microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6124 Gene

Subcategory (RNA class) for MIR6124 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6124 Gene

  • MicroRNA 6124 2 3 5
  • Hsa-Mir-6124 2 3
  • MIR6124 2 5
  • MicroRNA Mir-6124 3
  • MIMAT0024597 50
  • MI0021258 50

External Ids for MIR6124 Gene

Previous GeneCards Identifiers for MIR6124 Gene

  • GC11U902215

Summaries for MIR6124 Gene

Entrez Gene Summary for MIR6124 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6124 Gene

MIR6124 (MicroRNA 6124) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6124 include Pyuria.

Additional gene information for MIR6124 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6124 Gene

Genomics for MIR6124 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6124 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J012155 Promoter/Enhancer 2.1 VISTA FANTOM5 Ensembl ENCODE dbSUPER 0.4 +10.3 10298 36.4 ARHGAP35 SP1 PRDM10 ZNF629 RFX1 LEF1 IKZF1 KDM1A ZNF692 BACH1 MICAL2 MICALCL MN309334 LOC107984312 MIR6124 PARVA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6124 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6124 Gene

Genomic Locations for MIR6124 Gene
chr11:12,163,683-12,163,767
(GRCh38/hg38)
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR6124 Gene

Genes around MIR6124 on UCSC Golden Path with GeneCards custom track
MIR6124 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6124 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6124 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6124 Gene

Proteins for MIR6124 Gene

Post-translational modifications for MIR6124 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6124 Gene

Domains & Families for MIR6124 Gene

Gene Families for MIR6124 Gene

HGNC:
genes like me logo Genes that share domains with MIR6124: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6124 Gene

Function for MIR6124 Gene

Phenotypes From GWAS Catalog for MIR6124 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6124 Gene

Localization for MIR6124 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6124 Gene

Pathways & Interactions for MIR6124 Gene

PathCards logo

SuperPathways for MIR6124 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6124 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6124 Gene

Drugs & Compounds for MIR6124 Gene

No Compound Related Data Available

Transcripts for MIR6124 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6124 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BAD8_9606 precursor_RNA 85 4

HGNC: 50200,

RefSeq: NR_106739,

Ensembl: ENST00000617177 (view in UCSC) ,

miRBase: MI0021258,

URS000075CC26_9606 miRNA 20 2

RefSeq: NR_106739,

miRBase: MIMAT0024597,

MIR6124 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6124 Gene

No ASD Table

Relevant External Links for MIR6124 Gene

GeneLoc Exon Structure for
MIR6124

No data available for mRNA/cDNA for MIR6124 Gene

Expression for MIR6124 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6124 Gene

Orthologs for MIR6124 Gene

Evolution for MIR6124 Gene

ENSEMBL:
Gene Tree for MIR6124 (if available)
TreeFam:
Gene Tree for MIR6124 (if available)

No data available for Orthologs for MIR6124 Gene

Paralogs for MIR6124 Gene

No data available for Paralogs for MIR6124 Gene

Variants for MIR6124 Gene

Additional dbSNP identifiers (rs#s) for MIR6124 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6124 Gene

Variant ID Type Subtype PubMed ID
nsv483000 CNV loss 15286789
nsv832068 CNV gain 17160897

Additional Variant Information for MIR6124 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6124

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6124 Gene

Disorders for MIR6124 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6124 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pyuria
  • pus cells in urine
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6124

genes like me logo Genes that share disorders with MIR6124: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6124 Gene

Publications for MIR6124 Gene

  1. Analysis of Purines and Pyrimidines distribution over miRNAs of Human, Gorilla, Chimpanzee, Mouse and Rat. (PMID: 29967426) Das JK … Basu P (Scientific reports 2018) 3
  2. Induction of the cellular microRNA, Hs_154, by West Nile virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors. (PMID: 22345437) Smith JL … Hirsch AJ (Journal of virology 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6124 Gene

Sources for MIR6124 Gene