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MIR572 Gene(RNA Gene)

MicroRNA 572

GCID:
GC04P012142
GIFtS:
13
Genes Participants
UDN Logo

Aliases for MIR572 Gene

Subcategory (RNA class) for MIR572 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR572 Gene

  • MicroRNA 572 2 3 5
  • Hsa-Mir-572 3
  • MIRN572 3

External Ids for MIR572 Gene

ORGUL Members for MIR572 Gene

Previous HGNC Symbols for MIR572 Gene

  • MIRN572

Previous GeneCards Identifiers for MIR572 Gene

  • GC04P010981
  • GC04P011370
  • GC04P011376
  • GC04P011381
  • GC04P011483
  • GC04P011505
  • GC04P011664
  • GC04P011820
  • GC04P011984

Summaries for MIR572 Gene

Entrez Gene Summary for MIR572 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR572 Gene

MIR572 (MicroRNA 572) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR572 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR572 Gene

Genomics for MIR572 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR572 Gene

Promoters and enhancers for MIR572 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH04I011368 Promoter 0.5 Ensembl 550.8 +0.4 373 1.2 GC04P012158 RNPS1P1 MIR572 PIR59535
GH04I011371 Enhancer 0.2 Ensembl 0.8 +2.5 2474 0.6 GC04P012242 PIR59535 GC04P012262 RNPS1P1 MIR572
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR572 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR572 Gene

Genomic Locations for MIR572 Gene
chr4:11,368,827-11,368,921
(GRCh38/hg38)
Size:
95 bases
Orientation:
Plus strand
chr4:11,370,451-11,370,545
(GRCh37/hg19)

Genomic View for MIR572 Gene

Genes around MIR572 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR572 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR572 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR572 Gene

Proteins for MIR572 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR572 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR572 Gene

Domains & Families for MIR572 Gene

Gene Families for MIR572 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR572: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR572 Gene

Function for MIR572 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for MIR572 Gene

Gene Ontology (GO) - Molecular Function for MIR572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20190813
genes like me logo Genes that share ontologies with MIR572: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR572 Gene

Localization for MIR572 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR572 Gene

Pathways & Interactions for MIR572 Gene

SuperPathways for MIR572 Gene

PathCards logo More details on SuperPathways for MIR572
No Data Available

Interacting Proteins for MIR572 Gene

Gene Ontology (GO) - Biological Process for MIR572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 20190813
genes like me logo Genes that share ontologies with MIR572: view

No data available for Pathways by source and SIGNOR curated interactions for MIR572 Gene

Drugs & Compounds for MIR572 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR572 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR572 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR572 Gene

No ASD Table

Relevant External Links for MIR572 Gene

GeneLoc Exon Structure for
MIR572
ECgene alternative splicing isoforms for
MIR572

Expression for MIR572 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR572 Gene

mRNA expression in normal human tissues for MIR572 Gene
mRNA expression by GTEx for MIR572 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR572 Gene:

MIR572
genes like me logo Genes that share expression patterns with MIR572: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR572 Gene

Orthologs for MIR572 Gene

Evolution for MIR572 Gene

ENSEMBL:
Gene Tree for MIR572 (if available)
TreeFam:
Gene Tree for MIR572 (if available)

No data available for Orthologs for MIR572 Gene

Paralogs for MIR572 Gene

No data available for Paralogs for MIR572 Gene

Variants for MIR572 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for MIR572 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000794037 -- 11,369,419(+) C/A/T downstream_transcript_variant
rs1002503384 -- 11,368,391(+) C/T upstream_transcript_variant
rs1003500153 -- 11,366,932(+) C/T upstream_transcript_variant
rs1003774739 -- 11,367,377(+) A/G upstream_transcript_variant
rs1006627139 -- 11,368,991(+) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR572 Gene

Variant ID Type Subtype PubMed ID
nsv1000613 CNV loss 25217958
nsv1010891 CNV loss 25217958

Additional Variant Information for MIR572 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR572

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR572 Gene

Disorders for MIR572 Gene

Additional Disease Information for MIR572

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR572 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR572 Gene

Publications for MIR572 Gene

  1. Fluoxetine Increases the Expression of miR-572 and miR-663a in Human Neuroblastoma Cell Lines. (PMID: 27716787) Mundalil Vasu M … Suzuki K (PloS one 2016) 3 58
  2. MicroRNA-572 improves early post-operative cognitive dysfunction by down-regulating neural cell adhesion molecule 1. (PMID: 25680004) Yu X … Deng X (PloS one 2015) 3 58
  3. Upregulation of miR-572 transcriptionally suppresses SOCS1 and p21 and contributes to human ovarian cancer progression. (PMID: 25893382) Zhang X … Jiang L (Oncotarget 2015) 3 58
  4. MicroRNA-572 expression in multiple sclerosis patients with different patterns of clinical progression. (PMID: 25947625) Mancuso R … Clerici M (Journal of translational medicine 2015) 3 58
  5. Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. (PMID: 20190813) Wu S … He X (Oncogene 2010) 3 58

Products for MIR572 Gene

Sources for MIR572 Gene

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