microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6502 Gene

Subcategory (RNA class) for MIR6502 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR6502 Gene

  • MicroRNA 6502 2 3 5
  • MicroRNA Mir-6502 3
  • Hsa-Mir-6502 3
  • MIMAT0025460 51
  • MIMAT0025461 51
  • MI0022214 51
  • MIR6502 2

External Ids for MIR6502 Gene

Previous GeneCards Identifiers for MIR6502 Gene

  • GC12U901913
  • GC12P066254
  • GC12P066256
  • GC12P066257
  • GC12P066258
  • GC12P066189

Summaries for MIR6502 Gene

Entrez Gene Summary for MIR6502 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6502 Gene

MIR6502 (MicroRNA 6502) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Toll-like Receptor Signaling Pathway and Activated TLR4 signalling.

Additional gene information for MIR6502 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6502 Gene

Genomics for MIR6502 Gene

GeneHancer (GH) Regulatory Elements for MIR6502 Gene

Promoters and enhancers for MIR6502 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J066249 Enhancer 0.2 dbSUPER 500.7 -0.4 -378 2.1 MIR6502 lnc-HELB-2 HELB RBMS1P1 IRAK3
GH12J066234 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -15.7 -15681 2 CTCF ZNF10 ZBTB26 CTBP1 POLR2A OSR2 SIN3A SP2 CREB3L1 ZNF263 RBMS1P1 IRAK3 TMBIM4 ENSG00000228144 HELB ENSG00000256072 LLPH LLPH-DT MIR6502
GH12J066240 Promoter/Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -9.3 -9256 0.9 FOS GABPA MAFK RXRA CEBPB SP1 PRDM1 ATF3 STAT3 IRAK3 HELB MIR6502 RBMS1P1
GH12J066247 Enhancer 0.4 Ensembl dbSUPER 0.7 -3.3 -3281 0.8 SPI1 HELB MIR6502 RBMS1P1 IRAK3
GH12J066236 Promoter/Enhancer 0.6 Ensembl dbSUPER 0.4 -14.4 -14381 0.2 ZNF362 RBMS1P1 IRAK3 MIR6502
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6502 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6502 Gene

Genomic Locations for MIR6502 Gene
chr12:66,251,082-66,251,157
(GRCh38/hg38)
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR6502 Gene

Genes around MIR6502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6502 Gene

Proteins for MIR6502 Gene

Post-translational modifications for MIR6502 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6502 Gene

Domains & Families for MIR6502 Gene

Gene Families for MIR6502 Gene

HGNC:
genes like me logo Genes that share domains with MIR6502: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6502 Gene

Function for MIR6502 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6502 Gene

Localization for MIR6502 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6502 Gene

Pathways & Interactions for MIR6502 Gene

genes like me logo Genes that share pathways with MIR6502: view
;

Gene Ontology (GO) - Biological Process for MIR6502 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6502 Gene

Drugs & Compounds for MIR6502 Gene

No Compound Related Data Available

Transcripts for MIR6502 Gene

mRNA/cDNA for MIR6502 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6502 Gene

No ASD Table

Relevant External Links for MIR6502 Gene

GeneLoc Exon Structure for
MIR6502

Expression for MIR6502 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6502 Gene

Orthologs for MIR6502 Gene

Evolution for MIR6502 Gene

ENSEMBL:
Gene Tree for MIR6502 (if available)
TreeFam:
Gene Tree for MIR6502 (if available)

No data available for Orthologs for MIR6502 Gene

Paralogs for MIR6502 Gene

No data available for Paralogs for MIR6502 Gene

Variants for MIR6502 Gene

Additional dbSNP identifiers (rs#s) for MIR6502 Gene

Additional Variant Information for MIR6502 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6502 Gene

Disorders for MIR6502 Gene

Additional Disease Information for MIR6502

No disorders were found for MIR6502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6502 Gene

Publications for MIR6502 Gene

  1. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6502 Gene

Sources for MIR6502 Gene