microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5703 Gene

Subcategory (RNA class) for MIR5703 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR5703 Gene

  • MicroRNA 5703 2 3 5
  • Hsa-Mir-5703 3
  • MIMAT0022496 51
  • MI0019310 51
  • Mir-5703 3
  • MIR5703 2

External Ids for MIR5703 Gene

Previous GeneCards Identifiers for MIR5703 Gene

  • GC02U902469
  • GC02P228339

Summaries for MIR5703 Gene

Entrez Gene Summary for MIR5703 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5703 Gene

MIR5703 (MicroRNA 5703) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5703 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5703 Gene

Genomics for MIR5703 Gene

GeneHancer (GH) Regulatory Elements for MIR5703 Gene

Promoters and enhancers for MIR5703 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J227471 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 500.7 +1.5 1483 4.3 CTCF SIN3A NRF1 POLR2G SP1 PHF8 ZFX ZIC2 POLR2A ZBTB26 AGFG1 MIR5703 TM4SF20 HSALNG0022746 piR-47851-003
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5703 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5703 Gene

Genomic Locations for MIR5703 Gene
chr2:227,472,132-227,472,187
(GRCh38/hg38)
Size:
56 bases
Orientation:
Plus strand
chr2:228,336,848-228,336,903
(GRCh37/hg19)
Size:
56 bases
Orientation:
Plus strand

Genomic View for MIR5703 Gene

Genes around MIR5703 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5703 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5703 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5703 Gene

Proteins for MIR5703 Gene

Post-translational modifications for MIR5703 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5703 Gene

Domains & Families for MIR5703 Gene

Gene Families for MIR5703 Gene

HGNC:
genes like me logo Genes that share domains with MIR5703: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5703 Gene

Function for MIR5703 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5703 Gene

Localization for MIR5703 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5703 Gene

Pathways & Interactions for MIR5703 Gene

PathCards logo

SuperPathways for MIR5703 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR5703 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5703 Gene

Drugs & Compounds for MIR5703 Gene

No Compound Related Data Available

Transcripts for MIR5703 Gene

mRNA/cDNA for MIR5703 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
3 ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5703 Gene

No ASD Table

Relevant External Links for MIR5703 Gene

GeneLoc Exon Structure for
MIR5703

Expression for MIR5703 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5703 Gene

Orthologs for MIR5703 Gene

Evolution for MIR5703 Gene

ENSEMBL:
Gene Tree for MIR5703 (if available)
TreeFam:
Gene Tree for MIR5703 (if available)

No data available for Orthologs for MIR5703 Gene

Paralogs for MIR5703 Gene

No data available for Paralogs for MIR5703 Gene

Variants for MIR5703 Gene

Additional dbSNP identifiers (rs#s) for MIR5703 Gene

Additional Variant Information for MIR5703 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5703

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5703 Gene

Disorders for MIR5703 Gene

Additional Disease Information for MIR5703

No disorders were found for MIR5703 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5703 Gene

Publications for MIR5703 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR5703 Gene

Sources for MIR5703 Gene