microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6505 Gene

Subcategory (RNA class) for MIR6505 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR6505 Gene

  • MicroRNA 6505 2 3 5
  • Hsa-Mir-6505 2 3
  • MIR6505 2 5
  • MicroRNA Mir-6505 3
  • MIMAT0025466 50
  • MIMAT0025467 50
  • MI0022217 50
  • Mir-6505 3

External Ids for MIR6505 Gene

Previous GeneCards Identifiers for MIR6505 Gene

  • GC12U901961

Summaries for MIR6505 Gene

Entrez Gene Summary for MIR6505 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6505 Gene

MIR6505 (MicroRNA 6505) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6505 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6505 Gene

Genomics for MIR6505 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6505 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6505 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6505 Gene

Genomic Locations for MIR6505 Gene
chr12:48,132,797-48,132,867
(GRCh38/hg38)
Size:
71 bases
Orientation:
Plus strand

Genomic View for MIR6505 Gene

Genes around MIR6505 on UCSC Golden Path with GeneCards custom track
MIR6505 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6505 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6505 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6505 Gene

Proteins for MIR6505 Gene

Post-translational modifications for MIR6505 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6505 Gene

Domains & Families for MIR6505 Gene

Gene Families for MIR6505 Gene

HGNC:
genes like me logo Genes that share domains with MIR6505: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6505 Gene

Function for MIR6505 Gene

Phenotypes From GWAS Catalog for MIR6505 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6505 Gene

Localization for MIR6505 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6505 Gene

Pathways & Interactions for MIR6505 Gene

PathCards logo

SuperPathways for MIR6505 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6505 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6505 Gene

Drugs & Compounds for MIR6505 Gene

No Compound Related Data Available

Transcripts for MIR6505 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6505 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D860_9606 precursor_RNA 71 5

HGNC: 50104,

RefSeq: NR_106760,

Ensembl: ENST00000617206 (view in UCSC) ,

miRBase: MI0022217,

ENA: LM611746.1:1..71:precursor_RNA,

URS000075D8DA_9606 miRNA 22 3

RefSeq: NR_106760,

miRBase: MIMAT0025466,

ENA: LM383118.1:1..22:ncRNA, LM611746.1:4..25:ncRNA,

URS000075DED1_9606 miRNA 21 3

RefSeq: NR_106760,

miRBase: MIMAT0025467,

ENA: LM611746.1:51..71:ncRNA,

MIR6505 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR6505 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6505 Gene

No ASD Table

Relevant External Links for MIR6505 Gene

GeneLoc Exon Structure for
MIR6505

Expression for MIR6505 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6505 Gene

Orthologs for MIR6505 Gene

Evolution for MIR6505 Gene

ENSEMBL:
Gene Tree for MIR6505 (if available)
TreeFam:
Gene Tree for MIR6505 (if available)

No data available for Orthologs for MIR6505 Gene

Paralogs for MIR6505 Gene

No data available for Paralogs for MIR6505 Gene

Variants for MIR6505 Gene

Additional dbSNP identifiers (rs#s) for MIR6505 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6505 Gene

Variant ID Type Subtype PubMed ID
esv2759898 CNV gain+loss 17122850
nsv508673 CNV deletion 20534489

Additional Variant Information for MIR6505 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6505

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6505 Gene

Disorders for MIR6505 Gene

Additional Disease Information for MIR6505

No disorders were found for MIR6505 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6505 Gene

Publications for MIR6505 Gene

  1. ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas. (PMID: 30232004) Abraham CG … Espinosa JM (Cell reports 2018) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6505 Gene

Sources for MIR6505 Gene