microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6129 Gene

Data sources for MIR6129 Gene:

RNA type for MIR6129 Gene

miRNA

Aliases for MIR6129 Gene

External Ids for MIR6129 Gene

Previous GeneCards Identifiers for MIR6129 Gene

  • GC17U902078

Summaries for MIR6129 Gene

Entrez Gene Summary for MIR6129 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6129 Gene

MIR6129 (MicroRNA 6129) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6129 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6129 Gene

Genomics for MIR6129 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6129 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J049278 Enhancer 0.6 Ensembl 0.4 +10.5 10453 0.8 CEBPA CEBPB PRDM1 RARA TBX3 BHLHE40 NR2F6 CEBPG NFIL3 NR2F1 HSALNG0117169 FLJ40194 ZNF652 MIR6129 PHOSPHO1
GH17J049276 Enhancer 0.4 ENCODE 0.4 +11.6 11600 0.2 CTCF RAD21 SMC3 POU5F1 HSALNG0117169 PHOSPHO1 MIR6129 FLJ40194 ZNF652
GH17J049277 Enhancer 0.4 Ensembl 0.4 +11.4 11353 0.2 RAD21 SMC3 CTCF POU5F1 HSALNG0117169 MIR6129 PHOSPHO1 FLJ40194 ZNF652
GH17J049280 Enhancer 0.3 Ensembl 0.4 +7.3 7253 0.8 NR2F6 NR2F1 ZNF652 MIR6129 HSALNG0117169 PHOSPHO1 FLJ40194
GH17J049285 Enhancer 0.2 Ensembl 0.7 +2.6 2553 0.2 RPL21P124 ENSG00000250186 PHB GNGT2 ABI3 FLJ40194 MIR6129 HSALNG0117169 PHOSPHO1 ZNF652
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6129 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6129 Gene

Latest Assembly
chr17:49,288,346-49,288,454
(GRCh38/hg38)
Size:
109 bases
Orientation:
Minus strand

Previous Assembly
chr17:47,365,708-47,365,816
(GRCh37/hg19 by Entrez Gene)
Size:
109 bases
Orientation:
Minus strand

Genomic View for MIR6129 Gene

Genes around MIR6129 on UCSC Golden Path with GeneCards custom track
MIR6129 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6129 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6129 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6129 Gene

Proteins for MIR6129 Gene

Post-translational modifications for MIR6129 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6129 Gene

Domains & Families for MIR6129 Gene

Gene Families for MIR6129 Gene

HGNC:
genes like me logo Genes that share domains with MIR6129: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6129 Gene

Function for MIR6129 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6129 Gene

Localization for MIR6129 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6129 Gene

Pathways & Interactions for MIR6129 Gene

PathCards logo

SuperPathways for MIR6129 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6129 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6129 Gene

Drugs & Compounds for MIR6129 Gene

No Compound Related Data Available

Transcripts for MIR6129 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6129 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075D3F4_9606 precursor_RNA 109 3

RefSeq: NR_106745,

Ensembl: ENST00000616087 (view in UCSC) ,

miRBase: MI0021274,

URS000075DA70_9606 miRNA 19 2

RefSeq: NR_106745,

miRBase: MIMAT0024613,

MIR6129 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6129 Gene

No ASD Table

Relevant External Links for MIR6129 Gene

GeneLoc Exon Structure for
MIR6129

No data available for mRNA/cDNA for MIR6129 Gene

Expression for MIR6129 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6129 Gene

Orthologs for MIR6129 Gene

Evolution for MIR6129 Gene

ENSEMBL:
Gene Tree for MIR6129 (if available)
TreeFam:
Gene Tree for MIR6129 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR6129

No data available for Orthologs for MIR6129 Gene

Paralogs for MIR6129 Gene

No data available for Paralogs for MIR6129 Gene

Variants for MIR6129 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6129 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR6129 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6129
Leiden Open Variation Database (LOVD)
MIR6129

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6129 Gene

Disorders for MIR6129 Gene

Additional Disease Information for MIR6129

No disorders were found for MIR6129 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6129 Gene

Publications for MIR6129 Gene

  1. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M … Kelso J (Genome biology and evolution 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6129 Gene

Sources for MIR6129 Gene