microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR571 Gene

Subcategory (RNA class) for MIR571 Gene

miRNA

Number of RNA Genes sources:

3 / 14

Aliases for MIR571 Gene

  • MicroRNA 571 2 3 5
  • Hsa-MiR-571 166 177
  • MIMAT0003236 51
  • Hsa-Mir-571 3
  • MI0003578 51
  • MIRN571 3
  • MIR571 2

External Ids for MIR571 Gene

Previous HGNC Symbols for MIR571 Gene

  • MIRN571

Previous GeneCards Identifiers for MIR571 Gene

  • GC04P000334

Summaries for MIR571 Gene

Entrez Gene Summary for MIR571 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR571 Gene

MIR571 (MicroRNA 571) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR571 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR571 Gene

Genomics for MIR571 Gene

Genomic Locations for MIR571 Gene

Genomic Locations for MIR571 Gene
chr4:350,157-350,252
(GRCh38/hg38)
Size:
96 bases
Orientation:
Plus strand
chr4:343,946-344,041
(GRCh37/hg19)
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR571 Gene

Genes around MIR571 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR571 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR571 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR571 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR571 Gene

Proteins for MIR571 Gene

Post-translational modifications for MIR571 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR571 Gene

Domains & Families for MIR571 Gene

Gene Families for MIR571 Gene

HGNC:
genes like me logo Genes that share domains with MIR571: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR571 Gene

Function for MIR571 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR571 Gene

Localization for MIR571 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR571 gene
Compartment Confidence
plasma membrane 1
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR571 Gene

Pathways & Interactions for MIR571 Gene

PathCards logo

SuperPathways for MIR571 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR571 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR571 Gene

Drugs & Compounds for MIR571 Gene

No Compound Related Data Available

Transcripts for MIR571 Gene

mRNA/cDNA for MIR571 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR571 Gene

No ASD Table

Relevant External Links for MIR571 Gene

GeneLoc Exon Structure for
MIR571

Expression for MIR571 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR571 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR571

genes like me logo Genes that share expression patterns with MIR571: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR571 Gene

Orthologs for MIR571 Gene

Evolution for MIR571 Gene

ENSEMBL:
Gene Tree for MIR571 (if available)
TreeFam:
Gene Tree for MIR571 (if available)

No data available for Orthologs for MIR571 Gene

Paralogs for MIR571 Gene

No data available for Paralogs for MIR571 Gene

Variants for MIR571 Gene

Additional dbSNP identifiers (rs#s) for MIR571 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR571 Gene

Variant ID Type Subtype PubMed ID
dgv2697n106 CNV deletion 24896259
dgv5076n100 CNV gain 25217958
dgv971e214 CNV gain 21293372
esv2763816 CNV gain+loss 21179565
esv3893862 CNV gain 25118596
esv4769 OTHER complex 18987735
nsv1001899 CNV loss 25217958
nsv1006781 CNV gain 25217958
nsv1009336 CNV gain 25217958
nsv1074123 CNV deletion 25765185
nsv1150471 CNV deletion 26484159
nsv1161026 CNV duplication 26073780
nsv461144 CNV loss 19166990
nsv469736 CNV loss 16826518
nsv469996 CNV gain 18288195
nsv593198 CNV loss 21841781
nsv593199 CNV loss 21841781

Additional Variant Information for MIR571 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR571

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR571 Gene

Disorders for MIR571 Gene

Additional Disease Information for MIR571

No disorders were found for MIR571 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR571 Gene

Publications for MIR571 Gene

  1. Increased serum microRNAs are closely associated with the presence of microvascular complications in type 2 diabetes mellitus. (PMID: 26831044) Wang C … Wang J (Scientific reports 2016) 3 54
  2. Micro-RNA profiling in human serum reveals compartment-specific roles of miR-571 and miR-652 in liver cirrhosis. (PMID: 22412969) Roderburg C … Luedde T (PloS one 2012) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54
  4. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 54

Products for MIR571 Gene

Sources for MIR571 Gene