microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5692A2 Gene

Data sources for MIR5692A2 Gene:

RNA type for MIR5692A2 Gene

miRNA

Aliases for MIR5692A2 Gene

External Ids for MIR5692A2 Gene

Previous GeneCards Identifiers for MIR5692A2 Gene

  • GC08U901605
  • GC08P012580

Summaries for MIR5692A2 Gene

Entrez Gene Summary for MIR5692A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5692A2 Gene

MIR5692A2 (MicroRNA 5692a-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5692A2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5692A2 Gene

Genomics for MIR5692A2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5692A2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J012721 Enhancer 0.3 Ensembl ENCODE 0.7 +2.2 2209 0.3 LONRF1 MIR5692A2 lnc-FAM86B2-6 FAM86B2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5692A2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5692A2 Gene

Latest Assembly
chr8:12,719,132-12,719,190
(GRCh38/hg38)
Size:
59 bases
Orientation:
Plus strand

Previous Assembly
chr8:12,576,641-12,576,699
(GRCh37/hg19 by Entrez Gene)
Size:
59 bases
Orientation:
Plus strand

chr8:12,576,636-12,576,704
(GRCh37/hg19 by Ensembl)
Size:
69 bases
Orientation:
Plus strand

Alternative Locations (GRCh38/hg38)

  • chr8(PATCHES):5,914,486-5,914,544 (+)

Genomic View for MIR5692A2 Gene

Genes around MIR5692A2 on UCSC Golden Path with GeneCards custom track
MIR5692A2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR5692A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5692A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5692A2 Gene

Proteins for MIR5692A2 Gene

Post-translational modifications for MIR5692A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5692A2 Gene

Domains & Families for MIR5692A2 Gene

Gene Families for MIR5692A2 Gene

HGNC:
genes like me logo Genes that share domains with MIR5692A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5692A2 Gene

Function for MIR5692A2 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5692A2 Gene

Localization for MIR5692A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5692A2 Gene

Pathways & Interactions for MIR5692A2 Gene

PathCards logo

SuperPathways for MIR5692A2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5692A2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5692A2 Gene

Drugs & Compounds for MIR5692A2 Gene

No Compound Related Data Available

Transcripts for MIR5692A2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5692A2 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000759C98_9606 precursor_RNA 59 3

RefSeq: NR_049876,

Ensembl: ENST00000582551 (view in UCSC) ,

miRBase: MI0019298,

URS000075A42B_9606 miRNA 22 2

RefSeq: NR_049875, NR_049876,

miRBase: MIMAT0022484,

MIR5692A2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5692A2 Gene

No ASD Table

Relevant External Links for MIR5692A2 Gene

GeneLoc Exon Structure for
MIR5692A2

No data available for mRNA/cDNA for MIR5692A2 Gene

Expression for MIR5692A2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5692A2 Gene

Orthologs for MIR5692A2 Gene

Evolution for MIR5692A2 Gene

ENSEMBL:
Gene Tree for MIR5692A2 (if available)
TreeFam:
Gene Tree for MIR5692A2 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR5692A2

No data available for Orthologs for MIR5692A2 Gene

Paralogs for MIR5692A2 Gene

No data available for Paralogs for MIR5692A2 Gene

Variants for MIR5692A2 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR5692A2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR5692A2 Gene

Variant ID Type Subtype PubMed ID
dgv154e203 CNV gain+loss 21179565
dgv244e55 CNV gain 17911159
dgv246e55 CNV gain 17911159
dgv7016n100 CNV gain 25217958
dgv7040n100 CNV gain 25217958
dgv7077n100 CNV gain 25217958
dgv7082n100 CNV gain 25217958
esv2759546 CNV loss 17122850
esv2759593 CNV gain+loss 17122850
nsv1025471 CNV gain 25217958
nsv1029648 CNV gain 25217958
nsv1078596 CNV duplication 25765185
nsv1132670 CNV duplication 24896259
nsv428178 CNV gain 18775914
nsv970555 CNV duplication 23825009

Additional Variant Information for MIR5692A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5692A2
Leiden Open Variation Database (LOVD)
MIR5692A2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5692A2 Gene

Disorders for MIR5692A2 Gene

Additional Disease Information for MIR5692A2

No disorders were found for MIR5692A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5692A2 Gene

Publications for MIR5692A2 Gene

  1. MiR-5692a promotes proliferation and inhibits apoptosis by targeting HOXD8 in hepatocellular carcinoma. (PMID: 30941968) Sun S … Cui H (Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2019) 3
  2. MiR-5692a promotes the invasion and metastasis of hepatocellular carcinoma via MMP9. (PMID: 30070322) Sun SJ … Cui HW (European review for medical and pharmacological sciences 2018) 3
  3. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

No data available for Mastermind for MIR5692A2 Gene

Products for MIR5692A2 Gene

Sources for MIR5692A2 Gene