microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6077 Gene

Subcategory (RNA class) for MIR6077 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR6077 Gene

  • MicroRNA 6077 2 3 5
  • MicroRNA 6077-1 2 3
  • MicroRNA 6077-2 2 3
  • MicroRNA Mir-6077-1 3
  • MicroRNA Mir-6077-2 3
  • Hsa-Mir-6077-1 3
  • Hsa-Mir-6077-2 3
  • Hsa-Mir-6077 3
  • MIMAT0023702 51
  • MIR6077-1 3
  • MIR6077-2 3
  • MI0020354 51
  • MIR6077 2

External Ids for MIR6077 Gene

Previous HGNC Symbols for MIR6077 Gene

  • MIR6077-2
  • MIR6077-1

Summaries for MIR6077 Gene

Entrez Gene Summary for MIR6077 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6077 Gene

MIR6077 (MicroRNA 6077) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6077 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6077 Gene

Genomics for MIR6077 Gene

GeneHancer (GH) Regulatory Elements for MIR6077 Gene

Promoters and enhancers for MIR6077 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J148388 Promoter 0.3 Ensembl 500.7 +0.2 219 2.2 ENSG00000238825 MIR6077 RNVU1-2 LINC01138
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6077 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6077 Gene

Genomic Locations for MIR6077 Gene
chr1:148,388,282-148,388,363
(GRCh38/hg38)
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR6077 Gene

Genes around MIR6077 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6077 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6077 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6077 Gene

Proteins for MIR6077 Gene

Post-translational modifications for MIR6077 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6077 Gene

Domains & Families for MIR6077 Gene

Gene Families for MIR6077 Gene

HGNC:
genes like me logo Genes that share domains with MIR6077: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6077 Gene

Function for MIR6077 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6077 Gene

Localization for MIR6077 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6077 Gene

Pathways & Interactions for MIR6077 Gene

PathCards logo

SuperPathways for MIR6077 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR6077 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6077 Gene

Drugs & Compounds for MIR6077 Gene

No Compound Related Data Available

Transcripts for MIR6077 Gene

mRNA/cDNA for MIR6077 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6077 Gene

No ASD Table

Relevant External Links for MIR6077 Gene

GeneLoc Exon Structure for
MIR6077

Expression for MIR6077 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6077 Gene

Orthologs for MIR6077 Gene

Evolution for MIR6077 Gene

ENSEMBL:
Gene Tree for MIR6077 (if available)
TreeFam:
Gene Tree for MIR6077 (if available)

No data available for Orthologs for MIR6077 Gene

Paralogs for MIR6077 Gene

No data available for Paralogs for MIR6077 Gene

Variants for MIR6077 Gene

Additional dbSNP identifiers (rs#s) for MIR6077 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6077 Gene

Variant ID Type Subtype PubMed ID
dgv187n106 CNV deletion 24896259
dgv327n100 CNV gain 25217958
dgv66e199 CNV deletion 23128226
dgv68e199 CNV deletion 23128226
esv2667036 CNV deletion 23128226
esv2677125 CNV deletion 23128226
esv2761299 CNV gain+loss 21179565
esv27827 CNV gain 19812545
esv3572675 CNV gain 25503493
nsv1003688 CNV gain 25217958
nsv1005055 CNV loss 25217958
nsv1078224 CNV deletion 25765185
nsv1132304 CNV duplication 24896259
nsv509457 CNV insertion 20534489
nsv510962 OTHER complex 20534489
nsv510984 OTHER inversion 20534489
nsv547650 CNV loss 21841781
nsv8214 CNV gain 18304495
nsv831448 CNV loss 17160897
nsv946218 CNV duplication 23825009
nsv946327 CNV duplication 23825009
nsv951837 CNV deletion 24416366

Additional Variant Information for MIR6077 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6077

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6077 Gene

Disorders for MIR6077 Gene

Additional Disease Information for MIR6077

No disorders were found for MIR6077 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6077 Gene

Publications for MIR6077 Gene

  1. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C … Martelli F (RNA (New York, N.Y.) 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6077 Gene

Sources for MIR6077 Gene