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Aliases for MIR573 Gene

Subcategory (RNA class) for MIR573 Gene


Quality Score for this RNA gene is


Aliases for MIR573 Gene

  • MicroRNA 573 2 3 5
  • Hsa-Mir-573 3
  • Mir-573 3
  • MIRN573 3

External Ids for MIR573 Gene

Previous HGNC Symbols for MIR573 Gene

  • MIRN573

Previous GeneCards Identifiers for MIR573 Gene

  • GC04M024131

Summaries for MIR573 Gene

Entrez Gene Summary for MIR573 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR573 Gene

MIR573 (MicroRNA 573) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR573 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR573

Additional gene information for MIR573 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR573 Gene

Genomics for MIR573 Gene

GeneHancer (GH) Regulatory Elements for MIR573 Gene

Promoters and enhancers for MIR573 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I024469 Enhancer 1.5 FANTOM5 Ensembl ENCODE 10.8 +48.6 48594 4.2 ATF1 SIN3A FEZF1 GLI4 ZNF2 ZNF121 ZNF766 GLIS2 ZNF143 KLF7 PPARGC1A DHX15 ZCCHC4 ANAPC4 MIR573 LINC02473 GC04P024448
GH04I024488 Enhancer 0.6 ENCODE 10.9 +31.4 31417 0.2 CTCF ZNF654 ZNF189 TRIM22 REST RAD21 ZNF143 SMC3 PRDM10 ZNF444 MIR573 DHX15 PPARGC1A
GH04I024687 Enhancer 0.6 ENCODE 10.2 -167.1 -167060 0.6 CTCF PKNOX1 ATF1 RB1 TRIM22 ZNF384 REST RAD21 GATA3 GATA2 DHX15 MIR573 SOD3 LINC02473 PIR57270
GH04I024489 Enhancer 0.3 ENCODE 10.9 +30.9 30920 0.2 CTCF MIR573 DHX15 PPARGC1A
GH04I024490 Enhancer 0.2 ENCODE 11.4 +30.1 30132 0.6 MIR573 PPARGC1A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR573 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR573 Gene

Genomic Locations for MIR573 Gene
99 bases
Minus strand

Genomic View for MIR573 Gene

Genes around MIR573 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR573 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR573 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR573 Gene

ORGUL Member Location for MIR573 Gene

ORGUL Member Location for MIR573 gene

Proteins for MIR573 Gene

Post-translational modifications for MIR573 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR573 Gene

Domains & Families for MIR573 Gene

Gene Families for MIR573 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR573: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR573 Gene

Function for MIR573 Gene

Phenotypes From GWAS Catalog for MIR573 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR573 Gene

Localization for MIR573 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR573 Gene

Pathways & Interactions for MIR573 Gene

SuperPathways for MIR573 Gene

No Data Available

Interacting Proteins for MIR573 Gene

Gene Ontology (GO) - Biological Process for MIR573 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR573 Gene

Drugs & Compounds for MIR573 Gene

No Compound Related Data Available

Transcripts for MIR573 Gene

fRNAdb Secondary structures for MIR573 Gene

  • FR106335
  • hsa-miR-573_MIMAT0003238_Homo_sapiens_miR-573_mature

mRNA/cDNA for MIR573 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR573 Gene

No ASD Table

Relevant External Links for MIR573 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR573 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR573 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR573 Gene:

genes like me logo Genes that share expression patterns with MIR573: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR573 Gene

Orthologs for MIR573 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR573 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 97 (a)
Species where no ortholog for MIR573 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR573 Gene

Gene Tree for MIR573 (if available)
Gene Tree for MIR573 (if available)

Paralogs for MIR573 Gene

No data available for Paralogs for MIR573 Gene

Variants for MIR573 Gene

Sequence variations from dbSNP and Humsavar for MIR573 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1001256140 -- 24,522,079(-) A/G upstream_transcript_variant
rs10013997 -- 24,521,057(-) A/C upstream_transcript_variant
rs10014000 -- 24,521,065(-) A/C upstream_transcript_variant
rs1002871589 -- 24,520,806(-) G/T upstream_transcript_variant
rs1003335924 -- 24,520,606(-) T/C upstream_transcript_variant

Additional Variant Information for MIR573 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR573 Gene

Disorders for MIR573 Gene

Additional Disease Information for MIR573

No disorders were found for MIR573 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR573 Gene

Publications for MIR573 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. miR-573 is a negative regulator in the pathogenesis of rheumatoid arthritis. (PMID: 26166764) Wang L … Chang X (Cellular & molecular immunology 2016) 3 58
  3. MiR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition. (PMID: 26451614) Wang L … Han B (Oncotarget 2015) 3 58
  4. The miR-573/apoM/Bcl2A1-dependent signal transduction pathway is essential for hepatocyte apoptosis and hepatocarcinogenesis. (PMID: 26201458) Hu YW … Wang Q (Apoptosis : an international journal on programmed cell death 2015) 3 58
  5. TSPAN1 functions as an oncogene in gastric cancer and is downregulated by miR-573. (PMID: 26054975) Lu Z … Xue X (FEBS letters 2015) 3 58

Products for MIR573 Gene

Sources for MIR573 Gene

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