microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6081 Gene

Subcategory (RNA class) for MIR6081 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6081 Gene

  • MicroRNA 6081 2 3 5
  • Hsa-Mir-6081 2 3
  • MIR6081 2 5
  • MicroRNA Mir-6081 3
  • MIMAT0023706 50
  • MI0020358 50

External Ids for MIR6081 Gene

Previous GeneCards Identifiers for MIR6081 Gene

  • GC09U902153

Summaries for MIR6081 Gene

Entrez Gene Summary for MIR6081 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6081 Gene

MIR6081 (MicroRNA 6081) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6081 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6081 Gene

Genomics for MIR6081 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6081 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J095060 Enhancer 1.2 Ensembl ENCODE dbSUPER 600.7 -1.3 -1254 6.2 GATAD2A TFE3 RXRB IRF2 SP1 GABPA TOE1 CEBPA FOXK2 SOX13 MIR6081 MIR23B MIR27B MIR3074 AOPEP piR-43107-304 NONHSAG052915.2 FANCC
GH09J095067 Enhancer 1 Ensembl ENCODE dbSUPER 0.7 +4.2 4151 3.4 GATAD2A RCOR2 CEBPA CEBPB ZBTB26 FOXA2 EP300 TEAD1 RBM22 FOXP1 MIR6081 MIR23B NONHSAG052915.2 FANCC AOPEP
GH09J095047 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -15.6 -15615 4.5 PRDM10 IKZF1 PRDM1 MTA2 PHF21A RBFOX2 PKNOX1 REST ZNF501 HDAC1 FBP1 piR-43107-304 MIR6081 NONHSAG052915.2 AOPEP FANCC
GH09J095053 Promoter/Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -8.5 -8478 6.2 PRDM10 ZNF629 FOXA1 ZIC2 POLR2A ZBTB44 SP1 TCF7L2 CEBPB OSR2 MIR23B MIR27B MIR3074 MIR6081 piR-43107-304 NONHSAG052915.2 AOPEP FANCC
GH09J095076 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +14.1 14051 7.6 ATF7 TEAD4 ZIC2 ESR1 ATF3 POLR2A RBM22 ZFHX2 CTCF GATA3 FANCC AOPEP PTCH1 MIR23B MIR6081 NONHSAG052915.2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6081 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6081 Gene

Genomic Locations for MIR6081 Gene
chr9:95,065,350-95,065,446
(GRCh38/hg38)
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR6081 Gene

Genes around MIR6081 on UCSC Golden Path with GeneCards custom track
MIR6081 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6081 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6081 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6081 Gene

Proteins for MIR6081 Gene

Post-translational modifications for MIR6081 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6081 Gene

Domains & Families for MIR6081 Gene

Gene Families for MIR6081 Gene

HGNC:
genes like me logo Genes that share domains with MIR6081: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6081 Gene

Function for MIR6081 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6081 Gene

Localization for MIR6081 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6081 Gene

Pathways & Interactions for MIR6081 Gene

PathCards logo

SuperPathways for MIR6081 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6081 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6081 Gene

Drugs & Compounds for MIR6081 Gene

No Compound Related Data Available

Transcripts for MIR6081 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6081 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E2FC_9606 precursor_RNA 97 4

HGNC: 50151,

RefSeq: NR_106729,

Ensembl: ENST00000613785 (view in UCSC) ,

miRBase: MI0020358,

URS0000759AA7_9606 miRNA 24 2

RefSeq: NR_106729,

miRBase: MIMAT0023706,

MIR6081 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6081 Gene

No ASD Table

Relevant External Links for MIR6081 Gene

GeneLoc Exon Structure for
MIR6081

No data available for mRNA/cDNA for MIR6081 Gene

Expression for MIR6081 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6081 Gene

Orthologs for MIR6081 Gene

Evolution for MIR6081 Gene

ENSEMBL:
Gene Tree for MIR6081 (if available)
TreeFam:
Gene Tree for MIR6081 (if available)

No data available for Orthologs for MIR6081 Gene

Paralogs for MIR6081 Gene

No data available for Paralogs for MIR6081 Gene

Variants for MIR6081 Gene

Additional dbSNP identifiers (rs#s) for MIR6081 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6081 Gene

Variant ID Type Subtype PubMed ID
nsv1038106 CNV gain 25217958
nsv1147999 OTHER inversion 26484159

Additional Variant Information for MIR6081 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6081

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6081 Gene

Disorders for MIR6081 Gene

No disorders were found for MIR6081 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6081 Gene

Publications for MIR6081 Gene

  1. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C … Martelli F (RNA (New York, N.Y.) 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6081 Gene

Sources for MIR6081 Gene