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Aliases for MIR630 Gene

Subcategory (RNA class) for MIR630 Gene


Quality Score for this RNA gene is


Aliases for MIR630 Gene

  • MicroRNA 630 2 3 5
  • Hsa-Mir-630 3
  • MIRN630 3

External Ids for MIR630 Gene

ORGUL Members for MIR630 Gene

Previous HGNC Symbols for MIR630 Gene

  • MIRN630

Previous GeneCards Identifiers for MIR630 Gene

  • GC15P070667
  • GC15P072879
  • GC15P072475

Summaries for MIR630 Gene

Entrez Gene Summary for MIR630 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR630 Gene

MIR630 (MicroRNA 630) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR630 include Bladder Urothelial Carcinoma. Among its related pathways are Cytokine Signaling in Immune system and Transport of the SLBP independent Mature mRNA.

Additional gene information for MIR630 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR630 Gene

Genomics for MIR630 Gene

GeneHancer (GH) Regulatory Elements for MIR630 Gene

Promoters and enhancers for MIR630 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I072554 Enhancer 0.6 ENCODE 11.2 -32.0 -32000 2.2 ZSCAN5A SOX13 KLF17 ZNF2 ZNF121 SCRT2 ZNF350 ZNF600 FOS ZNF18 HEXA MIR630 ENSG00000261187 RPL12P35 ENSG00000260534 GC15P072588 GC15P072506 ARIH1
GH15I072616 Enhancer 0.4 ENCODE 11.4 +28.8 28808 0.2 MITF CTCF KDM1A ENSG00000260672 MIR630 GOLGA6B LINC02259
GH15I072615 Enhancer 0.2 ENCODE 11.4 +28.4 28360 0.5 ENSG00000260672 MIR630 GC15P072623 GOLGA6B LINC02259
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR630 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR630 Gene

Genomic Locations for MIR630 Gene
97 bases
Plus strand

Genomic View for MIR630 Gene

Genes around MIR630 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR630 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR630 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR630 Gene

Proteins for MIR630 Gene

Post-translational modifications for MIR630 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR630 Gene

Domains & Families for MIR630 Gene

Gene Families for MIR630 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR630: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR630 Gene

Function for MIR630 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR630 Gene

Localization for MIR630 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR630 Gene

Pathways & Interactions for MIR630 Gene

genes like me logo Genes that share pathways with MIR630: view

Interacting Proteins for MIR630 Gene

Gene Ontology (GO) - Biological Process for MIR630 Gene


No data available for SIGNOR curated interactions for MIR630 Gene

Drugs & Compounds for MIR630 Gene

No Compound Related Data Available

Transcripts for MIR630 Gene

mRNA/cDNA for MIR630 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR630 Gene

No ASD Table

Relevant External Links for MIR630 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR630 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR630 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR630 Gene:

genes like me logo Genes that share expression patterns with MIR630: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR630 Gene

Orthologs for MIR630 Gene

Evolution for MIR630 Gene

Gene Tree for MIR630 (if available)
Gene Tree for MIR630 (if available)

No data available for Orthologs for MIR630 Gene

Paralogs for MIR630 Gene

No data available for Paralogs for MIR630 Gene

Variants for MIR630 Gene

Sequence variations from dbSNP and Humsavar for MIR630 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000923680 -- 72,586,869(+) T/G upstream_transcript_variant
rs1001875411 -- 72,587,343(+) A/G downstream_transcript_variant
rs1002355543 -- 72,586,021(+) C/T upstream_transcript_variant
rs1002940661 -- 72,586,265(+) C/G upstream_transcript_variant
rs1003877392 -- 72,586,320(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR630 Gene

Variant ID Type Subtype PubMed ID
nsv483057 CNV loss 15286789
nsv428307 CNV gain 18775914
esv2760039 CNV gain+loss 17122850

Additional Variant Information for MIR630 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR630 Gene

Disorders for MIR630 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR630 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
bladder urothelial carcinoma
  • bladder transitional cell carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR630

genes like me logo Genes that share disorders with MIR630: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR630 Gene

Publications for MIR630 Gene

  1. MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells. (PMID: 28601080) Feng J … Feng C (Biochemistry. Biokhimiia 2017) 3 58
  2. Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (PMID: 26725326) Rupaimoole R … Sood AK (Oncogene 2016) 3 58
  3. MicroRNA-630 suppresses tumor metastasis through the TGF-β- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma. (PMID: 26993767) Chen WX … Chen XP (Oncotarget 2016) 3 58
  4. Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea. (PMID: 27163713) Khalyfa A … Gozal D (American journal of respiratory and critical care medicine 2016) 3 58
  5. Expression of miRNA-630 in bladder urothelial carcinoma and its clinical significance. (PMID: 27752905) Wang ZY … Wei JX (Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016) 3 58

Products for MIR630 Gene

Sources for MIR630 Gene

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