microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR572 Gene

Subcategory (RNA class) for MIR572 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR572 Gene

  • MicroRNA 572 2 3 5
  • Hsa-Mir-572 2 3
  • Hsa-MiR-572 163 173
  • MIR572 2 5
  • MIMAT0003237 50
  • MI0003579 50
  • MIRN572 3
  • RF01020 168

External Ids for MIR572 Gene

Previous HGNC Symbols for MIR572 Gene

  • MIRN572

Previous GeneCards Identifiers for MIR572 Gene

  • GC04P010981
  • GC04P011370
  • GC04P011376
  • GC04P011381
  • GC04P012628
  • GC04P012793
  • GC04P012814
  • GC04P013164
  • GC04P011483
  • GC04P011505
  • GC04P011664
  • GC04P011820
  • GC04P011984
  • GC04P012142
  • GC04P012304
  • GC04P012464

Summaries for MIR572 Gene

Entrez Gene Summary for MIR572 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR572 Gene

MIR572 (MicroRNA 572) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR572 include Squamous Cell Carcinoma, Head And Neck and Ovarian Cancer.

Rfam classification for MIR572 Gene

Additional gene information for MIR572 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR572 Gene

Genomics for MIR572 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR572 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J011368 Promoter 0.7 Ensembl CraniofacialAtlas 600.7 +0.4 373 1.6 MIR572 RNPS1P1 piR-39858-468 piR-41525-509 HS3ST1 lnc-DRD5-23-001 CLNK
GH04J011341 Enhancer 0.4 Ensembl 12.8 -26.9 -26926 0.2 TBX21 ATF7 MTA2 RNPS1P1 MIR572 piR-38372-005 lnc-DRD5-8 HS3ST1 lnc-DRD5-23-001 CLNK
GH04J011343 Enhancer 0.3 Ensembl 12.8 -25.3 -25326 1 SMARCA4 RNPS1P1 MIR572 lnc-DRD5-8 piR-38372-005 HS3ST1 lnc-DRD5-23-001 CLNK
GH04J011348 Enhancer 0.2 Ensembl 13 -20.0 -20026 0.8 RNPS1P1 MIR572 HS3ST1 piR-38372-005 lnc-DRD5-8 lnc-DRD5-23-001 CLNK
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR572 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR572 Gene

Genomic Locations for MIR572 Gene
chr4:11,368,827-11,368,921
(GRCh38/hg38)
Size:
95 bases
Orientation:
Plus strand
chr4:11,370,451-11,370,545
(GRCh37/hg19)
Size:
95 bases
Orientation:
Plus strand

Genomic View for MIR572 Gene

Genes around MIR572 on UCSC Golden Path with GeneCards custom track
MIR572 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR572 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR572 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR572 Gene

Proteins for MIR572 Gene

Post-translational modifications for MIR572 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR572 Gene

Domains & Families for MIR572 Gene

Gene Families for MIR572 Gene

HGNC:
genes like me logo Genes that share domains with MIR572: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR572 Gene

Function for MIR572 Gene

Phenotypes From GWAS Catalog for MIR572 Gene

Gene Ontology (GO) - Molecular Function for MIR572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20190813
genes like me logo Genes that share ontologies with MIR572: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR572 Gene

Localization for MIR572 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR572 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR572 Gene

Pathways & Interactions for MIR572 Gene

PathCards logo

SuperPathways for MIR572 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA, IEA --
genes like me logo Genes that share ontologies with MIR572: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR572 Gene

Drugs & Compounds for MIR572 Gene

No Compound Related Data Available

Transcripts for MIR572 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR572 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C548_9606 precursor_RNA 95 4

HGNC: 32828,

RefSeq: NR_030298,

Ensembl: ENST00000384983 (view in UCSC) ,

miRBase: MI0003579,

URS000075CEB8_9606 miRNA 20 4

RefSeq: NR_030298,

LncBase: hsa-miR-572,

miRBase: MIMAT0003237,

TarBase: hsa-miR-572,

URS000067E593_9606 precursor_RNA 56 1

Rfam: RF01020,

MIR572 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR572 Gene

No ASD Table

Relevant External Links for MIR572 Gene

GeneLoc Exon Structure for
MIR572

No data available for mRNA/cDNA for MIR572 Gene

Expression for MIR572 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR572 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR572

genes like me logo Genes that share expression patterns with MIR572: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR572 Gene

Orthologs for MIR572 Gene

Evolution for MIR572 Gene

ENSEMBL:
Gene Tree for MIR572 (if available)
TreeFam:
Gene Tree for MIR572 (if available)

No data available for Orthologs for MIR572 Gene

Paralogs for MIR572 Gene

No data available for Paralogs for MIR572 Gene

Variants for MIR572 Gene

Additional dbSNP identifiers (rs#s) for MIR572 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR572 Gene

Variant ID Type Subtype PubMed ID
nsv1000613 CNV loss 25217958
nsv1010891 CNV loss 25217958

Additional Variant Information for MIR572 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR572

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR572 Gene

Disorders for MIR572 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR572 Gene - From: miR2Disease and DISEASES

Disorder Aliases PubMed IDs
squamous cell carcinoma, head and neck
  • hnscc
ovarian cancer
  • ovarian cancer, somatic
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR572

genes like me logo Genes that share disorders with MIR572: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR572 Gene

Publications for MIR572 Gene

  1. The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1. (PMID: 30317540) Song C … Hu Y (Journal of cellular physiology 2019) 3
  2. microRNA‑572 functions as an oncogene and a potential biomarker for renal cell carcinoma prognosis. (PMID: 30132566) Pan X … Lai Y (Oncology reports 2018) 3
  3. NCAM1 is the Target of miRNA-572: Validation in the Human Oligodendroglial Cell Line. (PMID: 28332001) Mancuso R … Clerici M (Cellular and molecular neurobiology 2018) 3
  4. Interaction between miR-572 and PPP2R2C, and their effects on the proliferation, migration, and invasion of nasopharyngeal carcinoma (NPC) cells. (PMID: 28525724) Yan L … Gui J (Biochemistry and cell biology = Biochimie et biologie cellulaire 2017) 3
  5. Fluoxetine Increases the Expression of miR-572 and miR-663a in Human Neuroblastoma Cell Lines. (PMID: 27716787) Mundalil Vasu M … Suzuki K (PloS one 2016) 3

Products for MIR572 Gene

Sources for MIR572 Gene