Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR624 Gene

Subcategory (RNA class) for MIR624 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR624 Gene

  • MicroRNA 624 2 3 5
  • Hsa-Mir-624 3
  • Mir-624 3
  • MIRN624 3

External Ids for MIR624 Gene

Previous HGNC Symbols for MIR624 Gene

  • MIRN624

Previous GeneCards Identifiers for MIR624 Gene

  • GC14M030554
  • GC14M031483

Summaries for MIR624 Gene

Entrez Gene Summary for MIR624 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR624 Gene

MIR624 (MicroRNA 624) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR624 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

Additional gene information for MIR624 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR624 Gene

Genomics for MIR624 Gene

GeneHancer (GH) Regulatory Elements for MIR624 Gene

Promoters and enhancers for MIR624 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I031037 Enhancer 1.2 Ensembl ENCODE 12.3 -23.8 -23792 2.1 FOXA2 ARNT ARID4B DMAP1 YY1 SLC30A9 TCF12 ATF7 FOS RXRA MIR624 G2E3 HEATR5A AP4S1 STRN3 RPL21P5
GH14I031056 Enhancer 1.2 Ensembl ENCODE 12.3 -44.4 -44416 4.7 PKNOX1 SMAD1 ARNT YY1 ZNF766 MCM3 REST ZNF592 KAT8 MEF2D STRN3 AP4S1 MIR624 HEATR5A RPL21P5
GH14I030980 Enhancer 1 Ensembl ENCODE 12.3 +34.3 34341 0.8 ARID4B SIN3A ZNF48 RAD21 RFX5 ARID2 EGR1 ZNF143 THAP11 MIXL1 MIR624 AP4S1 RNU6-541P STRN3 HIGD1AP17
GH14I031082 Enhancer 0.8 ENCODE 12.4 -67.4 -67448 0.2 ELF3 FOXA2 MLX ARID4B IRF4 THRB RAD21 RARA SLC30A9 ZNF143 AP4S1 MIR624 RPL21P5 STRN3
GH14I030972 Enhancer 0.8 Ensembl ENCODE 11.7 +42.5 42454 0.2 PKNOX1 GATAD2B DPF2 ZNF217 GATA3 CTBP1 CUX1 FOS MIR624 AP4S1 HIGD1AP17 STRN3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR624 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR624 Gene

Genomic Locations for MIR624 Gene
chr14:31,014,646-31,014,742
(GRCh38/hg38)
Size:
97 bases
Orientation:
Minus strand
chr14:31,483,852-31,483,948
(GRCh37/hg19)

Genomic View for MIR624 Gene

Genes around MIR624 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR624 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR624 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR624 Gene

ORGUL Member Location for MIR624 Gene

ORGUL Member Location for MIR624 gene

Proteins for MIR624 Gene

Post-translational modifications for MIR624 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR624 Gene

Domains & Families for MIR624 Gene

Gene Families for MIR624 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR624: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR624 Gene

Function for MIR624 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR624 Gene

Localization for MIR624 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR624 Gene

Pathways & Interactions for MIR624 Gene

SuperPathways for MIR624 Gene

No Data Available

Interacting Proteins for MIR624 Gene

Gene Ontology (GO) - Biological Process for MIR624 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR624 Gene

Drugs & Compounds for MIR624 Gene

No Compound Related Data Available

Transcripts for MIR624 Gene

mRNA/cDNA for MIR624 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR624 Gene

No ASD Table

Relevant External Links for MIR624 Gene

GeneLoc Exon Structure for
MIR624
ECgene alternative splicing isoforms for
MIR624

Expression for MIR624 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR624 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR624 Gene:

MIR624
genes like me logo Genes that share expression patterns with MIR624: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR624 Gene

Orthologs for MIR624 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR624 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-624 34
  • 100 (a)
OneToOne
Species where no ortholog for MIR624 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR624 Gene

ENSEMBL:
Gene Tree for MIR624 (if available)
TreeFam:
Gene Tree for MIR624 (if available)

Paralogs for MIR624 Gene

No data available for Paralogs for MIR624 Gene

Variants for MIR624 Gene

Sequence variations from dbSNP and Humsavar for MIR624 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000769401 -- 31,015,009(-) T/C upstream_transcript_variant
rs1001039140 -- 31,016,542(-) A/T upstream_transcript_variant
rs1002533874 -- 31,016,685(-) C/T upstream_transcript_variant
rs1002735478 -- 31,014,966(-) T/G upstream_transcript_variant
rs1004473683 -- 31,015,526(-) C/ upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR624 Gene

Variant ID Type Subtype PubMed ID
esv33189 CNV loss 17666407
esv3892495 CNV gain 25118596
nsv1049063 CNV gain 25217958
nsv564169 CNV gain 21841781

Additional Variant Information for MIR624 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR624

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR624 Gene

Disorders for MIR624 Gene

Additional Disease Information for MIR624

No disorders were found for MIR624 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR624 Gene

Publications for MIR624 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Platelets in patients with premature coronary artery disease exhibit upregulation of miRNA340* and miRNA624*. (PMID: 22022480) Sondermeijer BM … Pinto-Sietsma SJ (PloS one 2011) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR624 Gene

Sources for MIR624 Gene

Content
Loading form....