microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6509 Gene

Subcategory (RNA class) for MIR6509 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR6509 Gene

  • MicroRNA 6509 2 3 5
  • MicroRNA Mir-6509 3
  • Hsa-MiR-6509-3p 166
  • Hsa-Mir-6509 3
  • MIMAT0025475 51
  • MIMAT0025474 51
  • MI0022221 51
  • MIR6509 2

External Ids for MIR6509 Gene

Previous GeneCards Identifiers for MIR6509 Gene

  • GC07U903807

Summaries for MIR6509 Gene

Entrez Gene Summary for MIR6509 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6509 Gene

MIR6509 (MicroRNA 6509) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6509 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6509 Gene

Genomics for MIR6509 Gene

GeneHancer (GH) Regulatory Elements for MIR6509 Gene

Promoters and enhancers for MIR6509 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J135206 Enhancer 0.9 ENCODE dbSUPER 500.7 0.0 0 1.6 EP300 JUND BCL11A ARNT MEF2B SMARCA5 BATF IRF1 IRF4 IKZF1 MIR6509 lnc-C7orf49-4 ENSG00000231794 WDR91 STRA8 CYREN TMEM140 AGBL3
GH07J135203 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.7 +2.4 2394 3.1 NR2F2 ZBTB17 FOS BHLHE40 USF2 MLLT1 ENSG00000231794 STRA8 WDR91 AGBL3 CYREN MIR6509 lnc-C7orf49-4
GH07J135199 Enhancer 0.7 Ensembl 0.4 +6.7 6677 2 ZSCAN5C OSR2 KLF9 WT1 ZBTB17 KLF8 ZFHX2 STAT3 ZNF335 IKZF3 ENSG00000231794 WDR91 MIR6509 lnc-C7orf49-4
GH07J135201 Enhancer 0.4 Ensembl 0.4 +5.4 5377 0.2 ZNF316 MAFF MAFK MAFG EMSY ENSG00000231794 MIR6509 WDR91 lnc-C7orf49-4
GH07J135202 Enhancer 0.2 Ensembl 0.7 +4.6 4577 0.2 STRA8 AGBL3 ENSG00000231794 MIR6509 lnc-C7orf49-4 WDR91
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6509 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6509 Gene

Genomic Locations for MIR6509 Gene
chr7:135,206,994-135,207,078
(GRCh38/hg38)
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR6509 Gene

Genes around MIR6509 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6509 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6509 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6509 Gene

Proteins for MIR6509 Gene

Post-translational modifications for MIR6509 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6509 Gene

Domains & Families for MIR6509 Gene

Gene Families for MIR6509 Gene

HGNC:
genes like me logo Genes that share domains with MIR6509: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6509 Gene

Function for MIR6509 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6509 Gene

Localization for MIR6509 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6509 Gene

Pathways & Interactions for MIR6509 Gene

PathCards logo

SuperPathways for MIR6509 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR6509 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6509 Gene

Drugs & Compounds for MIR6509 Gene

No Compound Related Data Available

Transcripts for MIR6509 Gene

mRNA/cDNA for MIR6509 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
1 LncBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6509 Gene

No ASD Table

Relevant External Links for MIR6509 Gene

GeneLoc Exon Structure for
MIR6509

Expression for MIR6509 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6509 Gene

Orthologs for MIR6509 Gene

Evolution for MIR6509 Gene

ENSEMBL:
Gene Tree for MIR6509 (if available)
TreeFam:
Gene Tree for MIR6509 (if available)

No data available for Orthologs for MIR6509 Gene

Paralogs for MIR6509 Gene

No data available for Paralogs for MIR6509 Gene

Variants for MIR6509 Gene

Additional dbSNP identifiers (rs#s) for MIR6509 Gene

Additional Variant Information for MIR6509 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6509

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6509 Gene

Disorders for MIR6509 Gene

Additional Disease Information for MIR6509

No disorders were found for MIR6509 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6509 Gene

Publications for MIR6509 Gene

  1. Deep sequencing analysis of small non-coding RNAs reveals the diversity of microRNAs and piRNAs in the human epididymis. (PMID: 22313525) Li Y … Li JY (Gene 2012) 3 54
  2. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6509 Gene

Sources for MIR6509 Gene