microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6511B2 Gene

Subcategory (RNA class) for MIR6511B2 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR6511B2 Gene

  • MicroRNA 6511b-2 2 3 5
  • Hsa-Mir-6511b-2 2 3
  • MIR6511B2 2 5
  • MicroRNA Mir-6511b-2 3
  • Hsa-MiR-6511b-3p 163
  • MIMAT0025847 50
  • MIMAT0025848 50
  • Mir-6511b-2 3
  • MIR6511B-2 3
  • MI0023431 50

External Ids for MIR6511B2 Gene

Previous GeneCards Identifiers for MIR6511B2 Gene

  • GC16U901700

Summaries for MIR6511B2 Gene

Entrez Gene Summary for MIR6511B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6511B2 Gene

MIR6511B2 (MicroRNA 6511b-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6511B2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6511B2 Gene

Genomics for MIR6511B2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6511B2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J015135 Enhancer 0.2 Ensembl 600.7 -1.5 -1456 0.4 MIR6511B2 piR-34295-001 lnc-RRN3-5 PKD1P6 RRN3 PDXDC1 NPIPA5
GH16J015133 Enhancer 0.2 Ensembl 600.7 +0.6 644 0.2 PKD1P6-NPIPP1 MIR6511B2 lnc-RRN3-4 piR-51780-002 PKD1P6 RRN3 PDXDC1 NPIPA5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6511B2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6511B2 Gene

Genomic Locations for MIR6511B2 Gene
chr16:15,134,075-15,134,145
(GRCh38/hg38)
Size:
71 bases
Orientation:
Minus strand

Genomic View for MIR6511B2 Gene

Genes around MIR6511B2 on UCSC Golden Path with GeneCards custom track
MIR6511B2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6511B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6511B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6511B2 Gene

Proteins for MIR6511B2 Gene

Post-translational modifications for MIR6511B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6511B2 Gene

Domains & Families for MIR6511B2 Gene

Gene Families for MIR6511B2 Gene

HGNC:
genes like me logo Genes that share domains with MIR6511B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6511B2 Gene

Function for MIR6511B2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6511B2 Gene

Localization for MIR6511B2 Gene

Gene Ontology (GO) - Cellular Components for MIR6511B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR6511B2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR6511B2 Gene

Pathways & Interactions for MIR6511B2 Gene

PathCards logo

SuperPathways for MIR6511B2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6511B2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6511B2 Gene

Drugs & Compounds for MIR6511B2 Gene

No Compound Related Data Available

Transcripts for MIR6511B2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6511B2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000079AEF9_9606 precursor_RNA 71 5

HGNC: 50230,

RefSeq: NR_106965,

Ensembl: ENST00000636908 (view in UCSC) ,

miRBase: MI0023431,

ENA: LM611788.1:1..71:precursor_RNA,

URS0000759CCE_9606 miRNA 23 4

RefSeq: NR_106775, NR_106965,

LncBase: hsa-miR-6511b-3p,

miRBase: MIMAT0025848,

ENA: LM383136.1:1..23:ncRNA, LM611781.1:53..75:ncRNA, LM611788.1:48..70:ncRNA,

URS0000759A05_9606 miRNA 24 3

RefSeq: NR_106775, NR_106965,

miRBase: MIMAT0025847,

ENA: LM383135.1:1..24:ncRNA, LM611781.1:11..34:ncRNA, LM611788.1:6..29:ncRNA,

URS000042719A_9606 miRNA 24 1

ENA: AB372659.1:1..24:ncRNA,

MIR6511B2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR6511B2 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6511B2 Gene

No ASD Table

Relevant External Links for MIR6511B2 Gene

GeneLoc Exon Structure for
MIR6511B2

Expression for MIR6511B2 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6511B2 Gene

Orthologs for MIR6511B2 Gene

Evolution for MIR6511B2 Gene

ENSEMBL:
Gene Tree for MIR6511B2 (if available)
TreeFam:
Gene Tree for MIR6511B2 (if available)

No data available for Orthologs for MIR6511B2 Gene

Paralogs for MIR6511B2 Gene

No data available for Paralogs for MIR6511B2 Gene

Variants for MIR6511B2 Gene

Additional dbSNP identifiers (rs#s) for MIR6511B2 Gene

Additional Variant Information for MIR6511B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6511B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6511B2 Gene

Disorders for MIR6511B2 Gene

Additional Disease Information for MIR6511B2

No disorders were found for MIR6511B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6511B2 Gene

Publications for MIR6511B2 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  2. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6511B2 Gene

Sources for MIR6511B2 Gene