microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6165 Gene

Data sources for MIR6165 Gene:

RNA type for MIR6165 Gene

miRNA

Aliases for MIR6165 Gene

External Ids for MIR6165 Gene

Previous GeneCards Identifiers for MIR6165 Gene

  • GC17U902000

Summaries for MIR6165 Gene

Entrez Gene Summary for MIR6165 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6165 Gene

MIR6165 (MicroRNA 6165) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6165 include Noonan Syndrome 5 and Moyamoya Disease 1.

Additional gene information for MIR6165 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6165 Gene

Genomics for MIR6165 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6165 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6165 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6165 Gene

Latest Assembly
chr17:49,510,817-49,510,900
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand

Previous Assembly
chr17:47,588,179-47,588,262
(GRCh37/hg19 by Entrez Gene)
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR6165 Gene

Genes around MIR6165 on UCSC Golden Path with GeneCards custom track
MIR6165 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6165 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6165 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6165 Gene

Proteins for MIR6165 Gene

Post-translational modifications for MIR6165 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6165 Gene

Domains & Families for MIR6165 Gene

Gene Families for MIR6165 Gene

HGNC:
genes like me logo Genes that share domains with MIR6165: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6165 Gene

Function for MIR6165 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6165 Gene

Localization for MIR6165 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6165 Gene

Pathways & Interactions for MIR6165 Gene

PathCards logo

SuperPathways for MIR6165 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6165 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6165 Gene

Drugs & Compounds for MIR6165 Gene

No Compound Related Data Available

Transcripts for MIR6165 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6165 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075BB89_9606 precursor_RNA 84 3

RefSeq: NR_106751,

Ensembl: ENST00000614803 (view in UCSC) ,

miRBase: MI0021472,

URS0000298172_9606 miRNA 19 3

RefSeq: NR_106751,

miRBase: MIMAT0024782,

ENA: FR873488.1:1..19:ncRNA,

URS000057EA55_9606 miRNA 26 1

ENA: FR863632.1:1..26:ncRNA,

URS00001B7DE9_9606 miRNA 23 1

ENA: FR873489.1:1..23:ncRNA,

MIR6165 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6165 Gene

No ASD Table

Relevant External Links for MIR6165 Gene

GeneLoc Exon Structure for
MIR6165

No data available for mRNA/cDNA for MIR6165 Gene

Expression for MIR6165 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6165 Gene

Orthologs for MIR6165 Gene

Evolution for MIR6165 Gene

ENSEMBL:
Gene Tree for MIR6165 (if available)
TreeFam:
Gene Tree for MIR6165 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR6165

No data available for Orthologs for MIR6165 Gene

Paralogs for MIR6165 Gene

No data available for Paralogs for MIR6165 Gene

Variants for MIR6165 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6165 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6165 Gene

Variant ID Type Subtype PubMed ID
nsv833473 CNV gain+loss 17160897

Additional Variant Information for MIR6165 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6165
Leiden Open Variation Database (LOVD)
MIR6165

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6165 Gene

Disorders for MIR6165 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR6165 Gene - From: COP

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6165

genes like me logo Genes that share disorders with MIR6165: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6165 Gene

Publications for MIR6165 Gene

  1. Expression and Function of hsa-miR-6165 in Human Cell Lines and During the NT2 Cell Neural Differentiation Process. (PMID: 28956260) Hassanlou M … Mowla SJ (Journal of molecular neuroscience : MN 2017) 3
  2. Experimental verification of a predicted intronic microRNA in human NGFR gene with a potential pro-apoptotic function. (PMID: 22558167) Parsi S … Mowla SJ (PloS one 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6165 Gene

Sources for MIR6165 Gene