs#s) for MIR6515 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6515 Gene

Variant ID Type Subtype PubMed ID
nsv1160589 CNV duplication 26073780
nsv833754 CNV loss 17160897
nsv953977 CNV deletion 24416366

Additional Variant Information for MIR6515 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6515

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6515 Gene

Disorders for MIR6515 Gene

Additional Disease Information for MIR6515

No disorders were found for MIR6515 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6515 Gene

Publications for MIR6515 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6515 Gene

Sources for MIR6515 Gene