microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR607 Gene

Subcategory (RNA class) for MIR607 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR607 Gene

  • MicroRNA 607 2 3 5
  • Hsa-MiR-607 166 177
  • MIMAT0003275 51
  • Hsa-Mir-607 3
  • MI0003620 51
  • MIRN607 3
  • RF00974 172
  • MIR607 2

External Ids for MIR607 Gene

Previous HGNC Symbols for MIR607 Gene

  • MIRN607

Previous GeneCards Identifiers for MIR607 Gene

  • GC10M098579

Summaries for MIR607 Gene

Entrez Gene Summary for MIR607 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR607 Gene

MIR607 (MicroRNA 607) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR607 Gene

Additional gene information for MIR607 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR607 Gene

Genomics for MIR607 Gene

GeneHancer (GH) Regulatory Elements for MIR607 Gene

Promoters and enhancers for MIR607 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J096586 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 10.6 +242.1 242100 5.3 ZBTB40 EP300 TCF12 POLR2G GTF2E2 PHF8 JUND FOS ZFX POLR2A LOC105378443 TM9SF3 lnc-LCOR-4 lnc-PIK3AP1-1 NPM1P26 MIR607 LCOR piR-34822-047
GH10J096737 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE dbSUPER 10.8 +90.5 90463 1.8 ZBTB40 NRF1 POLR2A MEF2B NBN SPI1 ELF1 TBX21 TAF1 BHLHE40 LCOR piR-32559-056 MIR607 RF00026-163 RNU6-1274P
GH10J096699 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 11.5 +126.9 126869 5.4 ZBTB40 EP300 RELA MEF2C TRIM22 POLR2A BCL11A TCF12 SRF ARNT RNU6-1274P MIR607 LCOR RF00017-758 piR-36245-001 PIK3AP1
GH10J096640 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.9 +187.6 187573 0.8 ZNF217 CTCF NRF1 REST MYC TGIF2 RAD21 TRIM22 SMC3 MCM3 NPM1P26 PIK3AP1 TCTN3 MIR607 LCOR TM9SF3 RPL13AP5 CCNJ EXOSC1 lnc-TM9SF3-2
GH10J096862 Enhancer 1.1 Ensembl ENCODE 12.3 -35.6 -35618 4.4 ZNF217 TCF12 NCOR1 JUND KDM6A TCF7 FOXA1 CUX1 SKI JUN LCOR MIR607 FRAT1 RF00017-759 lnc-FRAT1-7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR607 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR607 Gene

Genomic Locations for MIR607 Gene
chr10:96,828,669-96,828,764
(GRCh38/hg38)
Size:
96 bases
Orientation:
Minus strand
chr10:98,588,426-98,588,521
(GRCh37/hg19)
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR607 Gene

Genes around MIR607 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR607 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR607 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR607 Gene

Proteins for MIR607 Gene

Post-translational modifications for MIR607 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR607 Gene

Domains & Families for MIR607 Gene

Gene Families for MIR607 Gene

HGNC:
genes like me logo Genes that share domains with MIR607: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR607 Gene

Function for MIR607 Gene

Phenotypes From GWAS Catalog for MIR607 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR607 Gene

Localization for MIR607 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR607 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR607 Gene

Pathways & Interactions for MIR607 Gene

PathCards logo

SuperPathways for MIR607 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR607 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR607 Gene

Drugs & Compounds for MIR607 Gene

No Compound Related Data Available

Transcripts for MIR607 Gene

mRNA/cDNA for MIR607 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :
1 Rfam transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR607 Gene

No ASD Table

Relevant External Links for MIR607 Gene

GeneLoc Exon Structure for
MIR607

Expression for MIR607 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR607

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR607 Gene

Orthologs for MIR607 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR607 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 99 (a)
OneToOne
Species where no ortholog for MIR607 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR607 Gene

ENSEMBL:
Gene Tree for MIR607 (if available)
TreeFam:
Gene Tree for MIR607 (if available)

Paralogs for MIR607 Gene

No data available for Paralogs for MIR607 Gene

Variants for MIR607 Gene

Additional dbSNP identifiers (rs#s) for MIR607 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR607 Gene

Variant ID Type Subtype PubMed ID
esv3577638 CNV gain 25503493
nsv1053801 CNV gain 25217958
nsv1110852 OTHER inversion 24896259
nsv825532 CNV gain 20364138

Additional Variant Information for MIR607 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR607

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR607 Gene

Disorders for MIR607 Gene

Additional Disease Information for MIR607

No disorders were found for MIR607 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR607 Gene

Publications for MIR607 Gene

  1. Circular RNA circ-CBFB promotes proliferation and inhibits apoptosis in chronic lymphocytic leukemia through regulating miR-607/FZD3/Wnt/β-catenin pathway. (PMID: 29902450) Xia L … Xia R (Biochemical and biophysical research communications 2018) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54
  3. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 54
  4. Long non‑coding RNA TP73 antisense RNA 1 facilitates the proliferation and migration of cervical cancer cells via regulating microRNA‑607/cyclin D2. (PMID: 31432138) Zhang H … Fan T (Molecular medicine reports 2019) 3

Products for MIR607 Gene

Sources for MIR607 Gene