microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6504 Gene

Data sources for MIR6504 Gene:

Subcategory (RNA class) for MIR6504 Gene

miRNA

Aliases for MIR6504 Gene

External Ids for MIR6504 Gene

Previous GeneCards Identifiers for MIR6504 Gene

  • GC16U901744

Summaries for MIR6504 Gene

Entrez Gene Summary for MIR6504 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6504 Gene

MIR6504 (MicroRNA 6504) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6504 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6504 Gene

Genomics for MIR6504 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6504 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J081608 Promoter/Enhancer 1.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 250.7 -0.4 -417 5.7 RBM22 JUND SPI1 MAFK REST ZBTB33 ZNF664 NR2F1 RAD21 ATF2 MIR6504 CMIP MIR7854 PLCG2
GH16J081613 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +5.0 5027 3.9 PLRG1 FOXA1 FOXA2 SP1 NBN NONO ZNF148 EBF1 CTBP1 ZNF843 ENSG00000279681 HSALNG0112998 CMIP MIR6504 PLCG2
GH16J081598 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -10.6 -10558 4.8 FEZF1 CTCF ZIC2 SAP130 RXRA PRDM1 SIN3A TEAD3 JUND PRDM6 CMC2 ENSG00000260495 GAN MIR6504 MIR7854 PLCG2 CMIP
GH16J081591 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -18.9 -18851 2.6 CHD2 CEBPA KDM6A THAP11 SMAD4 SAP130 ETV4 GABPB1 RARA TEAD3 CMIP CMC2 MIR6504 MIR7854 PLCG2
GH16J081597 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -15.3 -15347 4 CEBPA THAP11 CEBPB FOXA2 SMAD4 SAP130 RXRA MIER3 ZSCAN9 RARA MIR6504 MIR7854 PLCG2 CMIP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6504 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6504 Gene

Latest Assembly
chr16:81,611,348-81,611,408
(GRCh38/hg38)
Size:
61 bases
Orientation:
Plus strand

Previous Assembly
chr16:81,644,953-81,645,013
(GRCh37/hg19 by Entrez Gene)
Size:
61 bases
Orientation:
Plus strand

Genomic View for MIR6504 Gene

Genes around MIR6504 on UCSC Golden Path with GeneCards custom track
MIR6504 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6504 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6504 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6504 Gene

Proteins for MIR6504 Gene

Post-translational modifications for MIR6504 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6504 Gene

Domains & Families for MIR6504 Gene

Gene Families for MIR6504 Gene

HGNC:
genes like me logo Genes that share domains with MIR6504: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6504 Gene

Function for MIR6504 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6504 Gene

Localization for MIR6504 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6504 Gene

Pathways & Interactions for MIR6504 Gene

PathCards logo

SuperPathways for MIR6504 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6504 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6504 Gene

Drugs & Compounds for MIR6504 Gene

No Compound Related Data Available

Transcripts for MIR6504 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6504 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C26E_9606 precursor_RNA 61 3

RefSeq: NR_106759,

Ensembl: ENST00000613520 (view in UCSC) ,

miRBase: MI0022216,

URS000075B71A_9606 miRNA 21 2

RefSeq: NR_106759,

miRBase: MIMAT0025464,

URS000075C041_9606 miRNA 20 2

RefSeq: NR_106759,

miRBase: MIMAT0025465,

MIR6504 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6504 Gene

No ASD Table

Relevant External Links for MIR6504 Gene

GeneLoc Exon Structure for
MIR6504

No data available for mRNA/cDNA for MIR6504 Gene

Expression for MIR6504 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6504 Gene

Orthologs for MIR6504 Gene

Evolution for MIR6504 Gene

ENSEMBL:
Gene Tree for MIR6504 (if available)
TreeFam:
Gene Tree for MIR6504 (if available)

No data available for Orthologs for MIR6504 Gene

Paralogs for MIR6504 Gene

No data available for Paralogs for MIR6504 Gene

Variants for MIR6504 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6504 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6504 Gene

Variant ID Type Subtype PubMed ID
esv3639335 CNV loss 21293372

Additional Variant Information for MIR6504 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6504

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6504 Gene

Disorders for MIR6504 Gene

Additional Disease Information for MIR6504

No disorders were found for MIR6504 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6504 Gene

Publications for MIR6504 Gene

  1. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6504 Gene

Sources for MIR6504 Gene