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Aliases for MIR622 Gene

Subcategory (RNA class) for MIR622 Gene


Quality Score for this RNA gene is


Aliases for MIR622 Gene

  • MicroRNA 622 2 3 5
  • Hsa-Mir-622 3
  • MIRN622 3

External Ids for MIR622 Gene

ORGUL Members for MIR622 Gene

Previous HGNC Symbols for MIR622 Gene

  • MIRN622

Previous GeneCards Identifiers for MIR622 Gene

  • GC13P089683
  • GC13P090886
  • GC13P090888
  • GC13P090891
  • GC13P090894
  • GC13P090897
  • GC13P090900
  • GC13P090903
  • GC13P090906
  • GC13P090911
  • GC13P090916
  • GC13P090920

Summaries for MIR622 Gene

Entrez Gene Summary for MIR622 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR622 Gene

MIR622 (MicroRNA 622) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR622 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR622 Gene

Genomics for MIR622 Gene

Genomic Locations for MIR622 Gene

Genomic Locations for MIR622 Gene
96 bases
Plus strand

Genomic View for MIR622 Gene

Genes around MIR622 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR622 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR622 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR622 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR622 Gene

Proteins for MIR622 Gene

Post-translational modifications for MIR622 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR622 Gene

Domains & Families for MIR622 Gene

Gene Families for MIR622 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR622: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR622 Gene

Function for MIR622 Gene

Phenotypes From GWAS Catalog for MIR622 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR622 Gene

Localization for MIR622 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR622 Gene

Pathways & Interactions for MIR622 Gene

SuperPathways for MIR622 Gene

No Data Available

Interacting Proteins for MIR622 Gene

Gene Ontology (GO) - Biological Process for MIR622 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR622 Gene

Drugs & Compounds for MIR622 Gene

No Compound Related Data Available

Transcripts for MIR622 Gene

mRNA/cDNA for MIR622 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR622 Gene

No ASD Table

Relevant External Links for MIR622 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR622 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR622 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR622 Gene:

genes like me logo Genes that share expression patterns with MIR622: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR622 Gene

Orthologs for MIR622 Gene

Evolution for MIR622 Gene

Gene Tree for MIR622 (if available)
Gene Tree for MIR622 (if available)

No data available for Orthologs for MIR622 Gene

Paralogs for MIR622 Gene

No data available for Paralogs for MIR622 Gene

Variants for MIR622 Gene

Sequence variations from dbSNP and Humsavar for MIR622 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000565739 -- 90,231,504(+) A/C downstream_transcript_variant
rs1000730448 -- 90,231,653(+) A/G downstream_transcript_variant
rs1002969725 -- 90,230,410(+) C/T upstream_transcript_variant
rs1003103500 -- 90,230,205(+) C/A upstream_transcript_variant
rs1003902304 -- 90,229,233(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR622 Gene

Variant ID Type Subtype PubMed ID
dgv1728n100 CNV loss 25217958
nsv1038041 CNV gain 25217958
nsv1039817 CNV loss 25217958
nsv456064 CNV loss 19166990
nsv562644 CNV loss 21841781
nsv983611 CNV duplication 23825009

Additional Variant Information for MIR622 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR622 Gene

Disorders for MIR622 Gene

Additional Disease Information for MIR622

No disorders were found for MIR622 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR622 Gene

Publications for MIR622 Gene

  1. MiR-622 functions as a tumor suppressor and directly targets E2F1 in human esophageal squamous cell carcinoma. (PMID: 27501502) Song C … Wang Z (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58
  2. Upregulated miRNA-622 inhibited cell proliferation, motility, and invasion via repressing Kirsten rat sarcoma in glioblastoma. (PMID: 26596833) Wang X … Ma J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 58
  3. MiR-622 inhibited colorectal cancer occurrence and metastasis by suppressing K-Ras. (PMID: 26333174) Fang Y … Xiang J (Molecular carcinogenesis 2016) 3 58
  4. Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer. (PMID: 26528854) Cheng CW … Shen CY (Oncotarget 2015) 3 58
  5. microRNA-622 acts as a tumor suppressor in hepatocellular carcinoma. (PMID: 26467022) Song WH … Xu AM (Cancer biology & therapy 2015) 3 58

Products for MIR622 Gene

Sources for MIR622 Gene

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