microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6069 Gene

Subcategory (RNA class) for MIR6069 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6069 Gene

  • MicroRNA 6069 2 3 5
  • Hsa-Mir-6069 2 3
  • MIR6069 2 5
  • MicroRNA Mir-6069 3
  • MIMAT0023694 50
  • MI0020346 50

External Ids for MIR6069 Gene

Previous GeneCards Identifiers for MIR6069 Gene

  • GC22U901022

Summaries for MIR6069 Gene

Entrez Gene Summary for MIR6069 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6069 Gene

MIR6069 (MicroRNA 6069) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6069 include Brucellosis.

Additional gene information for MIR6069 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6069 Gene

Genomics for MIR6069 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6069 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J035335 Enhancer 0.5 ENCODE 600.7 +0.7 720 1.6 ZNF629 ZNF692 JUND ZIC2 ZNF189 ZFP69B ATF3 ATF2 ATF7 MIR3909 MIR6069 MB TOM1 HMOX1
GH22J035337 Enhancer 0.4 ENCODE 600.7 -1.3 -1264 0.3 RFX5 CTCF RAD21 MIR6069 TOM1 RASD2 MB lnc-HMOX1-2 HMOX1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6069 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6069 Gene

Genomic Locations for MIR6069 Gene
chr22:35,336,721-35,336,799
(GRCh38/hg38)
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR6069 Gene

Genes around MIR6069 on UCSC Golden Path with GeneCards custom track
MIR6069 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6069 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6069 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6069 Gene

Proteins for MIR6069 Gene

Post-translational modifications for MIR6069 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6069 Gene

Domains & Families for MIR6069 Gene

Gene Families for MIR6069 Gene

HGNC:
genes like me logo Genes that share domains with MIR6069: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6069 Gene

Function for MIR6069 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6069 Gene

Localization for MIR6069 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6069 Gene

Pathways & Interactions for MIR6069 Gene

PathCards logo

SuperPathways for MIR6069 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6069 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6069 Gene

Drugs & Compounds for MIR6069 Gene

No Compound Related Data Available

Transcripts for MIR6069 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6069 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DCF8_9606 precursor_RNA 79 4

HGNC: 50124,

RefSeq: NR_106717,

Ensembl: ENST00000620069 (view in UCSC) ,

miRBase: MI0020346,

URS000075DD02_9606 miRNA 21 2

RefSeq: NR_106717,

miRBase: MIMAT0023694,

MIR6069 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6069 Gene

No ASD Table

Relevant External Links for MIR6069 Gene

GeneLoc Exon Structure for
MIR6069

No data available for mRNA/cDNA for MIR6069 Gene

Expression for MIR6069 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6069 Gene

Orthologs for MIR6069 Gene

Evolution for MIR6069 Gene

ENSEMBL:
Gene Tree for MIR6069 (if available)
TreeFam:
Gene Tree for MIR6069 (if available)

No data available for Orthologs for MIR6069 Gene

Paralogs for MIR6069 Gene

No data available for Paralogs for MIR6069 Gene

Variants for MIR6069 Gene

Additional dbSNP identifiers (rs#s) for MIR6069 Gene

Additional Variant Information for MIR6069 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6069

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR6069 Gene

Disorders for MIR6069 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6069 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
brucellosis
  • bang's disease
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6069

genes like me logo Genes that share disorders with MIR6069: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6069 Gene

Publications for MIR6069 Gene

  1. Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis. (PMID: 27722176) Budak F … Oral HB (Journal of immunology research 2016) 3
  2. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C … Martelli F (RNA (New York, N.Y.) 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6069 Gene

Sources for MIR6069 Gene