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Aliases for MIR576 Gene

Subcategory (RNA class) for MIR576 Gene


Quality Score for this RNA gene is


Aliases for MIR576 Gene

  • MicroRNA 576 2 3 5
  • Hsa-Mir-576 3
  • MIRN576 3

External Ids for MIR576 Gene

ORGUL Members for MIR576 Gene

Previous HGNC Symbols for MIR576 Gene

  • MIRN576

Previous GeneCards Identifiers for MIR576 Gene

  • GC04P110630
  • GC04P110409

Summaries for MIR576 Gene

Entrez Gene Summary for MIR576 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR576 Gene

MIR576 (MicroRNA 576) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR576 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR576 Gene

Genomics for MIR576 Gene

GeneHancer (GH) Regulatory Elements for MIR576 Gene

Promoters and enhancers for MIR576 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I109548 Enhancer 0.9 FANTOM5 Ensembl ENCODE 0.2 +60.1 60102 1.4 JUND ZNF316 JUN MAFK EMSY CFI MCUB RBMXP4 SEC24B SETP20 MIR576
GH04I109528 Enhancer 0.3 FANTOM5 0.3 +39.8 39780 0.2 SEC24B SETP20 MIR576
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR576 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR576 Gene

Genomic Locations for MIR576 Gene
98 bases
Plus strand

Genomic View for MIR576 Gene

Genes around MIR576 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR576 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR576 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR576 Gene

Proteins for MIR576 Gene

Post-translational modifications for MIR576 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR576 Gene

Domains & Families for MIR576 Gene

Gene Families for MIR576 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR576: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR576 Gene

Function for MIR576 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR576 Gene

Localization for MIR576 Gene

Gene Ontology (GO) - Cellular Components for MIR576 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR576: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR576 Gene

Pathways & Interactions for MIR576 Gene

SuperPathways for MIR576 Gene

No Data Available

Interacting Proteins for MIR576 Gene

Gene Ontology (GO) - Biological Process for MIR576 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR576 Gene

Drugs & Compounds for MIR576 Gene

No Compound Related Data Available

Transcripts for MIR576 Gene

mRNA/cDNA for MIR576 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR576 Gene

No ASD Table

Relevant External Links for MIR576 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR576 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR576 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR576 Gene:

genes like me logo Genes that share expression patterns with MIR576: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR576 Gene

Orthologs for MIR576 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR576 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-576 34
  • 97 (a)
(Bos Taurus)
Mammalia -- 34
  • 63 (a)
Species where no ortholog for MIR576 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR576 Gene

Gene Tree for MIR576 (if available)
Gene Tree for MIR576 (if available)

Paralogs for MIR576 Gene

No data available for Paralogs for MIR576 Gene

Variants for MIR576 Gene

Sequence variations from dbSNP and Humsavar for MIR576 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000917498 -- 109,488,432(+) A/T upstream_transcript_variant
rs1001659583 -- 109,487,059(+) G/A upstream_transcript_variant
rs1001730766 -- 109,486,889(+) G/A upstream_transcript_variant
rs1004044178 -- 109,489,061(+) T/C downstream_transcript_variant
rs1005767720 -- 109,487,396(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR576 Gene

Variant ID Type Subtype PubMed ID
nsv461613 CNV gain 19166990
nsv525385 CNV loss 19592680
nsv595129 CNV gain 21841781

Additional Variant Information for MIR576 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR576 Gene

Disorders for MIR576 Gene

Additional Disease Information for MIR576

No disorders were found for MIR576 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR576 Gene

Publications for MIR576 Gene

  1. MiR-576-3p is a novel marker correlated with poor clinical outcome in bladder cancer. (PMID: 28338199) Meng FM … Song XL (European review for medical and pharmacological sciences 2017) 3 58
  2. Epigenetic downregulated ITGBL1 promotes non-small cell lung cancer cell invasion through Wnt/PCP signaling. (PMID: 26307393) Gan X … Zhou J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 58
  3. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  4. MicroRNA-576-3p inhibits proliferation in bladder cancer cells by targeting cyclin D1. (PMID: 25556372) Liang Z … Xie L (Molecules and cells 2015) 3 58
  5. Primate-specific miR-576-3p sets host defense signalling threshold. (PMID: 25232931) Yarbrough ML … Fontoura BM (Nature communications 2014) 3 58

Products for MIR576 Gene

Sources for MIR576 Gene

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