microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5691 Gene

Subcategory (RNA class) for MIR5691 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR5691 Gene

  • MicroRNA 5691 2 3 5
  • Hsa-Mir-5691 2 3
  • MIR5691 2 5
  • MIMAT0022483 50
  • MI0019296 50

External Ids for MIR5691 Gene

Previous GeneCards Identifiers for MIR5691 Gene

  • GC11U901905
  • GC11M009113

Summaries for MIR5691 Gene

Entrez Gene Summary for MIR5691 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5691 Gene

MIR5691 (MicroRNA 5691) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5691 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5691 Gene

Genomics for MIR5691 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5691 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J009091 Promoter 0.9 EPDnew Ensembl 600.7 -1.1 -1122 1.8 EZH2 ZFX KLF9 MIR5691 SCUBE2 KRT8P41 TMEM41B lnc-SCUBE2-1 NRIP3
GH11J009088 Enhancer 0.4 ENCODE 600.7 +1.0 953 1 KLF9 KLF1 NCOA3 ENSG00000286935 MIR5691 TMEM9B TMEM9B-AS1 SCUBE2 lnc-SCUBE2-1 NRIP3
GH11J009093 Enhancer 0.6 Ensembl ENCODE 0.7 -3.2 -3222 0.8 CTCF RAD21 SMC3 KRT8P41 MIR5691 lnc-SCUBE2-1 SCUBE2 NRIP3
GH11J009092 Promoter 0.4 Ensembl 0.7 -2.4 -2421 0.4 EZH2 KRT8P41 MIR5691 SCUBE2 lnc-SCUBE2-1 NRIP3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5691 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5691 Gene

Genomic Locations for MIR5691 Gene
chr11:9,090,312-9,090,379
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand
chr11:9,111,859-9,111,926
(GRCh37/hg19)
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR5691 Gene

Genes around MIR5691 on UCSC Golden Path with GeneCards custom track
MIR5691 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR5691 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5691 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5691 Gene

Proteins for MIR5691 Gene

Post-translational modifications for MIR5691 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5691 Gene

Domains & Families for MIR5691 Gene

Gene Families for MIR5691 Gene

HGNC:
genes like me logo Genes that share domains with MIR5691: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5691 Gene

Function for MIR5691 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5691 Gene

Localization for MIR5691 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5691 Gene

Pathways & Interactions for MIR5691 Gene

PathCards logo

SuperPathways for MIR5691 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5691 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5691 Gene

Drugs & Compounds for MIR5691 Gene

No Compound Related Data Available

Transcripts for MIR5691 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5691 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A52B_9606 precursor_RNA 68 4

HGNC: 43545,

RefSeq: NR_049874,

Ensembl: ENST00000579525 (view in UCSC) ,

miRBase: MI0019296,

URS000075A37B_9606 miRNA 22 2

RefSeq: NR_049874,

miRBase: MIMAT0022483,

MIR5691 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5691 Gene

No ASD Table

Relevant External Links for MIR5691 Gene

GeneLoc Exon Structure for
MIR5691

No data available for mRNA/cDNA for MIR5691 Gene

Expression for MIR5691 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5691 Gene

Orthologs for MIR5691 Gene

Evolution for MIR5691 Gene

ENSEMBL:
Gene Tree for MIR5691 (if available)
TreeFam:
Gene Tree for MIR5691 (if available)

No data available for Orthologs for MIR5691 Gene

Paralogs for MIR5691 Gene

No data available for Paralogs for MIR5691 Gene

Variants for MIR5691 Gene

Additional dbSNP identifiers (rs#s) for MIR5691 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR5691 Gene

Variant ID Type Subtype PubMed ID
esv33264 CNV loss 17666407
nsv467706 CNV loss 19166990
nsv499766 OTHER inversion 21111241
nsv553454 CNV loss 21841781
nsv553455 CNV loss 21841781
nsv7215 OTHER inversion 18451855
nsv951307 CNV deletion 24416366

Additional Variant Information for MIR5691 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5691

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5691 Gene

Disorders for MIR5691 Gene

Additional Disease Information for MIR5691

No disorders were found for MIR5691 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5691 Gene

Publications for MIR5691 Gene

  1. Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain. (PMID: 23279374) Athanasiadis G … Soria JM (Journal of thrombosis and haemostasis : JTH 2013) 3
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR5691 Gene

Sources for MIR5691 Gene