microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5705 Gene

Data sources for MIR5705 Gene:

Subcategory (RNA class) for MIR5705 Gene

miRNA

Aliases for MIR5705 Gene

External Ids for MIR5705 Gene

Previous GeneCards Identifiers for MIR5705 Gene

  • GC04U901519
  • GC04M088222

Summaries for MIR5705 Gene

Entrez Gene Summary for MIR5705 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5705 Gene

MIR5705 (MicroRNA 5705) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5705 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5705 Gene

Genomics for MIR5705 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5705 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J087304 Enhancer 0.7 ENCODE 0.7 -4.3 -4281 0.2 FEZF1 CEBPB FOXA2 CTBP1 ZNF843 TCF7L2 PRDM6 ZBTB40 ZNF217 SMARCE1 MIR5705 piR-43105-496 HSD17B13 KLHL8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5705 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5705 Gene

Latest Assembly
chr4:87,300,495-87,300,583
(GRCh38/hg38)
Size:
89 bases
Orientation:
Minus strand

Previous Assembly
chr4:88,221,647-88,221,735
(GRCh37/hg19 by Entrez Gene)
Size:
89 bases
Orientation:
Minus strand

chr4:88,221,647-88,221,735
(GRCh37/hg19 by Ensembl)
Size:
89 bases
Orientation:
Minus strand

Genomic View for MIR5705 Gene

Genes around MIR5705 on UCSC Golden Path with GeneCards custom track
MIR5705 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR5705 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5705 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5705 Gene

Proteins for MIR5705 Gene

Post-translational modifications for MIR5705 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5705 Gene

Domains & Families for MIR5705 Gene

Gene Families for MIR5705 Gene

HGNC:
genes like me logo Genes that share domains with MIR5705: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5705 Gene

Function for MIR5705 Gene

Phenotypes From GWAS Catalog for MIR5705 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5705 Gene

Localization for MIR5705 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5705 Gene

Pathways & Interactions for MIR5705 Gene

PathCards logo

SuperPathways for MIR5705 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5705 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5705 Gene

Drugs & Compounds for MIR5705 Gene

No Compound Related Data Available

Transcripts for MIR5705 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5705 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00007599D5_9606 precursor_RNA 89 3

RefSeq: NR_049891,

Ensembl: ENST00000579870 (view in UCSC) ,

miRBase: MI0019313,

URS000075EB7D_9606 miRNA 23 2

RefSeq: NR_049891,

miRBase: MIMAT0022499,

MIR5705 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5705 Gene

No ASD Table

Relevant External Links for MIR5705 Gene

GeneLoc Exon Structure for
MIR5705

No data available for mRNA/cDNA for MIR5705 Gene

Expression for MIR5705 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5705 Gene

Orthologs for MIR5705 Gene

Evolution for MIR5705 Gene

ENSEMBL:
Gene Tree for MIR5705 (if available)
TreeFam:
Gene Tree for MIR5705 (if available)

No data available for Orthologs for MIR5705 Gene

Paralogs for MIR5705 Gene

No data available for Paralogs for MIR5705 Gene

Variants for MIR5705 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR5705 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR5705 Gene

Variant ID Type Subtype PubMed ID
dgv1012e214 CNV loss 21293372
esv2667644 CNV deletion 23128226
esv2760913 CNV loss 21179565
esv3601271 CNV loss 21293372
nsv1004518 CNV gain 25217958
nsv1005615 CNV loss 25217958
nsv470050 CNV loss 18288195
nsv516203 CNV loss 19592680

Additional Variant Information for MIR5705 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5705

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5705 Gene

Disorders for MIR5705 Gene

Additional Disease Information for MIR5705

No disorders were found for MIR5705 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5705 Gene

Publications for MIR5705 Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR5705 Gene

Sources for MIR5705 Gene