microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5701-1 Gene

Subcategory (RNA class) for MIR5701-1 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR5701-1 Gene

  • MicroRNA 5701-1 2 3 5
  • Hsa-Mir-5701-1 3
  • MIMAT0022494 51
  • MIR5701-3 2
  • MIR5701-2 2
  • MI0031522 51
  • MI0019593 51
  • MIR5701-1 2
  • MI0019308 51

External Ids for MIR5701-1 Gene

Previous GeneCards Identifiers for MIR5701-1 Gene

  • GC15U901417
  • GC15P021155

Summaries for MIR5701-1 Gene

Entrez Gene Summary for MIR5701-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5701-1 Gene

MIR5701-1 (MicroRNA 5701-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5701-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5701-1 Gene

Genomics for MIR5701-1 Gene

GeneHancer (GH) Regulatory Elements for MIR5701-1 Gene

Promoters and enhancers for MIR5701-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J020940 Promoter 0.4 EPDnew 500.7 +0.2 167 0.1 NFATC3 MIR5701-1 piR-50623-001 LINC01193
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5701-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5701-1 Gene

Genomic Locations for MIR5701-1 Gene
chr15:20,940,252-20,940,333
(GRCh38/hg38)
Size:
82 bases
Orientation:
Plus strand
chr15:21,145,581-21,145,662
(GRCh37/hg19)
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR5701-1 Gene

Genes around MIR5701-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5701-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5701-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5701-1 Gene

Proteins for MIR5701-1 Gene

Post-translational modifications for MIR5701-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5701-1 Gene

Domains & Families for MIR5701-1 Gene

Gene Families for MIR5701-1 Gene

HGNC:
genes like me logo Genes that share domains with MIR5701-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5701-1 Gene

Function for MIR5701-1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5701-1 Gene

Localization for MIR5701-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5701-1 Gene

Pathways & Interactions for MIR5701-1 Gene

PathCards logo

SuperPathways for MIR5701-1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR5701-1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5701-1 Gene

Drugs & Compounds for MIR5701-1 Gene

No Compound Related Data Available

Transcripts for MIR5701-1 Gene

mRNA/cDNA for MIR5701-1 Gene

2 RNACentral transcripts :
3 REFSEQ mRNAs :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
4 miRBase transcripts :
7 ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5701-1 Gene

No ASD Table

Relevant External Links for MIR5701-1 Gene

GeneLoc Exon Structure for
MIR5701-1

Expression for MIR5701-1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5701-1 Gene

Orthologs for MIR5701-1 Gene

Evolution for MIR5701-1 Gene

ENSEMBL:
Gene Tree for MIR5701-1 (if available)
TreeFam:
Gene Tree for MIR5701-1 (if available)

No data available for Orthologs for MIR5701-1 Gene

Paralogs for MIR5701-1 Gene

No data available for Paralogs for MIR5701-1 Gene

Variants for MIR5701-1 Gene

Additional dbSNP identifiers (rs#s) for MIR5701-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR5701-1 Gene

Variant ID Type Subtype PubMed ID
dgv1360e59 CNV duplication 20981092
dgv1n1 OTHER inversion 15895083
dgv2174n100 CNV gain 25217958
dgv2175n100 CNV gain 25217958
dgv2179n100 CNV gain 25217958
dgv2181n100 CNV gain 25217958
dgv2182n100 CNV gain 25217958
dgv2183n100 CNV loss 25217958
dgv2188n100 CNV loss 25217958
dgv2189n100 CNV gain+loss 25217958
dgv2190n100 CNV gain+loss 25217958
dgv2191n100 CNV gain+loss 25217958
dgv2192n100 CNV loss 25217958
dgv2193n100 CNV gain+loss 25217958
dgv2211n100 CNV loss 25217958
dgv2212n100 CNV gain 25217958
dgv2213n100 CNV loss 25217958
dgv2214n100 CNV gain 25217958
dgv2222n100 CNV gain+loss 25217958
dgv2232n100 CNV loss 25217958
dgv2237n100 CNV gain 25217958
dgv2238n100 CNV gain 25217958
dgv2246n100 CNV gain+loss 25217958
dgv2250n100 CNV gain+loss 25217958
dgv2278n100 CNV gain 25217958
dgv2279n100 CNV loss 25217958
dgv2280n100 CNV loss 25217958
dgv2281n100 CNV gain+loss 25217958
dgv2282n100 CNV gain 25217958
dgv2283n100 CNV gain 25217958
dgv2284n100 CNV gain 25217958
dgv2287n100 CNV gain+loss 25217958
dgv2288n100 CNV gain 25217958
dgv2290n100 CNV gain+loss 25217958
dgv2293n100 CNV loss 25217958
dgv2297n100 CNV gain 25217958
dgv2298n100 CNV gain+loss 25217958
dgv2300n100 CNV loss 25217958
dgv2301n100 CNV loss 25217958
dgv2304n100 CNV gain 25217958
dgv2308n100 CNV loss 25217958
dgv2309n100 CNV gain 25217958
dgv2312n100 CNV gain 25217958
dgv2313n100 CNV loss 25217958
dgv2317n100 CNV gain 25217958
dgv2320n100 CNV loss 25217958
dgv2321n100 CNV gain+loss 25217958
dgv2324n100 CNV gain 25217958
dgv2325n100 CNV gain+loss 25217958
dgv2326n100 CNV gain 25217958
dgv2327n100 CNV gain 25217958
dgv2328n100 CNV gain 25217958
dgv2329n100 CNV loss 25217958
dgv2330n100 CNV loss 25217958
dgv2331n100 CNV gain+loss 25217958
dgv2332n100 CNV gain 25217958
dgv2333n100 CNV loss 25217958
dgv2334n100 CNV gain 25217958
dgv2335n100 CNV loss 25217958
dgv2336n100 CNV loss 25217958
dgv2337n100 CNV loss 25217958
dgv2339n100 CNV gain+loss 25217958
dgv2340n100 CNV gain+loss 25217958
dgv2341n100 CNV gain 25217958
dgv2343n100 CNV gain+loss 25217958
dgv2344n100 CNV loss 25217958
dgv2345n100 CNV gain 25217958
dgv2346n100 CNV loss 25217958
dgv2347n100 CNV loss 25217958
dgv2348n100 CNV gain+loss 25217958
dgv2350n100 CNV loss 25217958
dgv2351n100 CNV gain 25217958
dgv2352n100 CNV loss 25217958
dgv2353n100 CNV loss 25217958
dgv2354n100 CNV loss 25217958
dgv2355n100 CNV gain 25217958
dgv2356n100 CNV loss 25217958
dgv2357n100 CNV gain+loss 25217958
dgv2358n100 CNV loss 25217958
dgv2360n100 CNV gain+loss 25217958
dgv2361n100 CNV gain+loss 25217958
dgv2363n100 CNV loss 25217958
dgv2364n100 CNV gain 25217958
dgv2365n100 CNV gain+loss 25217958
dgv2367n100 CNV gain 25217958
dgv2368n100 CNV loss 25217958
dgv4162n54 CNV loss 21841781
dgv4164n54 CNV loss 21841781
dgv4166n54 CNV gain 21841781
dgv4180n54 CNV gain 21841781
dgv4182n54 CNV loss 21841781
dgv418n67 CNV gain 20364138
dgv4210n54 CNV gain 21841781
dgv4211n54 CNV gain 21841781
dgv4213n54 CNV loss 21841781
dgv4217n54 CNV loss 21841781
dgv4220n54 CNV gain+loss 21841781
dgv4221n54 CNV loss 21841781
dgv4222n54 CNV gain 21841781
dgv4223n54 CNV gain+loss 21841781
dgv4224n54 CNV loss 21841781
dgv4225n54 CNV loss 21841781
dgv4226n54 CNV loss 21841781
dgv4231n54 CNV gain 21841781
dgv4232n54 CNV gain 21841781
dgv4237n54 CNV loss 21841781
dgv4238n54 CNV gain 21841781
dgv4241n54 CNV loss 21841781
dgv4243n54 CNV loss 21841781
dgv4244n54 CNV loss 21841781
dgv4245n54 CNV loss 21841781
dgv4246n54 CNV loss 21841781
dgv4247n54 CNV loss 21841781
dgv4248n54 CNV loss 21841781
dgv4249n54 CNV loss 21841781
dgv43n16 CNV insertion 17901297
dgv91e55 CNV gain 17911159
dgv92e55 CNV gain 17911159
dgv93e55 CNV gain 17911159
dgv95e55 CNV loss 17911159
dgv96e55 CNV loss 17911159
esv1004259 OTHER inversion 20482838
esv21579 CNV gain+loss 19812545
esv2427986 CNV gain 19546169
esv2673548 CNV deletion 23128226
esv2751488 CNV loss 17911159
esv2751492 CNV gain 17911159
esv29956 CNV loss 18421352
esv33051 CNV gain+loss 17666407
esv3400852 CNV duplication 20981092
esv3584679 CNV loss 24956385
esv3584832 CNV gain 24956385
esv3584854 CNV gain 24956385
esv3584865 CNV gain 24956385
esv3892595 CNV gain+loss 25118596
esv3892607 CNV gain 25118596
esv3892609 CNV gain 25118596
esv3892612 CNV gain 25118596
esv3892620 CNV gain+loss 25118596
esv3892621 CNV gain+loss 25118596
esv988919 CNV loss 20482838
nsv1045315 CNV loss 25217958
nsv1045895 CNV gain+loss 25217958
nsv1055063 CNV gain+loss 25217958
nsv1112662 CNV deletion 24896259
nsv1128716 CNV duplication 24896259
nsv1147516 CNV duplication 26484159
nsv1150328 CNV duplication 26484159
nsv1160218 CNV duplication 26073780
nsv1160227 CNV duplication 26073780
nsv1160228 CNV deletion 26073780
nsv428296 CNV gain+loss 18775914
nsv433282 CNV loss 18776910
nsv433283 CNV loss 18776910
nsv436198 CNV deletion 17901297
nsv469803 CNV gain 16826518
nsv471675 CNV gain+loss 15918152
nsv511040 OTHER inversion 20534489
nsv567312 CNV gain 21841781
nsv567597 CNV loss 21841781
nsv567604 CNV loss 21841781
nsv567636 CNV loss 21841781
nsv567641 CNV gain 21841781
nsv7260 OTHER inversion 18451855
nsv817667 CNV gain 17921354
nsv819612 CNV gain 19587683
nsv819770 CNV gain 19587683
nsv821678 CNV loss 15273396
nsv832916 CNV gain+loss 17160897
nsv9179 CNV gain+loss 18304495
nsv952320 CNV duplication 24416366
nsv952555 CNV duplication 24416366

Additional Variant Information for MIR5701-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5701-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5701-1 Gene

Disorders for MIR5701-1 Gene

Additional Disease Information for MIR5701-1

No disorders were found for MIR5701-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5701-1 Gene

Publications for MIR5701-1 Gene

  1. Systemic Analysis of miRNAs in PD Stress Condition: miR-5701 Modulates Mitochondrial-Lysosomal Cross Talk to Regulate Neuronal Death. (PMID: 28710704) Prajapati P … Singh R (Molecular neurobiology 2018) 3 54
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR5701-1 Gene

Sources for MIR5701-1 Gene