Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR628 Gene

Subcategory (RNA class) for MIR628 Gene


Quality Score for this RNA gene is


Aliases for MIR628 Gene

  • MicroRNA 628 2 3 5
  • Hsa-Mir-628 3
  • Mir-628 3
  • MIRN628 3

External Ids for MIR628 Gene

Previous HGNC Symbols for MIR628 Gene

  • MIRN628

Previous GeneCards Identifiers for MIR628 Gene

  • GC15M053453
  • GC15M055665
  • GC15M055480
  • GC15M055481

Summaries for MIR628 Gene

Entrez Gene Summary for MIR628 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR628 Gene

MIR628 (MicroRNA 628) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR628 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR628

Additional gene information for MIR628 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR628 Gene

Genomics for MIR628 Gene

GeneHancer (GH) Regulatory Elements for MIR628 Gene

Promoters and enhancers for MIR628 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I055396 Enhancer 0.9 ENCODE 13.1 -24.1 -24074 0.9 HDAC1 ARNT NFRKB CHAMP1 GTF3C2 TCF12 GATA2 EGR1 ATF7 ZBTB2 GC15M057427 MIR628 C15orf65 PIGB DNAAF4 CCPG1 DNAAF4-CCPG1
GH15I055394 Enhancer 0.5 ENCODE 11.5 -21.8 -21844 0.2 PRDM6 POLR2A CEBPB TRIM24 ZNF843 MIR628 C15orf65 DNAAF4 GC15M057427 CCPG1 DNAAF4-CCPG1
GH15I055395 Enhancer 0.4 Ensembl 11.5 -22.1 -22066 0.2 POLR2A CEBPB TRIM24 MIR628 GC15M057427 CCPG1 DNAAF4-CCPG1
GH15I055344 Enhancer 0.3 ENCODE 12 +28.6 28596 0.2 GATA3 ENSG00000274765 MIR628 ENSG00000277548 PIGB CCPG1
GH15I055391 Promoter 0.5 EPDnew 0.4 -18.9 -18886 0.1 CCPG1 GC15M057427 MIR628 DNAAF4-CCPG1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR628 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR628 Gene

Genomic Locations for MIR628 Gene
95 bases
Minus strand

Genomic View for MIR628 Gene

Genes around MIR628 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR628 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR628 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR628 Gene

ORGUL Member Location for MIR628 Gene

ORGUL Member Location for MIR628 gene

Proteins for MIR628 Gene

Post-translational modifications for MIR628 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR628 Gene

Domains & Families for MIR628 Gene

Gene Families for MIR628 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR628: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR628 Gene

Function for MIR628 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR628 Gene

Localization for MIR628 Gene

Gene Ontology (GO) - Cellular Components for MIR628 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR628: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR628 Gene

Pathways & Interactions for MIR628 Gene

SuperPathways for MIR628 Gene

No Data Available

Interacting Proteins for MIR628 Gene

Gene Ontology (GO) - Biological Process for MIR628 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR628 Gene

Drugs & Compounds for MIR628 Gene

No Compound Related Data Available

Transcripts for MIR628 Gene

fRNAdb Secondary structures for MIR628 Gene

  • hsa-miR-628-3p_MIMAT0003297_Homo_sapiens_miR-628-3p_mature

mRNA/cDNA for MIR628 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR628 Gene

No ASD Table

Relevant External Links for MIR628 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR628 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR628 Gene

mRNA differential expression in normal tissues according to GTEx for MIR628 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x9.1), Brain - Cerebellum (x7.3), Brain - Cortex (x6.4), Brain - Nucleus accumbens (basal ganglia) (x5.3), and Brain - Anterior cingulate cortex (BA24) (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of MIR628 Gene:

genes like me logo Genes that share expression patterns with MIR628: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR628 Gene

Orthologs for MIR628 Gene

Evolution for MIR628 Gene

Gene Tree for MIR628 (if available)
Gene Tree for MIR628 (if available)

No data available for Orthologs for MIR628 Gene

Paralogs for MIR628 Gene

No data available for Paralogs for MIR628 Gene

Variants for MIR628 Gene

Sequence variations from dbSNP and Humsavar for MIR628 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1001572133 -- 55,374,654(-) G/A upstream_transcript_variant
rs1003005959 -- 55,373,670(-) A/G upstream_transcript_variant
rs1003338158 -- 55,374,818(-) A/T upstream_transcript_variant
rs1004449910 -- 55,372,760(-) T/G downstream_transcript_variant
rs1004783308 -- 55,374,309(-) AAAAAAAA/AAAAAAAAA upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR628 Gene

Variant ID Type Subtype PubMed ID
esv2761899 CNV gain+loss 21179565
esv3569598 CNV gain 25503493
nsv1043789 CNV gain 25217958
nsv520799 CNV loss 19592680
nsv569523 CNV gain 21841781

Additional Variant Information for MIR628 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR628 Gene

Disorders for MIR628 Gene

Additional Disease Information for MIR628

No disorders were found for MIR628 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR628 Gene

Publications for MIR628 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. MicroRNA 628-5p as a Novel Biomarker for Cardiac Allograft Vasculopathy. (PMID: 27653298) Neumann A … Bara C (Transplantation 2017) 3 58
  3. miR-628-3p regulates osteoblast differentiation by targeting RUNX2: Possible role in atrophic non-union. (PMID: 28035362) Chen H … Tang P (International journal of molecular medicine 2017) 3 58
  4. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  5. Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma. (PMID: 27057628) Jasinski-Bergner S … Seliger B (Oncotarget 2016) 3 58

Products for MIR628 Gene

Sources for MIR628 Gene

Loading form....