microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR606 Gene

Subcategory (RNA class) for MIR606 Gene

miRNA

Number of RNA Genes sources:

3 / 14

Aliases for MIR606 Gene

  • MicroRNA 606 2 3 5
  • Hsa-MiR-606 166 177
  • MIMAT0003274 51
  • Hsa-Mir-606 3
  • MI0003619 51
  • MIRN606 3
  • MIR606 2

External Ids for MIR606 Gene

Previous HGNC Symbols for MIR606 Gene

  • MIRN606

Previous GeneCards Identifiers for MIR606 Gene

  • GC10P076983
  • GC10P077312

Summaries for MIR606 Gene

Entrez Gene Summary for MIR606 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR606 Gene

MIR606 (MicroRNA 606) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR606 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR606 Gene

Genomics for MIR606 Gene

GeneHancer (GH) Regulatory Elements for MIR606 Gene

Promoters and enhancers for MIR606 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J075553 Enhancer 0.3 Ensembl 500.7 +1.3 1343 1.2 SPI1 MIR606 LRMDA piR-58308-041
GH10J075507 Enhancer 1.7 UCNEbase Ensembl ENCODE CraniofacialAtlas dbSUPER 11.5 -40.6 -40557 12.6 EP300 ZSCAN5C JUND REST KLF7 ATF2 MXI1 ZNF341 OSR2 NR2F2 LRMDA MIR606 ENSG00000236842 piR-55194-047 HSALNG0078972
GH10J075612 Enhancer 1.4 UCNEbase ENCODE CraniofacialAtlas 10.9 +61.5 61481 2.1 ZSCAN5C ZNF639 ZNF10 EP300 ZIC2 ZBTB10 ZNF423 ZNF623 TRIM28 KLF7 LRMDA MIR606 ENSG00000236842 ZNF503 ZNF503-AS2 5MWI_A-018 ENSG00000286715
GH10J075451 Enhancer 1.3 UCNEbase Ensembl ENCODE CraniofacialAtlas 10.5 -102.1 -102057 4 EP300 KLF9 NANOG CEBPB ZFHX2 ZBTB48 KLF17 ZNF624 GLIS1 KLF1 ENSG00000279814 LRMDA MIR606 HSALNG0078972
GH10J075468 Enhancer 1.2 Ensembl ENCODE dbSUPER 10.4 -81.9 -81857 5.2 TCF12 JUND FOS ZBTB10 KLF7 EP300 ATF2 ZEB1 OSR2 NR2F2 KAT6B LRMDA ENSG00000236842 ZNF503 ZNF503-AS2 MIR606 HSALNG0078972 ENSG00000279814
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR606 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR606 Gene

Genomic Locations for MIR606 Gene
chr10:75,552,458-75,552,553
(GRCh38/hg38)
Size:
96 bases
Orientation:
Plus strand
chr10:77,312,216-77,312,311
(GRCh37/hg19)
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR606 Gene

Genes around MIR606 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR606 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR606 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR606 Gene

Proteins for MIR606 Gene

Post-translational modifications for MIR606 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR606 Gene

Domains & Families for MIR606 Gene

Gene Families for MIR606 Gene

HGNC:
genes like me logo Genes that share domains with MIR606: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR606 Gene

Function for MIR606 Gene

Phenotypes From GWAS Catalog for MIR606 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR606 Gene

Localization for MIR606 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR606 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR606 Gene

Pathways & Interactions for MIR606 Gene

PathCards logo

SuperPathways for MIR606 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR606 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR606 Gene

Drugs & Compounds for MIR606 Gene

No Compound Related Data Available

Transcripts for MIR606 Gene

mRNA/cDNA for MIR606 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR606 Gene

No ASD Table

Relevant External Links for MIR606 Gene

GeneLoc Exon Structure for
MIR606

Expression for MIR606 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR606 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR606

genes like me logo Genes that share expression patterns with MIR606: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR606 Gene

Orthologs for MIR606 Gene

Evolution for MIR606 Gene

ENSEMBL:
Gene Tree for MIR606 (if available)
TreeFam:
Gene Tree for MIR606 (if available)

No data available for Orthologs for MIR606 Gene

Paralogs for MIR606 Gene

No data available for Paralogs for MIR606 Gene

Variants for MIR606 Gene

Additional dbSNP identifiers (rs#s) for MIR606 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR606 Gene

Variant ID Type Subtype PubMed ID
esv2759768 CNV gain+loss 17122850
nsv1036391 CNV gain 25217958

Additional Variant Information for MIR606 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR606

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR606 Gene

Disorders for MIR606 Gene

Additional Disease Information for MIR606

No disorders were found for MIR606 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR606 Gene

Publications for MIR606 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54
  2. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 54

Products for MIR606 Gene

Sources for MIR606 Gene