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Aliases for MIR603 Gene

Subcategory (RNA class) for MIR603 Gene


Quality Score for this RNA gene is


Aliases for MIR603 Gene

  • MicroRNA 603 2 3 5
  • Hsa-Mir-603 3
  • MIRN603 3

External Ids for MIR603 Gene

ORGUL Members for MIR603 Gene

Previous HGNC Symbols for MIR603 Gene

  • MIRN603

Previous GeneCards Identifiers for MIR603 Gene

  • GC10P024605

Summaries for MIR603 Gene

Entrez Gene Summary for MIR603 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR603 Gene

MIR603 (MicroRNA 603) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR603 include Vulva Cancer.

Additional gene information for MIR603 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR603 Gene

Genomics for MIR603 Gene

Genomic Locations for MIR603 Gene

Genomic Locations for MIR603 Gene
97 bases
Plus strand

Genomic View for MIR603 Gene

Genes around MIR603 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR603 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR603 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR603 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR603 Gene

Proteins for MIR603 Gene

Post-translational modifications for MIR603 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR603 Gene

Domains & Families for MIR603 Gene

Gene Families for MIR603 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR603: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR603 Gene

Function for MIR603 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR603 Gene

Localization for MIR603 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR603 Gene

Pathways & Interactions for MIR603 Gene

SuperPathways for MIR603 Gene

No Data Available

Interacting Proteins for MIR603 Gene

Gene Ontology (GO) - Biological Process for MIR603 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR603 Gene

Drugs & Compounds for MIR603 Gene

No Compound Related Data Available

Transcripts for MIR603 Gene

mRNA/cDNA for MIR603 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR603 Gene

No ASD Table

Relevant External Links for MIR603 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR603 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR603 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR603 Gene:

genes like me logo Genes that share expression patterns with MIR603: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR603 Gene

Orthologs for MIR603 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR603 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 98 (a)
Species where no ortholog for MIR603 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR603 Gene

Gene Tree for MIR603 (if available)
Gene Tree for MIR603 (if available)

Paralogs for MIR603 Gene

No data available for Paralogs for MIR603 Gene

Variants for MIR603 Gene

Sequence variations from dbSNP and Humsavar for MIR603 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000081449 -- 24,273,981(+) G/A upstream_transcript_variant
rs1000466471 -- 24,276,100(+) C/T downstream_transcript_variant
rs1001062969 -- 24,274,935(+) T/C upstream_transcript_variant
rs1003348063 -- 24,275,260(+) G/T upstream_transcript_variant
rs1004179142 -- 24,274,785(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR603 Gene

Variant ID Type Subtype PubMed ID
nsv520378 CNV loss 19592680

Additional Variant Information for MIR603 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR603 Gene

Disorders for MIR603 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR603 Gene - From: DISEASES

Disorder Aliases PubMed IDs
vulva cancer
  • ca vulva
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR603

genes like me logo Genes that share disorders with MIR603: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR603 Gene

Publications for MIR603 Gene

  1. Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease. (PMID: 26856603) Zhang C … Wang Y (Aging 2016) 3 58
  2. MicroRNA-603 functions as an oncogene by suppressing BRCC2 protein translation in osteosarcoma. (PMID: 27035098) Ma C … Zhang Z (Oncology reports 2016) 3 58
  3. miR-603 promotes glioma cell growth via Wnt/β-catenin pathway by inhibiting WIF1 and CTNNBIP1. (PMID: 25681036) Guo M … Zheng Y (Cancer letters 2015) 3 58
  4. The Functional Variant in the 3'UTR of IGF1 with the Risk of Gastric Cancer in a Chinese Population. (PMID: 26068646) Jiang H … Chen S (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015) 3 58
  5. Association study of hsa-mir-603 rs11014002 polymorphism and risk of breast cancer in a sample of Iranian population. (PMID: 26718432) Hashemi M … Ghavami S (Cellular and molecular biology (Noisy-le-Grand, France) 2015) 3 58

Products for MIR603 Gene

Sources for MIR603 Gene

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