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Aliases for MIR620 Gene

Subcategory (RNA class) for MIR620 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR620 Gene

  • MicroRNA 620 2 3 5
  • Hsa-Mir-620 3
  • MIRN620 3

External Ids for MIR620 Gene

Previous HGNC Symbols for MIR620 Gene

  • MIRN620

Previous GeneCards Identifiers for MIR620 Gene

  • GC12U901028
  • GC12M115072
  • GC12M116586

Summaries for MIR620 Gene

Entrez Gene Summary for MIR620 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR620 Gene

MIR620 (MicroRNA 620) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR620 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR620

Additional gene information for MIR620 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR620 Gene

Genomics for MIR620 Gene

GeneHancer (GH) Regulatory Elements for MIR620 Gene

Promoters and enhancers for MIR620 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I116148 Enhancer 0.6 Ensembl ENCODE 550.8 -0.6 -648 0.8 PRDM6 JUN RUNX3 MIR620 SNRPGP18 MED13L
GH12I116149 Enhancer 0.6 dbSUPER 550.8 -1.8 -1823 1.5 PKNOX1 PRDM6 GATA3 NFIC JUND POLR2A KDM1A RCOR1 CHD2 MIR620 SNRPGP18 MED13L
GH12I116121 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +25.8 25806 3.5 PKNOX1 ARNT SIN3A FEZF1 ZNF2 IRF4 ATF7 RUNX3 ZNF214 ZNF202 FBXW8 MAP1LC3B2 MED13L MIR620 ENSG00000258034 GC12M116089 GC12P116137
GH12I116171 Enhancer 1.1 Ensembl ENCODE dbSUPER 12 -23.6 -23611 1.5 HDAC1 MEIS2 IRF2 ATF1 PKNOX1 TEAD4 JUN CTBP1 FOSL2 NFE2 MIR620 MED13L SNRPGP18 ENSG00000258337
GH12I116203 Enhancer 0.7 ENCODE dbSUPER 12 -54.5 -54488 0.1 CTCF PRDM6 TEAD4 GFI1B KDM1A MIR620 PIR52842 ENSG00000258337 MED13L
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR620 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR620 Gene

Genomic Locations for MIR620 Gene
chr12:116,148,560-116,148,654
(GRCh38/hg38)
Size:
95 bases
Orientation:
Minus strand
chr12:116,586,365-116,586,459
(GRCh37/hg19)

Genomic View for MIR620 Gene

Genes around MIR620 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR620 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR620 Gene

ORGUL Member Location for MIR620 Gene

ORGUL Member Location for MIR620 gene

Proteins for MIR620 Gene

Post-translational modifications for MIR620 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR620 Gene

Domains & Families for MIR620 Gene

Gene Families for MIR620 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR620: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR620 Gene

Function for MIR620 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR620 Gene

Localization for MIR620 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR620 Gene

Pathways & Interactions for MIR620 Gene

SuperPathways for MIR620 Gene

No Data Available

Interacting Proteins for MIR620 Gene

Gene Ontology (GO) - Biological Process for MIR620 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR620 Gene

Drugs & Compounds for MIR620 Gene

No Compound Related Data Available

Transcripts for MIR620 Gene

fRNAdb Secondary structures for MIR620 Gene

  • FR238828

mRNA/cDNA for MIR620 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR620 Gene

No ASD Table

Relevant External Links for MIR620 Gene

GeneLoc Exon Structure for
MIR620
ECgene alternative splicing isoforms for
MIR620

Expression for MIR620 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR620 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR620 Gene:

MIR620
genes like me logo Genes that share expression patterns with MIR620: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR620 Gene

Orthologs for MIR620 Gene

Evolution for MIR620 Gene

ENSEMBL:
Gene Tree for MIR620 (if available)
TreeFam:
Gene Tree for MIR620 (if available)

No data available for Orthologs for MIR620 Gene

Paralogs for MIR620 Gene

No data available for Paralogs for MIR620 Gene

Variants for MIR620 Gene

Sequence variations from dbSNP and Humsavar for MIR620 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1002942589 -- 116,148,129(-) T/C downstream_transcript_variant
rs1003719367 -- 116,149,806(-) T/C upstream_transcript_variant
rs1005059505 -- 116,148,262(-) G/A downstream_transcript_variant
rs1005379971 -- 116,150,020(-) G/A upstream_transcript_variant
rs1005459625 -- 116,148,607(-) A/G non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR620 Gene

Variant ID Type Subtype PubMed ID
nsv832522 CNV loss 17160897
nsv952488 CNV duplication 24416366

Additional Variant Information for MIR620 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR620

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR620 Gene

Disorders for MIR620 Gene

Additional Disease Information for MIR620

No disorders were found for MIR620 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR620 Gene

Publications for MIR620 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. GPC5, a tumor suppressor, is regulated by miR-620 in lung adenocarcinoma. (PMID: 24682381) Zhao Z … Cheng L (Molecular medicine reports 2014) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR620 Gene

Sources for MIR620 Gene

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